The histological classification (WHO) of brain tumors sorts them according to their resemblance to a specific cell lineage, yielding glial tumors (gliomas or oligodendrogliomas), neuronal neoplasms (central neurocytoma, ganglioglioma, neuroblastoma), or tumors derived from ependymal cells (ependymoma). Among these, the most aggressive glioma, the glioblastoma multiforme (grade IV), has the distinctive features of palisading or geographic necrosis and conspicuous microvascular hyperplasia in addition to marked cellular pleomorphism. Glioblastoma multiforme offers a poor prognosis, even after complete treatment and resection.
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© 2009 Springer-Verlag Berlin Heidelberg
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Gil-Perotín, S., García-Verdugo, J.M., Álvarez-Buylla, A. (2009). Oncogenesis vs. Neurogenesis. In: Identification and Characterization of Neural Progenitor Cells in the Adult Mammalian Brain. Advances in Anatomy, Embryology and Cell Biology, vol 203. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-88719-5_4
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DOI: https://doi.org/10.1007/978-3-540-88719-5_4
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