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Reactive Oxygen-Generating NADPH Oxidases in Plants

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Book cover Reactive Oxygen Species in Plant Signaling

Part of the book series: Signaling and Communication in Plants ((SIGCOMM))

Abstract

Reactive oxygens produced by the integral membrane protein NADPH oxidase (NOX) function in defense, development, and redox-dependent signaling. They share common structural features and are evolutionarily of ancient origin and thus ubiquitous in eukaryotes. In plants, NOX are part of a multigene family and are implicated in diverse events including innate immunity and development. Due to the fact that reactive oxygens are toxic, and in many cases short-lived, the activity of these oxidases is tightly regulated both temporally and spatially. The recent elucidation of domains for activation by calcium and Rac binding in NOX as well as its positioning on membrane lipid rafts sketches a fascinating picture of its functional dynamics. This review draws upon comparative structure–function relationships between plant and animal NOXs to portray novel aspects of their biology.

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Acknowledgement

The author acknowledges the support of the Dr. Josef Cohn MINERVA Center for Biomembrane Research.

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  1. Department of Plant Sciences, Weizmann Institute of Science, P.O.B. 26, Rehovot, 76100, Israel

    Robert Fluhr

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    Fluhr, R. (2009). Reactive Oxygen-Generating NADPH Oxidases in Plants. In: Rio, L., Puppo, A. (eds) Reactive Oxygen Species in Plant Signaling. Signaling and Communication in Plants. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-00390-5_1

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