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Bayesian Multi-topic Microarray Analysis with Hyperparameter Reestimation

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Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 5678))

Abstract

This paper provides a new method for multi-topic Bayesian analysis for microarray data. Our method achieves a further maximization of lower bounds in a marginalized variational Bayesian inference (MVB) for Latent Process Decomposition (LPD), which is an effective probabilistic model for microarray data. In our method, hyperparameters in LPD are updated by empirical Bayes point estimation. The experiments based on microarray data of realistically large size show efficiency of our hyperparameter reestimation technique.

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© 2009 Springer-Verlag Berlin Heidelberg

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Masada, T., Hamada, T., Shibata, Y., Oguri, K. (2009). Bayesian Multi-topic Microarray Analysis with Hyperparameter Reestimation. In: Huang, R., Yang, Q., Pei, J., Gama, J., Meng, X., Li, X. (eds) Advanced Data Mining and Applications. ADMA 2009. Lecture Notes in Computer Science(), vol 5678. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03348-3_26

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  • DOI: https://doi.org/10.1007/978-3-642-03348-3_26

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-03347-6

  • Online ISBN: 978-3-642-03348-3

  • eBook Packages: Computer ScienceComputer Science (R0)

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