Abstract
Excessive and prolonged internal soft tissue loads are one of the main factors responsible for the initiation of internal injuries that may, if ignored or untreated, escalate into chronic wounds. Since internal tissue loads cannot be measured in vivo, computational methods that incorporate the actual anatomy of the living body, are currently the best available resource for acquiring internal mechanical knowledge. In this chapter we discuss various methods that use computational modeling integrated with anatomical data, scanned by magnetic resonance imaging (MRI) in order to determine internal soft tissue loads. Specifically we will elaborate on linear and non-linear finite element (FE) methods and hyperelastic warping.
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References
Besier, T.F., Gold, G.E., Delp, S.L., Fredericson, M., Beaupre, G.S.: The influence of femoral internal and external rotation on cartilage stresses within the patellofemoral joint. J. Orthop. Res. 26, 1627–1635 (2008)
Breuls, R.G., Sengers, B.G., Oomens, C.W., Bouten, C.V., Baaijens, F.P.: Predicting local cell deformations in engineered tissue constructs: a multilevel finite element approach. J. Biomech. Eng. 124, 198–207 (2002)
Elsner, J.J., Gefen, A.: Is obesity a risk factor for deep tissue injury in patients with spinal cord injury? J. Biomech. 41, 3322–3331 (2008)
Funamoto, K., Suzuki, Y., Hayase, T., Kosugi, T., Isoda, H.: Numerical validation of MR-measurement-integrated simulation of blood flow in a cerebral aneurysm. Ann. Biomed. Eng. 37, 1105–1116 (2009)
Gallagher, R.H., Simon, B.R., Johnson, P.C., Gross, J.F.: Finite elements in biomechanics. Wiley, New York (1982)
Gefen, A.: Stress analysis of the standing foot following surgical plantar fascia release. J. Biomech. 35, 629–637 (2002)
Knecht, S., Luechinger, R., Boesiger, P., Stussi, E.: MRI-Based inverse finite element approach for the mechanical assessment of patellar articular cartilage from static compression test. Biomed. Tech. 53, 285–291 (2008)
Kumaresan, S., Yoganandan, N., Pintar, F.A., Maiman, D.J.: Finite element modeling of the cervical spine: role of intervertebral disc under axial and eccentric loads. Med. Eng. Phys. 21, 689–700 (1999)
Le, K.M., Madsen, B.L., Barth, P.W., Ksander, G.A., Angell, J.B., Vistnes, L.M.: An in-depth look at pressure sores using monolithic silicon pressure sensors. Plast. Reconstr. Surg. 74, 745–756 (1984)
Linder-Ganz, E., Shabshin, N., Itzchak, Y., Gefen, A.: Assessment of mechanical conditions in sub-dermal tissues during sitting: a combined experimental-MRI and finite element approach. J. Biomech. 40, 1443–1454 (2007)
Linder-Ganz, E., Shabshin, N., Itzchak, Y., Yizhar, Z., Siev-Ner, I., Gefen, A.: Strains and stresses in sub-dermal tissues of the buttocks are greater in paraplegics than in healthy during sitting. J. Biomech. 41, 567–580 (2008)
Makhsous, M., Lim, D., Hendrix, R., Bankard, J., Rymer, W.Z., Lin, F.: Finite element analysis for evaluation of pressure ulcer on the buttock: development and validation. IEEE Trans. Neural Syst. Rehabil. Eng. 15, 517–525 (2007)
Mooney, M.: A theory of large elastic deformation. J. Appl. Phys. 11, 582–592 (1940)
Noakes, K., Pullan, A., Bissett, I., Cheng, L.: Subject specific finite elasticity simulations of the pelvic floor. J. Biomech. 41, 3060–3065 (2008)
Papademetris, X., Sinusas, A.J., Dione, D.P., Constable, R.T., Duncan, J.S.: Estimation of 3-D left ventricular deformation from medical images using biomechanical models. IEEE Trans. Med. Imaging 21, 786–800 (2002)
Phatak, N.S., Maas, S.A., Veress, A.I., Pack, N.A., Di Bella, E.V., Weiss, J.A.: Strain measurement in the left ventricle during systole with deformable image registration. Med. Image Anal. 13, 354–361 (2009)
Phatak, N.S., Sun, Q., Kim, S.E., Parker, D.L., Sanders, R.K., Veress, A.I., Ellis, B.J., Weiss, J.A.: Noninvasive determination of ligament strain with deformable image registration. Ann. Biomed. Eng. 35, 1175–1187 (2007)
Portnoy, S., Yizhar, Z., Shabshin, N., Itzchak, Y., Kristal, A., Dotan-Marom, Y., Siev-Ner, I., Gefen, A.: Internal mechanical conditions in the soft tissues of a residual limb of a transtibial amputee. J. Biomech. 41, 1897–1909 (2008)
Rabbitt, R.D., Weiss, J.A., Christensen, G.E., Miller, M.I.: Mapping of hyperelastic deformable templates using the finite element method. Proc. SPIE (Vision Geometry IV) 2573, 252–265 (1995)
Spears, I., Miller-Young, J., Sharma, J., Ker, R., Smith, F.: The potential influence of the heel counter on internal stress during static standing: A combined finite element and positional MRI investigation. J. Biomech. 40, 2774–2780 (2007)
Stekelenburg, A., Oomens, C.W., Strijkers, G.J., Nicolay, K., Bader, D.L.: compression-induced deep tissue injury examined with magnetic resonance imaging and histology. J. App. Physiol. 100, 1946–1954 (2006)
Tanaka, E., del Pozo, R., Tanaka, M., Asai, D., Hirose, M., Iwabe, T., Tanne, K.: Three-dimensional finite element analysis of human temporomandibular joint with and without disc displacement during jaw opening. Med. Eng. Phys. 26, 503–511 (2004)
Todd, B.A., Thacker, J.G.: Three-dimensional computer model of the human buttocks, in vivo. J. Rehabil. Res. Dev. 31, 111–119 (1994)
Todd, B.A., Wang, H.: A visual basic program to pre-process mri data for finite element modeling. Comput. Biol. Med. 26, 489–495 (1996)
Veress, A.I., Gullberg, G.T., Weiss, J.A.: Measurement of strain in the left ventricle during diastole with cine-mri and deformable image registration. J. Biomech. Eng. 127, 1195–1207 (2005)
Zienkiewicz, O.C., Taylor, R.L.: The finite element method for solid and structural mechanics. Elsevier, Oxford (2005)
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Portnoy, S., Shabshin, N., Siev-Ner, I., Kristal, A., Gefen, A. (2009). MRI Integrated with Computational Methods for Determining Internal Soft Tissue Loads as Related to Chronic Wounds. In: Gefen, A. (eds) Bioengineering Research of Chronic Wounds. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-00534-3_7
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DOI: https://doi.org/10.1007/978-3-642-00534-3_7
Publisher Name: Springer, Berlin, Heidelberg
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