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MRI Integrated with Computational Methods for Determining Internal Soft Tissue Loads as Related to Chronic Wounds

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Part of the book series: Studies in Mechanobiology, Tissue Engineering and Biomaterials ((SMTEB,volume 1))

Abstract

Excessive and prolonged internal soft tissue loads are one of the main factors responsible for the initiation of internal injuries that may, if ignored or untreated, escalate into chronic wounds. Since internal tissue loads cannot be measured in vivo, computational methods that incorporate the actual anatomy of the living body, are currently the best available resource for acquiring internal mechanical knowledge. In this chapter we discuss various methods that use computational modeling integrated with anatomical data, scanned by magnetic resonance imaging (MRI) in order to determine internal soft tissue loads. Specifically we will elaborate on linear and non-linear finite element (FE) methods and hyperelastic warping.

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References

  • Besier, T.F., Gold, G.E., Delp, S.L., Fredericson, M., Beaupre, G.S.: The influence of femoral internal and external rotation on cartilage stresses within the patellofemoral joint. J. Orthop. Res. 26, 1627–1635 (2008)

    Article  Google Scholar 

  • Breuls, R.G., Sengers, B.G., Oomens, C.W., Bouten, C.V., Baaijens, F.P.: Predicting local cell deformations in engineered tissue constructs: a multilevel finite element approach. J. Biomech. Eng. 124, 198–207 (2002)

    Article  Google Scholar 

  • Elsner, J.J., Gefen, A.: Is obesity a risk factor for deep tissue injury in patients with spinal cord injury? J. Biomech. 41, 3322–3331 (2008)

    Article  Google Scholar 

  • Funamoto, K., Suzuki, Y., Hayase, T., Kosugi, T., Isoda, H.: Numerical validation of MR-measurement-integrated simulation of blood flow in a cerebral aneurysm. Ann. Biomed. Eng. 37, 1105–1116 (2009)

    Article  Google Scholar 

  • Gallagher, R.H., Simon, B.R., Johnson, P.C., Gross, J.F.: Finite elements in biomechanics. Wiley, New York (1982)

    Google Scholar 

  • Gefen, A.: Stress analysis of the standing foot following surgical plantar fascia release. J. Biomech. 35, 629–637 (2002)

    Article  Google Scholar 

  • Knecht, S., Luechinger, R., Boesiger, P., Stussi, E.: MRI-Based inverse finite element approach for the mechanical assessment of patellar articular cartilage from static compression test. Biomed. Tech. 53, 285–291 (2008)

    Article  Google Scholar 

  • Kumaresan, S., Yoganandan, N., Pintar, F.A., Maiman, D.J.: Finite element modeling of the cervical spine: role of intervertebral disc under axial and eccentric loads. Med. Eng. Phys. 21, 689–700 (1999)

    Article  Google Scholar 

  • Le, K.M., Madsen, B.L., Barth, P.W., Ksander, G.A., Angell, J.B., Vistnes, L.M.: An in-depth look at pressure sores using monolithic silicon pressure sensors. Plast. Reconstr. Surg. 74, 745–756 (1984)

    Article  Google Scholar 

  • Linder-Ganz, E., Shabshin, N., Itzchak, Y., Gefen, A.: Assessment of mechanical conditions in sub-dermal tissues during sitting: a combined experimental-MRI and finite element approach. J. Biomech. 40, 1443–1454 (2007)

    Article  Google Scholar 

  • Linder-Ganz, E., Shabshin, N., Itzchak, Y., Yizhar, Z., Siev-Ner, I., Gefen, A.: Strains and stresses in sub-dermal tissues of the buttocks are greater in paraplegics than in healthy during sitting. J. Biomech. 41, 567–580 (2008)

    Article  Google Scholar 

  • Makhsous, M., Lim, D., Hendrix, R., Bankard, J., Rymer, W.Z., Lin, F.: Finite element analysis for evaluation of pressure ulcer on the buttock: development and validation. IEEE Trans. Neural Syst. Rehabil. Eng. 15, 517–525 (2007)

    Article  Google Scholar 

  • Mooney, M.: A theory of large elastic deformation. J. Appl. Phys. 11, 582–592 (1940)

    Article  Google Scholar 

  • Noakes, K., Pullan, A., Bissett, I., Cheng, L.: Subject specific finite elasticity simulations of the pelvic floor. J. Biomech. 41, 3060–3065 (2008)

    Article  Google Scholar 

  • Papademetris, X., Sinusas, A.J., Dione, D.P., Constable, R.T., Duncan, J.S.: Estimation of 3-D left ventricular deformation from medical images using biomechanical models. IEEE Trans. Med. Imaging 21, 786–800 (2002)

    Article  Google Scholar 

  • Phatak, N.S., Maas, S.A., Veress, A.I., Pack, N.A., Di Bella, E.V., Weiss, J.A.: Strain measurement in the left ventricle during systole with deformable image registration. Med. Image Anal. 13, 354–361 (2009)

    Article  Google Scholar 

  • Phatak, N.S., Sun, Q., Kim, S.E., Parker, D.L., Sanders, R.K., Veress, A.I., Ellis, B.J., Weiss, J.A.: Noninvasive determination of ligament strain with deformable image registration. Ann. Biomed. Eng. 35, 1175–1187 (2007)

    Article  Google Scholar 

  • Portnoy, S., Yizhar, Z., Shabshin, N., Itzchak, Y., Kristal, A., Dotan-Marom, Y., Siev-Ner, I., Gefen, A.: Internal mechanical conditions in the soft tissues of a residual limb of a transtibial amputee. J. Biomech. 41, 1897–1909 (2008)

    Article  Google Scholar 

  • Rabbitt, R.D., Weiss, J.A., Christensen, G.E., Miller, M.I.: Mapping of hyperelastic deformable templates using the finite element method. Proc. SPIE (Vision Geometry IV) 2573, 252–265 (1995)

    Article  Google Scholar 

  • Spears, I., Miller-Young, J., Sharma, J., Ker, R., Smith, F.: The potential influence of the heel counter on internal stress during static standing: A combined finite element and positional MRI investigation. J. Biomech. 40, 2774–2780 (2007)

    Article  Google Scholar 

  • Stekelenburg, A., Oomens, C.W., Strijkers, G.J., Nicolay, K., Bader, D.L.: compression-induced deep tissue injury examined with magnetic resonance imaging and histology. J. App. Physiol. 100, 1946–1954 (2006)

    Article  Google Scholar 

  • Tanaka, E., del Pozo, R., Tanaka, M., Asai, D., Hirose, M., Iwabe, T., Tanne, K.: Three-dimensional finite element analysis of human temporomandibular joint with and without disc displacement during jaw opening. Med. Eng. Phys. 26, 503–511 (2004)

    Article  Google Scholar 

  • Todd, B.A., Thacker, J.G.: Three-dimensional computer model of the human buttocks, in vivo. J. Rehabil. Res. Dev. 31, 111–119 (1994)

    Google Scholar 

  • Todd, B.A., Wang, H.: A visual basic program to pre-process mri data for finite element modeling. Comput. Biol. Med. 26, 489–495 (1996)

    Article  Google Scholar 

  • Veress, A.I., Gullberg, G.T., Weiss, J.A.: Measurement of strain in the left ventricle during diastole with cine-mri and deformable image registration. J. Biomech. Eng. 127, 1195–1207 (2005)

    Article  Google Scholar 

  • Zienkiewicz, O.C., Taylor, R.L.: The finite element method for solid and structural mechanics. Elsevier, Oxford (2005)

    MATH  Google Scholar 

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Portnoy, S., Shabshin, N., Siev-Ner, I., Kristal, A., Gefen, A. (2009). MRI Integrated with Computational Methods for Determining Internal Soft Tissue Loads as Related to Chronic Wounds. In: Gefen, A. (eds) Bioengineering Research of Chronic Wounds. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-00534-3_7

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  • DOI: https://doi.org/10.1007/978-3-642-00534-3_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-00533-6

  • Online ISBN: 978-3-642-00534-3

  • eBook Packages: EngineeringEngineering (R0)

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