Zusammenfassung
Die Sekretion der Thrombozytengranula (α-Granula, dichte Granula und Lysosomen) stellt einen zentralen Aktivierungsschritt der Thrombozyten dar, der essenziell für die Bildung eines stabilen Thrombozytenaggregats/Thrombus ist. Blutungsneigungen, die durch Störungen in der Granulabiogenese oder Degranulierung hervorgerufen werden, wie z. B. das “gray platelet syndrome„, oder das “storage pool disease„, verdeutlichen die Wichtigkeit der Thrombozytensekretion für eine intakte Hämostase.
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Jurk, K., Kehrel, B.E. (2010). Thrombozytensekretion. In: Pötzsch, B., Madlener, K. (eds) Hämostaseologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01544-1_8
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