Abstract
This paper introduces a photon subsurface scattering method to simulate light transport in human colon tissue. First the theoretical model and parameters of human tissue including autofluorescence phenomenon was presented. Then it was described the Monte-Carlo model of steady-state light transport in multi-layered colon. The goal of this investigation is to simulate the light propagation in tissue and to collect the data containing the effect of fluorescence. This information will be used to generate images. Pictures taken for different adjustment of light parameters should define a configuration for which cancerous structures are visible quickly and precisely. Real medical devices can adjust their parameters to the simulated ones and help with efficient diagnosis and recognition of diseased structures.
Keywords
Supported by Ministry of Science and Higher Education grant R13 046 02.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Latos, W., Kawczyk-Krupka, A., Ledwon, A., Kosciarz-Grzesiok, A., Misiak, A., Sieron-Stoltny, K., Sieron, A.: The role of autofluorescence colonoscopy in diagnosis and management of Solitary Rectal Ulcer Syndrome. In: SPIE Photonics West Conferences and Courses. Biomedical Optics. Imaging, Manipulation and analysis of Biomolecules, Cells and Tissues VI. Cell and tissue functional imaging, San Jose (2008)
Zhu, C., Liu, Q., Ramanujam, N.: Effect of fiber optic probe geometry on depth-resolved fluorescence measurements from epithelial tissues: a Monte Carlo simulation. Journal of Biomedical Optics 8(2), 237–247 (2003)
Ledwon, A., Bieda, R., Kawczyk-Krupka, A., Polanski, A., Wojciechowski, K., Sieron- Stoltny, K., Sieron, A.: The possibilities of improvement the sensitivity of cancer fluorescence diagnostics by computer image processing. In: SPIE Photonics West- Conferences and Courses. Biomedical Optics. Biomedical Optics. Imaging, Manipulation and analysis of Biomolecules, Cells and Tissues VI. Advances in Bioimaging: Computation and Image Analysis, San Jose (2008)
Dacosta, R.S., Andersson, H., Wilson, B.C.: Molecular Fluorescence Excitation – Emission Matrices Relevant to Tissue Spectroscopy. Photochem. Photobiol. 78(4), 384–392 (2003)
Wang, L., Jacques, S.L.: Monte Carlo Modeling of Light Transport in Multi-layered Tissues in Standard C. University of Texas M. D. Anderson Cancer Center (1992)
Jensen, H.W., Marschner, S.R., Levoy, M., Hanrahan, P.: A Practical Model for Subsurface Light Transport. In: Proceedings to Siggraph, pp. 511–518 (2001)
Donner, C., Jensen, H.W.: Rendering Translucent Materials Using Photon Diffusion. In: Eurographics Symposium on Rendering, pp. 234–251 (2007)
Quan, L., Nimunkar, A., Hagl, D.M.: Verification of Monte Carlo modeling of fluorescence in turbid medium. Optical Society of America (2001)
Eker, C.: Optical Characterization of tissue for medical diagnostics. Doctoral Thesis. Department of Physics. Lund Institute of Technology (October 1999)
Marin, N.M.: Autofluorescence and diffuse reflectance patterns in cervical spectroscopy. Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy. The University of Texas at Austin (December 2005)
Mertens, T., Kautz, J., Bekaert, P., Van Reeth, F., Seidel, H.P.: Efficient Rendering of Local Subsurface Scattering. Computer Graphics Forum 24(1), 41–49 (2005)
Zonios, G.I., Cothren, R.M., Arendt, J.T., Wu, J., Van Dam, J., Crawford, J.M., Manoharan, R., Feld, M.S.: Morphological Model of Human Colon Tissue Fluorescence. IEEE Transactions on Biomedical Engineering 43(2) (1996)
Ramanujam, N.: Fluorescence Spectroscopy In Vivo. In: Meyers, R.A. (ed.) Encyclopedia of Analytical Chemistry, pp. 20–56. John Wiley & Sons Ltd., Chichester (2000)
Pharr, M., Humphereys, G.: Physically based rendering. From theory to implementation. Morgan Kaufmann, San Francisco (2004)
Swenson, E.A., Rosenberger, A.E., Howell, P.J.: Validation of Endoscopy for Determination of Maturity in Small Salmonids and Sex of Mature Individuals. Transactions of the American Fisheries Society 136, 994–998 (2007)
Called de Calipso, N.: Optical Short Course International. In the box Optics of Digital Projectors Bi-monthly eNewsletter. 6679, Tuscon, AZ, USA, www.oscintl.com
Day, D.C.: Technical Report. Spectral Sensitivities of the Sinarback 54 Camera, http://www.art-si.org
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2009 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Zacher, A. (2009). Numerical Simulation of Endoscopic Images in Photodynamic Diagnosis. In: Bolc, L., Kulikowski, J.L., Wojciechowski, K. (eds) Computer Vision and Graphics. ICCVG 2008. Lecture Notes in Computer Science, vol 5337. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02345-3_33
Download citation
DOI: https://doi.org/10.1007/978-3-642-02345-3_33
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-02344-6
Online ISBN: 978-3-642-02345-3
eBook Packages: Computer ScienceComputer Science (R0)