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Posttreatment-Related Marrow Changes

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Pediatric and Adult MRI Atlas of Bone Marrow

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Abstract

Current medical treatments, including radiation therapy, chemotherapy, and hematopoietic growth factors, may affect the MR imaging appearance of bone marrow. A robust understanding of posttreatment marrow changes is required in order to differentiate these expected findings from pathologic marrow processes. Therapy-induced MR imaging characteristics are related to alterations in bone marrow cellular composition, vascularity, and metabolism. Therefore, posttreatment changes evolve in a time-dependent fashion and on occasion may be reversible. Therapy-specific complications such as radiation osteonecrosis and insufficiency fractures must also be differentiated and recognized by MR imaging.

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Authors and Affiliations

  1. Department of Radiology, Ronald Reagan UCLA Medical Center, University of California Los Angeles, Los Angeles, CA, USA

    Kathleen Ruchalski MD (Assistant Professor of Radiology), Kambiz Motamedi MD (Professor of Radiology) & Leanne L. Seeger MD (Professor of Radiology)

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  1. Kathleen Ruchalski MD
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  2. Kambiz Motamedi MD
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  3. Leanne L. Seeger MD
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© 2016 Springer-Verlag Berlin Heidelberg

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Ruchalski, K., Motamedi, K., Seeger, L.L. (2016). Posttreatment-Related Marrow Changes. In: Pediatric and Adult MRI Atlas of Bone Marrow. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02740-6_2

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  • DOI: https://doi.org/10.1007/978-3-642-02740-6_2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-02739-0

  • Online ISBN: 978-3-642-02740-6

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