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Screening and Early Diagnosis of Nasopharyngeal Carcinoma

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Book cover Nasopharyngeal Cancer

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Nasopharyngeal carcinoma (NPC) is a relatively rare disease in most parts of the world, but is the most commonly diagnosed head and neck cancer in certain regions of Southeast Asia. The age-standardized incidence rate is less than 1 per 100,000 persons per year for either gender worldwide, while the annual incidence in southern China and Southeast Asia approaches 20 per 100,000 persons. In most populations, the age-standardized annual incidence rate of NPC is higher in males than in females. The male-to-female ratio is around 2–3:1 in high- and moderate-risk areas. Although it has been reported in NPC patients ranging from 4 to 91 years of age in various countries, it is uncommon under the age of 20 years (<1%). More than 80% of patients were diagnosed between 30 and 59 years of age. In high-risk areas such as Hong Kong, the NPC incidence in both genders rises sharply after the age of 20, reaching a plateau between 40 and 60 years of age. Otherwise, the age distribution curves rise late in moderate- and low-risk areas.

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Authors and Affiliations

  1. Department of Otolaryngology, College of Medicine, National Taiwan University, Taipei, Taiwan, 100, ROC

    Pei-Jen Lou

  2. Genomics Research Center, Academia Sinica, Academia Road Section 2, Nankang, Taipei, Taiwan, 115, ROC

    Wan-Lun Hsu, Yin-Chu Chien & Chien-Jen Chen

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  1. Pei-Jen Lou
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  2. Wan-Lun Hsu
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  3. Yin-Chu Chien
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Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, National University Cancer Institute of Singapore National University Health System National University of Singapore, 5 Lower Kent Ridge Road, Singapore, 119074, Republic of Singapore

    J. J. Lu (Associate Professor and Consultant, Distinguished Clinical Professor) (Associate Professor and Consultant, Distinguished Clinical Professor)

  2. Fudan University Shanghai Cancer Center, 270 Dong An Road, Shanghai, 200232, P.R. China

    J. J. Lu (Associate Professor and Consultant, Distinguished Clinical Professor) (Associate Professor and Consultant, Distinguished Clinical Professor)

  3. Department of Radiation Oncology, Maimonides Cancer Center, 6300 Eighth Avenue, Brooklyn, NY, 11220, USA

    J. S. Cooper (Professor and Chairman) (Professor and Chairman)

  4. Department of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong SAR, P.R. China

    A. W. M. Lee

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Lou, PJ., Hsu, WL., Chien, YC., Chen, CJ. (2010). Screening and Early Diagnosis of Nasopharyngeal Carcinoma. In: Lu, J.J., Cooper, J.S., Lee, A.W.M. (eds) Nasopharyngeal Cancer. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-92810-2_5

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  • DOI: https://doi.org/10.1007/978-3-540-92810-2_5

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