Motion Correction in Respiratory Gated Cardiac PET/CT Using Multi-scale Optical Flow
Respiratory motion is a source of degradation in positron emission tomography. As the patients cannot hold breath during the PET acquisition, spatial blurring and motion artifacts are unavoidable which may lead to wrong quantification of the data. A solution based on respiratory-gating and optical flow based correction of the PET data is proposed. This includes deformation of the CT data for accurate attenuation and listmode based reconstruction. All methods are applied to real patient data and are evaluated with respect to three criteria.
KeywordsPositron Emission Tomography Attenuation Correction Respiratory Motion Motion Correction Compute Tomography Data
- 1.Erdi, Y., Nehmeh, S., Pan, T., Pevsner, A., Rosenzweig, K., Mageras, G., Yorke, E.D., Schoder, H., Hsiao, W., Squire, O.D., Vernon, P., Ashman, J.B., Mostafavi, H., Larson, S.M., Humm, J.L.: The CT motion quantitation of lung lesions and its impact on PET-measured SUVs. J. Nucl. Med. 45(8), 1287–1292 (2004)Google Scholar
- 2.Osman, M.M., Cohade, C., Nakamoto, Y., Marshall, L., Leal, J., Wahl, R.: Clinically significant inaccurate localization of lesions with PET/CT: frequency in 300 patients. J. Nucl. Med. 44(2), 240–243 (2003)Google Scholar
- 4.Dawood, M., Büther, F., Jiang, X., Schäfers, K.P.: Respiratory Motion Correction in 3D PET Data with Advanced Optical Flow Algorithms. In: IEEE Trans. Med. Imaging (in press, 2008)Google Scholar
- 13.Erdi, Y.E., Nehmeh, S.A., Mulnix, T., Humm, J.L., Watson, C.C.: PET performance measurements for an LSO-based combined PET/CT scanner using the national electrical manufacturers association nu 2-2001 standard. J. Nucl. Med. 45(5), 813–821 (2004)Google Scholar