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Imaging of HIV/Host Protein Interactions

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HIV Interactions with Host Cell Proteins

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 339))

Abstract

HIV-1 relies on a myriad of interactions with host cell proteins to carry out its life cycle. Traditional biochemical approaches to probe protein–protein interactions are limited in their ability to study the spatial and dynamic interactions that take place in the context of an intact cell. However, issues such as localization and dynamics of interactions between viral and host proteins can be well addressed utilizing fluorescent imaging methods. The past decade has brought about the development of many novel fluorescent imaging techniques which have proved useful to describe the interaction of HIV-1 proteins with the host cell.

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Author information

Authors and Affiliations

  1. Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Ward 8-140, 303 E. Chicago Avenue, Chicago, IL, 60611, USA

    Thomas J. Hope

Authors
  1. Cindy M. Danielson
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  2. Thomas J. Hope
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Corresponding author

Correspondence to Thomas J. Hope .

Editor information

Editors and Affiliations

  1. School of Medicine, Dept. Pediatrics, Emory University, Uppergate Drive NE., 2015, Atlanta, 30322, Georgia, USA

    Paul Spearman

  2. HIV Drug Resistance Program, National Cancer Institute-Frederick, Frederick, Maryland, USA

    Eric O. Freed

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© 2009 Springer-Verlag Berlin Heidelberg

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Danielson, C.M., Hope, T.J. (2009). Imaging of HIV/Host Protein Interactions. In: Spearman, P., Freed, E. (eds) HIV Interactions with Host Cell Proteins. Current Topics in Microbiology and Immunology, vol 339. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02175-6_6

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