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Rational Use of Adjunctive Therapies: Efficacy and Efficiency

  • Andrew C. ArgentEmail author
  • Praveen Kumar
Chapter
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Abstract

The survival rates of neonates suffering from respiratory failure have improved tremendously over the last three decades. This has occurred because of general improvements in the neonatal intensive care as well as widespread use of invasive and non-invasive respiratory support. Numerous technological advances have given us newer and far better ventilators as compared to a decade ago. However, the rates of chronic lung disease (CLD) have not decreased. It is realised that although CLD has a multifactorial pathogenesis, the single most important factor responsible for occurrence of CLD is probably the endotracheal tube. Hence, all efforts are made either to avoid intubation or to minimise the duration of intubation by taking help of many adjunctive therapies. However, many of these therapies, though used very commonly, are not based on strong evidence.

Keywords

Patent Ductus Arteriosus Congenital Diaphragmatic Hernia Chronic Lung Disease Congenital Diaphragmatic Hernia Synthetic Surfactant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Division of Paediatric Critical Care and Children’s Heart DiseaseSchool of Child and Adolescent Health, University of Cape TownCape TownSouth Africa
  2. 2.Pediatric Intensive CareRed Cross War Memorial Children’s HospitalCape TownSouth Africa
  3. 3.Department of Pediatrics, Neonatal Unit, Post Graduate Institute of Medical Education and ResearchChandigarhIndia

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