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Uroonkologie pp 3–15Cite as

Molekularbiologie und Genetik

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Zusammenfassung

Durch die Entwicklung von »targeted drugs«, deren Wirksamkeit auf der Inhibition bedeutsamer biologischer Prozesse der Tumorzelle beruht, hat die Kenntnis molekularer Veränderungen solider Tumoren einen neuen Stellenwert im klinischen Alltag erhalten. Es ist erkennbar geworden, dass sich die »Molekulare Diagnostik« nicht nur zum Nachweis von Tumoren eignet, sondern uns darüber hinaus in die Lage versetzen wird, über den Genotyp das klinische Verhalten eines Tumors vorherzusagen. Dies kann z. B. für die Einschätzung der Prognose nach operativer Therapie, die Wahl einer Therapie (z. B. adjuvant) oder die Auswahl von »targeted drugs« genutzt werden.

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Authors and Affiliations

  1. Urologische Klinik und Poliklinik, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Fetscherstraße 74, 01307, Dresden

    Priv. Doz. Dr. med. Marc-Oliver Grimm & Dipl.-Chem. Daniela Wuttig

  2. Klinik für Urologie u. Kinderurologie, Universitätsklinikum Erlangen, Krankenhausstr. 12, 91054, Erlangen

    Prof. Dr. med. Bernd Wullich

  3. Universitätsklinikum Düsseldorf, Moorenstraße 5, 40225, Düsseldorf

    Prof. Dr. rer. nat. Wolfgang Arthur Schulz (Laborleiter der Urologischen Klinik)

Authors
  1. Priv. Doz. Dr. med. Marc-Oliver Grimm
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  2. Dipl.-Chem. Daniela Wuttig
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  3. Prof. Dr. med. Bernd Wullich
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  4. Prof. Dr. rer. nat. Wolfgang Arthur Schulz
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Editors and Affiliations

  1. Universitätsklinikum Essen, Hufelandstraße 55, 45122, Essen

    Herbert Rübben (Direktor der Klinik und Poliklinik für Urologie) (Direktor der Klinik und Poliklinik für Urologie)

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© 2009 Springer Medizin Verlag Heidelberg

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Grimm, MO., Wuttig, D., Wullich, B., Schulz, W.A. (2009). Molekularbiologie und Genetik. In: Rübben, H. (eds) Uroonkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01382-9_1

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  • DOI: https://doi.org/10.1007/978-3-642-01382-9_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-01381-2

  • Online ISBN: 978-3-642-01382-9

  • eBook Packages: Medicine (German Language)

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