Abstract
Blood and urine are frequently analyzed for their chemical content. Raman spectroscopy, with its high specificity, can provide chemical information in a non-contact and potentially non-invasive manner. In this chapter, key experimental and analytical techniques for converting Raman spectra into quantitative chemical concentration measurements are presented, along with a survey of the current status of the field.
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A.J. Berger, T.-W. Koo, I. Itzkan, G.L. Horowitz, M.S. Feld, Appl. Opt. 38(13), 2916 (1999)
A.M.K. Enejder, T.-W. Koo, J. Oh, M. Hunter, S. Sasic, M.S. Feld, Opt. Lett. 27(22), 2004 (2002)
J.T. Motz, M. Hunter, L.H. Galindo, J.A. Gardecki, J.R. Kramer, R.R. Dasari, M.S. Feld, Appl. Opt. 43(3), 542 (2004)
J.Y. Qu, L. Shao, Rev. Sci. Inst. 72(6), 2717 (2001)
D. Qi, A.J. Berger, Appl. Opt. 46(10), 1726 (2007)
J. Chaiken, W. Finney, P.E. Knudson, R.S. Weinstock, M. Khan, R.J. Bussjager, D. Hagrman, P. Hagrman, Y. Zhao, C.M. Peterson, K. Peterson, J. Biomed. Opt. 10(3), 031111 (2005)
C.A. Lieber, A. Mahadevan-Jansen, Appl. Spectrosc. 57(11), 1363–1367 (2003)
N.K. Afseth, V.H. Segtnan, J.P. Wold, Appl. Spectrosc. 60(2), 1358 (2006)
G. Schulze, A. Jirasek, M.M.L. Yu, A. Lim, R.F.B. Turner, M.W. Blades, Appl. Spectrosc. 59(5), 545 (2005)
D.M. Haaland, E.V. Thomas, Anal. Chem. 60, 1193 (1988)
A.J. Berger, T.-W. Koo, I. Itzkan, M.S. Feld, Anal. Chem. 70, 623 (1998)
W.-C. Shih, K.L. Bechtel, M.S. Feld, Anal. Chem. 79, 234 (2007)
W.-C. Shih, K.L. Bechtel, M.S. Feld, Opt. Express 16(17), 12726 (2008)
K.L. Bechtel, W.-C. Shih, M.S. Feld, Opt. Express 16(17), 12737 (2008)
M.J. Goetz Jr., G.L. Coté, R. Erckens, W. March, M. Motamedi, IEEE Trans. Biomed. Eng. 42(7), 728 (1995)
A.J. Berger, Y. Wang, M.S. Feld, Appl. Opt. 35(1), 209 (1996)
O.R. Sćepanović, K.L. Bechtel, A.S. Haka, W.-C. Shih, T.-W. Koo, A.J. Berger, M.S. Feld, J. Biomed. Opt. 12(6), 064012 (2007)
J.Y. Qu, B.C. Wilson, D. Suria, Appl. Opt. 38(25), 5491 (1999)
D. Rohleder, W. Kiefer, W. Petrich, Analyst 129, 906 (2004)
D. Rohleder, G. Kocherscheidt, K. Gerber, W. Kiefer, W. Kohler, J. Mocks, W. Petrich, J. Biomed. Opt. 10(3), 031108 (2005)
P.J. Caspers, G.W. Lucassen, G.J. Puppels, Biophys. J. 85, 572 (2003)
A.M.K. Enejder, T.G. Scecina, J. Oh, M. Hunter, W.-Ch. Shih, S. Sasic, G.L. Horowitz, M.S. Feld, J. Biomed. Opt. 10(3), 031114 (2005)
W.R. Premasiri, R.H. Clarke, M.E. Womble, Lasers Surg. Med. 28, 330 (2001)
X. Dou, Y. Yamaguchi, H. Yamamoto, S. Doi, Y. Ozaki, Biospectroscopy 3(2), 113 (1998)
J.W. McMurdy III, A.J. Berger, Appl. Spectrosc. 57(3), 522 (2003)
C.S. Park. J.M. Choi, K.S. Park, in Proc. IEEE Eng. Med. Biol. 27th Annual Conference, Shanghai, China, Septr 2005, p. 1991
C. Park, K. Kim, J. Choi, K. Park, Physiol. Meas. 28, 583 (2007)
A.E. Guimaraes, M.T.T. Pacheco, L. Silveira Jr., D. Barsottini, J. Duarte, A.B. Villaverde, R.A. Zangaro, Spectroscopy 20, 185 (2006)
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Berger, A.J. (2010). Raman Spectroscopy of Blood and Urine Specimens. In: Matousek, P., Morris, M. (eds) Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02649-2_16
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DOI: https://doi.org/10.1007/978-3-642-02649-2_16
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