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The Role of Seven-Transmembrane Domain MLO Proteins, Heterotrimeric G-Proteins, and Monomeric RAC/ROPs in Plant Defense

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Book cover Integrated G Proteins Signaling in Plants

Part of the book series: Signaling and Communication in Plants ((SIGCOMM))

Abstract

MLO proteins are structurally reminiscent of G-protein-coupled receptors but act independently of heterotrimeric G-proteins as major susceptibility factors to powdery mildew fungi. In barley, monomeric RAC/ROPs, instead of heterotrimeric G-proteins, MLO-dependently modulate susceptibility to powdery mildew, which may involve functions in cytoskeleton remodeling. In contrast to the role of RAC/ROPs in barley susceptibility to powdery mildew, rice OsRAC1 exerts a central function in basal and effector-triggered immunity. In this context, a functional cooperation with the heterotrimeric G-protein subunit, Gα, and additional protein complexes with functions in plant immunity has been discovered. These polypeptides together modulate the oxidative burst and regulate the abundance of defense-associated messenger RNAs and defense proteins. This chapter highlights the interconnection of MLO, RAC/ROP, and heterotrimeric G-proteins in plant immunity.

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Authors and Affiliations

  1. Department of Plant-Microbe Interactions, Max-Planck Institute for Plant Breeding Research, Carl-von-Linné-Weg 10, Köln, 50829, Germany

    Justine Lorek & Ralph Panstruga

  2. Technische Universität München, Lehrstuhl für Phytopathologie, Am Hochanger 2, Freising-Weihenstephan, München, 85350, Germany

    Ralph Hückelhoven

Authors
  1. Justine Lorek
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  2. Ralph Panstruga
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  3. Ralph Hückelhoven
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Corresponding author

Correspondence to Ralph Panstruga .

Editor information

Editors and Affiliations

  1. Dept. Plant Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv, 69978, Israel

    Shaul Yalovsky

  2. Inst. Zelluläre und Molekulare, Universität Bonn, Kirschallee 1, Bonn, 53115, Germany

    František Baluška

  3. Dept. Biology & Pharmacology, University of North Carolina, Coker Hall 317, Chapel Hill, 27599, U.S.A.

    Alan Jones

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Lorek, J., Panstruga, R., Hückelhoven, R. (2010). The Role of Seven-Transmembrane Domain MLO Proteins, Heterotrimeric G-Proteins, and Monomeric RAC/ROPs in Plant Defense. In: Yalovsky, S., Baluška, F., Jones, A. (eds) Integrated G Proteins Signaling in Plants. Signaling and Communication in Plants. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03524-1_11

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