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Concurrent Chemotherapy-Enhanced Radiation: Trials and Conclusions

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Nasopharyngeal Cancer

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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When Al-Sarraf et al. (1996) presented the preliminary results of the U. S. Intergroup 0099 Trial at the plenary session of the 1996 Annual Meeting of the American Society of Clinical Oncology (ASCO), it signaled the advent of a new era in head and neck oncology and a paradigm shift in the role of chemotherapy as an adjunct to radiation therapy (RT) in the curative management of head and neck cancer, nasopharyn-geal cancer (NPC) in particular. Today, concurrent chemoradiation therapy is considered a standard of care for all patients with locally advanced NPC worldwide (NCCN 2008; Chan and Felip 2008).

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  1. Department of Radiation Oncology, Division of Clinical Trials and Epidemiological Sciences, The Humphrey Oei Institute of Cancer Research, National Cancer Center, 11 Hospital Drive, Singapore, 169610, Republic of Singapore

    Joseph Wee

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Editors and Affiliations

  1. Department of Radiation Oncology, National University Cancer Institute of Singapore National University Health System National University of Singapore, 5 Lower Kent Ridge Road, Singapore, 119074, Republic of Singapore

    J. J. Lu (Associate Professor and Consultant, Distinguished Clinical Professor) (Associate Professor and Consultant, Distinguished Clinical Professor)

  2. Fudan University Shanghai Cancer Center, 270 Dong An Road, Shanghai, 200232, P.R. China

    J. J. Lu (Associate Professor and Consultant, Distinguished Clinical Professor) (Associate Professor and Consultant, Distinguished Clinical Professor)

  3. Department of Radiation Oncology, Maimonides Cancer Center, 6300 Eighth Avenue, Brooklyn, NY, 11220, USA

    J. S. Cooper (Professor and Chairman) (Professor and Chairman)

  4. Department of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong SAR, P.R. China

    A. W. M. Lee

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Wee, J. (2010). Concurrent Chemotherapy-Enhanced Radiation: Trials and Conclusions. In: Lu, J.J., Cooper, J.S., Lee, A.W.M. (eds) Nasopharyngeal Cancer. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-92810-2_13

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