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Fiber-Optic Raman Probes for Biomedical and Pharmaceutical Applications

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Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

Abstract

This chapter reviews the development of optical fiber probe Raman systems and their applications in life science and pharmaceutical studies. Especially, it is focused on miniaturized Raman probes which open new era in the spectroscopy of the life forms. The chapter also introduces the important optical properties of conventional optical fibers to use for Raman probes, as well as new types of optical fiber and devices, such as hollow optical fibers and photonic crystal fibers.

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Acknowledgments

We would like to express our sincere gratitude to Prof. Yukihiro Ozaki (Kwansei Gakuin Univ.), Prof. Yuji Matsuura (Tohoku Univ.), Prof. Toru Shimosegawa (Tohoku Univ.), Prof. Masakazu Toi (Kyoto Univ.), and Dr. Hideo Tashiro (RIKEN) for the fruitful discussions and technical support. We also feel grateful to Mr. Gen’ichi Kanai (Machida Endoscope Co. Ltd.), Mr. Nobuo Ura (Soma Opt. Co. Ltd.), and Dr. Koji Masutani (Micro Science Co. Ltd.) for their cooperation in the development and technical support.

Author information

Authors and Affiliations

  1. Care of Springer, Care of Springer, Care of Springer

    Hidetoshi Sato

  2. Care of Springer, Care of Springer, Care of Springer

    Hideyuki Shinzawa

  3. Care of Springer, Care of Springer, Care of Springer

    Yuichi Komachi

Authors
  1. Hidetoshi Sato
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  2. Hideyuki Shinzawa
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  3. Yuichi Komachi
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Editor information

Editors and Affiliations

  1. Science & Technology Facilities Council, Central Laser Facility, Didcot, Oxon., OX11 0QX, United Kingdom

    Pavel Matousek

  2. Dept. Chemistry, University of Michigan, Ann Arbor, 48109-1055, U.S.A.

    Michael D. Morris

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Sato, H., Shinzawa, H., Komachi, Y. (2010). Fiber-Optic Raman Probes for Biomedical and Pharmaceutical Applications. In: Matousek, P., Morris, M. (eds) Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02649-2_2

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  • DOI: https://doi.org/10.1007/978-3-642-02649-2_2

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  • Print ISBN: 978-3-642-02648-5

  • Online ISBN: 978-3-642-02649-2

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