The MammoSite intracavitary brachytherapy balloon applicator was designed as a simplified alternative to multicatheter interstitial brachytherapy. The ease of use of this brachytherapy system has resulted in MammoSite intracavitary brachytherapy becoming one of the most commonly employed methods of APBI. This chapter reviews technical considerations for MammoSite, including physics and dosimetry considerations, implantation techniques, and postimplant evaluation. The clinical experience and results obtained with this technique are also reviewed.
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References
Arthur D (2003) Accelerated partial breast irradiation: a change in treatment paradigm for early stage breast cancer. J Surg Oncol 84(4):185–191
Astrahan MA, Jozsef G, Streeter OE (2004) Optimization of MammoSite therapy. Int J Radiat Oncol Biol Phys 58(1):220–232
Beitsch P, Vicini F, et al. (2008) Recurrence and survival in the American Society of Breast Surgeons MammoSite RTS Registry Trial. Int J Radiat Oncol Biol Phys 72(1):S2–S3
Benitez PR, Keisch ME, et al. (2007) Five-year results: the initial clinical trial of MammoSite balloon brachytherapy for partial breast irradiation in early-stage breast cancer. Am J Surg 194(4):456–462
Cheng CW, Mitra R, et al. (2005) Dose perturbations due to contrast medium and air in MammoSite treatment: an experimental and Monte Carlo study. Med Phys 32(7):2279–2287
Cuttino LW, Keisch M, et al. (2008) Multi-institutional experience using the MammoSite radiation therapy system in the treatment of early-stage breast cancer: 2-year results. Int J Radiat Oncol Biol Phys 71(1):107–114
Dempsey JF, Williams JA, Stubbs JB, et al. (1998) Dosimetric properties of a novel brachytherapy balloon applicator for the treatment of malignant brain-tumor resection-cavity margins. Int J Radiat Oncol Biol Phys 42(2):421–429
Dickler A, Kirk M, Choo J, et al. (2004) Treatment volume and dose optimization of the MammoSite breast brachytherapy applicator. Int J Radiat Oncol Biol Phys 59(2):469–474
Dickler A, Kirk MC, et al. (2005) The MammoSite breast brachytherapy applicator: a review of technique and outcomes. Brachytherapy 4(2):130–136
Dowlatshahi K, Snider HC, Gittleman MA, et al. (2004) Early experience with balloon brachyther-apy for breast cancer. Arch Surg 139:603–608
Edmundson GK, Vicini FA, Chen P Y, et al. (2002) Dosimetric characteristics of the MammoSite RTS, a new breast brachytherapy applicator. Int J Radiat Oncol Biol Phys 52(4):1132–1139
Evans SB, Kaufman SA, et al. (2006) Persistent seroma after intraoperative placement of MammoSite for accelerated partial breast irradiation: incidence, pathologic anatomy, and contributing factors. Int J Radiat Oncol Biol Phys 65(2):333–339
Haffty BG, Vicini FA, et al. (2008) Timing of chemotherapy after MammoSite radiation therapy system breast brachytherapy registry trial. Int J Radiat Oncol Biol Phys 72(5):1441–1448
Harper JL, Jenrette JM, et al. (2005) Acute complications of MammoSite brachytherapy: a single institution's initial clinical experience. Intl J Radiat Oncol Biol Phys 61(1):169–174
Keisch M (2005) MammoSite. Expert Rev Med Devices 2(4):387–394
Keisch M, Vicini F, Kuske R, et al. (2003) Initial clinical experience with the MammoSite breast brachytherapy applicator in women with early-stage breast cancer treated with breast-conserving therapy. Int J Radiat Oncol Biol Phys 55(2):289–293
Keisch M, Vicini F, Scroggins T, et al. (2005) Thirty-nine month results with the MammoSite applicator: details regarding cosmesis, toxicity, and local control in partial breast irradiation. Int J Radiat Oncol Biol Phys 63:56 (abstract)
Keisch M, Vicini F, et al. (2009) American Society of Breast Surgeons Mammosite RTS registry trial: ductal carcinoma in-situ subset analysis: four year data in 194 treated lesions. Am J Surg (in press)
Kirk MC, Hsi WC, et al. (2004) Dose perturbation induced by radiographic contrast inside brachytherapy balloon applicators. Med Phys 31(5):1219–1224
Major T, Niehoff P, et al. (2006) Dosimetric comparisons between high dose rate interstitial and MammoSite balloon brachytherapy for breast cancer. Radiother Oncol 79(3):321–328
Prestidge B, Sadeghi A, et al. (2006) Local control of early stage breast cancer using MammoSite HDR Brachytherapy. Int J Radiat Oncol Biol Phys 66(3 suppl 1):S215
Richards GM, Berson AM, Rescigno J, et al. (2004) Acute toxicity of high-dose-rate intracavitary brachytherapy with the MammoSite applicator in patients with early-stage breast cancer. Ann Surg Oncol 11(8):739–746
Spurlock JP, Kuske RR, McKinnon WMP, et al. (2000) A caprine breast model for testing a novel balloon brachytherapy device. OJVR 4(1):106–123
Vicini F, Beitsch P, Quiet C, et al. (2005) First analysis of patient demographics, technical repro-ducibility, cosmesis, and early toxicity. Cancer 104(6):1138–1148
Wazer DE, Lowther D, Boyle T, et al. (2001) Clinically evident fat necrosis in women treated with high-dose-rate brachytherapy alone for early-stage breast cancer. Int J Radiat Oncol Biol Phys 50:107–111
Zannis VJ, Walker LC, Barclay-White B, et al. (2003) Postoperative ultrasound-guided percutaneous placement of a new breast brachytherapy balloon catheter. Am J Surg 186(4):383–385
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Keisch, M., Vicini, F.A. (2009). The MammoSite Technique for Accelerated Partial Breast Irradiation. In: Wazer, D.E., Arthur, D.W., Vicini, F.A. (eds) Accelerated Partial Breast Irradiation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-88006-6_14
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DOI: https://doi.org/10.1007/978-3-540-88006-6_14
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