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Pharmaceuticals

  • Andreas SchiermeyerEmail author
  • Stefan Schillberg
Chapter
Part of the Biotechnology in Agriculture and Forestry book series (AGRICULTURE, volume 64)

Abstract

Plants and plant cell cultures have been evaluated over the past two decades as alternative production platforms for biopharmaceuticals. A large number of candidate proteins has been successfully produced in a range of plant species and the most advanced products are currently progressing through the clinical development stages. We first discuss principles for the production of plant-made pharmaceuticals including plant transformation procedures, post-translational modifications, and downstream processing. We then highlight some of the most advanced plant-made biopharmaceuticals currently in clinical development for human medical use.

Keywords

Tobacco Mosaic Virus Plastid Genome Production Platform Transplastomic Plant Terminal Sialic Acid Residue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.Department of Plant BiotechnologyFraunhofer Institute for Molecular Biology and Applied Ecology (IME)AachenGermany

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