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Plant Relationships pp 157–172Cite as

The cAMP Signaling and MAP Kinase Pathways in Plant Pathogenic Fungi

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Part of the book series: The Mycota ((MYCOTA,volume 5))

Abstract

All eukaryotic organisms must be able to sense and respond to extracellular signals for regulating various developmental and differentiation processes. The cyclic AMP (cAMP) signaling and mitogen-activated protein (MAP) kinase pathways are among the best studied signal transduction pathways in eukaryotes. The key components of the cAMP-PKA pathway include the adenylate cyclase (AC) and regulatory and catalytic subunits of protein kinase A (PKA). In Saccharomyces cerevisiae, both small GTPase Ras and trimeric G-protein Gpa2 Gα function upstream from the cAMP-PKA pathway. Adenylate cyclase is activated by Gα subunits in Schizosaccharomyces pombe and the model filamentous fungus Neurospora crassa (Kays et al. 2000). Although there are no experimental data to determine whether AC is activated by Ras or heterotrimeric G-proteins in most ascomycetous fungal pathogens, phenotype analyses of related mutants and pharmacological studies often suggest the involvement of Ga in the cAMP-PKA pathway (Gronover et al. 2001; Liu and Dean 1997).

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  1. Department of Botany and Plant Pathology, Purdue University, West Lafayette, IN, 47907, USA

    Rahim Mehrabi, Xinhua Zhao, Yangseon Kim & Jin-Rong Xu

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  1. Rahim Mehrabi
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  2. Xinhua Zhao
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Correspondence to Rahim Mehrabi .

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  1. Phytopathologie und Pflanzenschutz, Naturwissenschaftliche Fakultät III Institut für Agrar- und Ernährungswissenschaften, Ludwig-Wucherer-Str. 2, 06099, Halle (Saale), Germany

    Holger B. Deising

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Mehrabi, R., Zhao, X., Kim, Y., Xu, JR. (2009). The cAMP Signaling and MAP Kinase Pathways in Plant Pathogenic Fungi. In: Deising, H.B. (eds) Plant Relationships. The Mycota, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-87407-2_8

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