Probabilistic Anatomo-Functional Parcellation of the Cortex: How Many Regions?
Understanding brain structure and function entails the inclusion of anatomical and functional information in a common space, in order to study how these different informations relate to each other in a population of subjects. In this paper, we revisit the parcellation model and explicitly combine anatomical features, i.e. a segmentation of the cortex into gyri, with a functional information under the form of several cortical maps, which are used to further subdivide the gyri into functionally consistent regions. A probabilistic model is introduced, and the parcellation model is estimated using a Variational Bayes approach. The number of regions in the model is validated based on cross-validation. It is found that about 250 patches of cortex can be delineated both in the left and right hemisphere based on this procedure.
KeywordsGaussian Mixture Model Functional Information fMRI Data Cortical Surface Replicator Dynamic
- 9.Devlin, J.T., Poldrack, R.A.: In praise of tedious anatomy. Neuroimage 37, 1033–41; discussion 1050–8 (2007)Google Scholar
- 11.Thyreau, B., Thirion, B., Flandin, G., et al.: Anatomo-functional description of the brain: A probabilistic approach. In: ICASSP, pp. V–V (2006) Google Scholar
- 13.Perrot, M., Rivière, D., Mangin, J.F.: Identifying cortical sulci from localizations, shape and local organization. In: 5th ISBI, Paris, France, pp. 420–423 (2008)Google Scholar