Nasopharyngeal carcinoma (NPC) features prominently in the field of head and neck cancers (Chan et al. 2005). In centers with an active otolaryngol-ogy service, in particular those servicing NPC-endemic populations, nasopharyngeal biopsies form a significant part of a histopathologist's workload. In the vast majority of such biopsies, the diagnosis is straightforward — either benign (reactive lymphoid hyperplasia) or malignant (NPC). In a minority of cases, diagnostic challenges may arise: either a reactive process that mimics malignancy or the unusual occurrence of other forms of malignancy that histologically resemble NPC. A correct diagnosis is required for the institution of the appropriate follow-up or therapy.
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Putti, T.C., Tan, KB. (2010). Pathology of Nasopharyngeal Carcinoma. In: Lu, J.J., Cooper, J.S., Lee, A.W.M. (eds) Nasopharyngeal Cancer. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-92810-2_7
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