Zusammenfassung
Die Wirbelsäule entsteht aus der Chorda dorsalis. Die Chorda bildet den späteren Gallertkern der Bandscheiben. Bei Geburt ist die Wirbelsäule in ihrer Anlage voll entwickelt. Vor dem 4. Lebensjahr ist die Bandscheibe bis in den äußeren Faserring vaskularisiert. Nach dem 4. Lebensjahr erfolgt die Ernährung der Bandscheibe ausschließlich per Diffusion, Gefäße sind dann nicht mehr nachweisbar. Die Wirbelsäule durchläuft einen natürlichen Alterungsprozess. Schon mit dem 30. Lebensjahr treten beim Menschen physiologischerweise degenerative Veränderungen der Bandscheibe auf. Der Nucl. pulposus hat einen hohen Proteoglykan- und damit einen hohen Wassergehalt. Bei der kindlichen Bandscheibe liegt der Wassergehalt bei 90%, dieser nimmt im Alter auf ca. 70% ab (Gower u. Pedrini 1969). Er ist von einem kräftigen Anulus fibrosus und von Poren enthaltenden kartilaginären Endplatten umgeben. Nach innen verlaufen die Fasern in einem Winkel von ca. 60°, wodurch die Wirbelsäule eine wesentliche Stabilität für Rotationsbewegungen erhält (Krismer et al. 1997). Der intradiskale Ruhedruck einer intakten Bandscheibe beträgt ca. 500 kPa, kann aber in Abhängigkeit von der Belastung bis auf 2300 kPa ansteigen (Eysel et al. 2000, Wilke et al. 2001). Unter Belastung verliert die Bandscheibe Wasser, der osmotische Druck nimmt umgekehrt proportional zur Belastung zu (Kolditz et al. 1985).
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Turnbull DK, Shepherd DB (2003) Post-dural puncture headache: pathogenesis, prevention and treatment. Br J Anaesth 91:718– 729 (Review)
Scanlon GC, Moeller-Bertram T, Romanowsky SM, Wallace MS (2007) Cervical transforaminal epidural steroid injections: more dangerous than we think? Spine 32: 1249–1256
Scavone BM, Wong CA, Sullivan JT et al (2004) Efficacy of a prophylactic epidural blood patch in preventing post dural puncture headache in parturients after inadvertent dural puncture. Anesthesiology 101: 1422–1427
Schaufele MK, Hatch L, Jones W (2006) Interlaminar versus transforaminal epidural injections for the treatment of symptomatic lumbar intervertebral disc herniations. Pain Physician 9: 361– 366
Schmidt A, Nolte H (1992) Subdurale und epidurale Hämatome nach rückenmarksnahen Regionalanästhesien. Anaesthesist 41: 276– 284 (Review)
Schneider M, Ettlin T, Kaufmann M, Schumacher P, Urwyler A, Hampl K, von Hochstetter A (1993) Transient neurologic toxicity after hyperbaric subarachnoid anesthesia with 5% lidocaine. Anesth Analg 76: 1154–1157
Scott DB, Hibbard BM (1990) Serious non-fatal complications associated with extradural block in obstetric practice. Br J Anaesth 64: 537–541
Sellheim H (1905) Die Herabsetzung der Empfindlichkeit der Bauchdecken und des Peritoneum parietale durch perineurale Injektion anästhesierender Lösungen an die Stämme der Nervi intercostales, des Subcostalis, des Ileohypogastricus und des Ileoinguinalis. Verhandlungen der Deutschen Gesellschaft für Gynäkologie (13.-17.06.1905), 11. Versammlung: 176–179
Sendi P, Bregenzer T, Zimmerli W (2008) Spinal epidural abscess in clinical practice. QJM 101: 1–12
Shetty SK, Nelson EN, Lawrimore TM, Palmer WE (2007) Use of gadolinium chelate to confirm epidural needle placement in patients with an iodinated contrast reaction. Skeletal Radiol 36: 301– 307
Sicard MA (1901) Les injections médicamenteuses extra-durales par voie sacro-coccygienne. C R Soc Biol (Paris) 53: 396–398
Siddiq F, Chowfin A, Tight R et al (2004) Medical vs surgical management of spinal epidural abscess. Arch Intern Med 164: 2409– 2412
Siegers A, Board P (2002) Amiodarone used in successful resuscitation after near-fatal flecainide overdose. Resuscitation 53: 105– 108
Simpson D, Curran MP, Oldfield V, Keating GM (2005) Ropivacaine: a review of its use in regional anaesthesia and acute pain management. Drugs 65: 2675–2717
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Slipman CW, Issac Z (2001) The role of diagnostic selective nerve root blocks in the management of spinal pain. Pain Physician 4: 214– 226
Slipman CW, Chow DW, Lenrow DA et al (2002) Dysphonia associated with epidural steroid injection: a case report. Arch Phys Med Rehabil 83: 1309–1310
Smuck M, Fuller BJ, Yoder B, Huerta J (2007) Incidence of simultaneous epidural and vascular injection during lumbosacral transforaminal epidural injections. Spine J 7: 79–82
Somayaji HS, Saifuddin A, Casey AT, Briggs TW (2005) Spinal cord infarction following therapeutic computed tomography-guided left L2 nerve root injection. Spine 30: E106–108
Staal JB, de Bie R, de Vet HCW, Hildebrandt J, Nelemans P (2008) Injection therapy for subacute and chronic low-back pain (Review). Cochrane Database Syst Rev (3): CD001824, pp 1–51
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Stalcup ST, Crall TS, Gilula L, Riew KD (2006) Influence of needle-tip position on the incidence of immediate complications in 2,217 selective lumbar nerve root blocks. Spine J 6: 170–176
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Stitz MY, Sommer HM (1999) Accuracy of blind versus fluoroscopically guided caudal epidural injection. Spine 24: 1371–1376
Sudlow C, Warlow C (2002) Epidural blood patching for preventing and treating post-dural puncture headache. Cochrane Database Syst Rev (2): CD001791
Sullivan WJ, Willick SE, Chira-Adisai W (2000) Incidence of intravascular uptake in lumbar spinal injection procedures. Spine 25: 481– 486
Symons JA, Palmer GM (2008) Neuropathic pain and foot drop related to nerve injury after short duration surgery and caudal analgesia. Clin J Pain 24: 647–649
Tachihara H, Sekiguchi M, Kikuchi S, Konno S (2008) Do corticosteroids produce additional benefit in nerve root infiltration for lumbar disc herniation? Spine 33: 743–747
Tajima T, Omata S, Kuramochi E et al (1976) Selective lumbosacral radiculography and block. Seikei Geka (Orthopedic Surgery) 27: 1053–1062
Teske W, Zirke S, Trippe C, Krämer J et al (2009) Die epidurale Injektionsbehandlung mit Lokalanästhetikum versus Kortison beim chronischen lumbalen Nervenwurzelkompressionssyndrom: eine prospektive Studie. Z Orthop Unfall 147: 199–204
Theodoridis T (2007) Injektionstherapie an der Wirbelsäule ohne Bildsteuerung. Orthopäde 36: 73–86
Theodoridis T, Krämer J (2006) Injektionstherapie an der Wirbelsäule. Manual und Atlas, 1. Aufl. Thieme, Stuttgart
Theodoridis T, Mamarvar R, Krämer J, Wiese M, Teske W (2009) Einstichwinkel bei der epidural-perineuralen Injektion an der Lendenwirbelsäule. (Angle of needle position for the epidural-perineural injection at the lumbar spine) Z Orthop Unfall 147: 65–68
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Böhm, B., Lange, A., Eckardt, A., Scheufler, KM. (2011). Therapeutische Möglichkeiten – interventionelle und operative Verfahren. In: Praxis LWS-Erkrankungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-88507-8_5
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