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Molecular Signaling Pathways in Nasopharyngeal Cancer

  • Chapter
Nasopharyngeal Cancer

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Nasopharyngeal carcinoma (NPC) is a unique type of head and neck malignancy that shows a clear regional and racial prevalence. It occurs most commonly in Asians who inhabit in the Southern Chinese provinces and Southeast Asia (Ma and Cao 2009). The biological behavior of NPC differs significantly from other types of squamous cell carcinoma of the head and neck, which are abbreviated here as SCCHN: NPC has the highest propensity of regional and distant metastases when compared with SCCHN. At the same time, NPC is more sensitive to ionizing radiation and chemotherapy.

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Authors and Affiliations

  1. Department of Radiation Therapy, 875 Blake Wilbur Dr, MC 5847, Stanford, CA, 94350-5847, USA

    Quynh-Thu Le

  2. Department of Radiation Oncology, National University Cancer Institute, National University Health System, National University of Singapore, 5 Lower Kent Ridge Road, Singapore, 119074, Republic of Singapore

    Jiade J. Lu

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Editors and Affiliations

  1. Department of Radiation Oncology, National University Cancer Institute of Singapore National University Health System National University of Singapore, 5 Lower Kent Ridge Road, Singapore, 119074, Republic of Singapore

    J. J. Lu (Associate Professor and Consultant, Distinguished Clinical Professor) (Associate Professor and Consultant, Distinguished Clinical Professor)

  2. Fudan University Shanghai Cancer Center, 270 Dong An Road, Shanghai, 200232, P.R. China

    J. J. Lu (Associate Professor and Consultant, Distinguished Clinical Professor) (Associate Professor and Consultant, Distinguished Clinical Professor)

  3. Department of Radiation Oncology, Maimonides Cancer Center, 6300 Eighth Avenue, Brooklyn, NY, 11220, USA

    J. S. Cooper (Professor and Chairman) (Professor and Chairman)

  4. Department of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong SAR, P.R. China

    A. W. M. Lee

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Le, QT., Lu, J.J. (2010). Molecular Signaling Pathways in Nasopharyngeal Cancer. In: Lu, J.J., Cooper, J.S., Lee, A.W.M. (eds) Nasopharyngeal Cancer. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-92810-2_3

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