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Modulation of T Cell-Mediated Immune Responses by Natural Killer Cells

  • Alessandra ZingoniEmail author
  • Cristina Cerboni
  • Michele Ardolino
  • Angela Santoni
Chapter

Abstract

Natural Killer (NK) cells are lymphoid cells that participate in innate immunity and in early defense against infections and tumors. NK cells express cell surface activating and inhibitory receptors that allow them to recognize and kill infected or tumor cells and rapidly produce cytokines and chemokines. Increasing evidence asserts an important immunomodulatory role of NK cells. We will discuss different mechanisms used by NK cells to regulate T cell-mediated immune responses.

Keywords

Dendritic Cell Natural Killer Cell Experimental Autoimmune Encephalomyelitis Treg Cell Activate Natural Killer Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Alessandra Zingoni
    • 1
    Email author
  • Cristina Cerboni
    • 1
  • Michele Ardolino
    • 1
  • Angela Santoni
    • 1
  1. 1.Department of Experimental MedicineUniversity “Sapienza”RomeItaly

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