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Myelodysplasia

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Abstract

By definition, all children with myelodysplasia have some form of spinal abnormality at birth, and most will develop some degree of spinal deformity by 10 years of age.

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References

  1. Ajeena AW, Hall IE, Emans JB (1993) Functional outcomes in myelodysplasia following spinal fusion. Orthop Transac 17:107

    Google Scholar 

  2. Akbarnia BA, Marks DS, Boachie-Adjei O et al (2005) Dual growing rod technique for the treatment of progressive early-onset scoliosis: a multicenter study. Spine 30:S46–S57

    Article  PubMed  Google Scholar 

  3. Allen BL Jr, Ferguson RL (1979) The operative treatment of myelomeningocele spinal deformity - 1979. Orthop Clin North Am 10:845–862

    PubMed  Google Scholar 

  4. Allen BL Jr, Ferguson RL (1982) The Galveston technique for L rod instrumentation of the scoliotic spine. Spine 7: 276–284

    Article  PubMed  Google Scholar 

  5. Asher M, Olson J (1983) Factors affecting the ambulatory status of patients with spina bifida cystica. J Bone Joint Surg Am 65:350–356

    PubMed  CAS  Google Scholar 

  6. Banta JV, Hamada JS (1976) Natural history of the kyphotic deformity in myelomeningocele. J Bone Joint Surg Am 58:279

    Google Scholar 

  7. Banta JV, Park SM (1983) Improvement in pulmonary function in patients having combined anterior and posterior spine fusion for myelomeningocele scoliosis. Spine 8: 765–770

    Article  PubMed  CAS  Google Scholar 

  8. Banta JV (1990) Combined anterior and posterior fusion for spinal deformity in myelomeningocele. Spine 15:946–952

    Article  PubMed  CAS  Google Scholar 

  9. Banta JV, Bonanni C, Prebluda J (1993) Latex anaphylaxis during spinal surgery in children with myelomeningocele. Dev Med Child Neurol 35:543–548

    Article  PubMed  CAS  Google Scholar 

  10. Banta JV (1996) The orthopaedic history of spinal dysraphism. I: the early history. Dev Med Child Neurol 38:848–854

    Article  PubMed  CAS  Google Scholar 

  11. Banit DM, Iwinski HJ Jr., Talwalker V et al (2001)Posterior spinal fusion in paralytic scoliosis and myelomingocele. J Pediatr Orthop 21:117-125

    Article  PubMed  CAS  Google Scholar 

  12. Barson AJ (1970) The vertebral level of termination of the spinal cord during normal and abnormal development. J Anat 106:489–497

    PubMed  CAS  Google Scholar 

  13. Basobas L, Mardjetko S, Hammerberg K et al (2003) Selective anterior fusion and instrumentation for the treatment of neuromuscular scoliosis. Spine 28:S245–S248

    Article  PubMed  Google Scholar 

  14. Benson ER, Thomson JD, Smith BG et al (1998) Results and morbidity in a consecutive series of patients undergoing spinal fusion for neuromuscular scoliosis. Spine 23:2308–2317; discussion 2318

    Article  PubMed  CAS  Google Scholar 

  15. Birmingham PK, Suresh S (1999) Latex allergy in children: diagnosis and management. Indian J Pediatr 66:717–724

    Article  PubMed  CAS  Google Scholar 

  16. Boachie-Adjei O, Lonstein JE, Winter RB et al (1989) Management of neuromuscular spinal deformities with Luque segmental instrumentation. J Bone Joint Surg Am 71:548–562

    PubMed  CAS  Google Scholar 

  17. Bol KA, Collins JS, Kirby RS (2006) Survival of infants with neural tube defects in the presence of folic acid fortification. Pediatrics 117:803–813

    Article  PubMed  Google Scholar 

  18. Brinker MR, Rosenfeld SR, Feiwell E et al (1994) Myelomeningocele at the sacral level. Long-term outcomes in adults. J Bone Joint Surg Am 76:1293–1300

    PubMed  CAS  Google Scholar 

  19. Brock DJ, Scrimgeour JB (1972) Early prenatal diagnosis of anencephaly. Lancet 2:1252–1253

    Article  PubMed  CAS  Google Scholar 

  20. Brock DJ, Sutcliffe RG (1972) Alpha-fetoprotein in the antenatal diagnosis of anencephaly and spina bifida. Lancet 2:197–199

    Article  PubMed  CAS  Google Scholar 

  21. Brophy JD, Sutton LN, Zimmerman RA et al (1989) Magnetic resonance imaging of lipomyelomeningocele and tethered cord. Neurosurgery 25:336–340

    Article  PubMed  CAS  Google Scholar 

  22. Bruner JP, Tulipan N, Paschall RL et al (1999) Fetal surgery for myelomeningocele and the incidence of shuntdependent hydrocephalus. JAMA 282:1819–1825

    Article  PubMed  CAS  Google Scholar 

  23. Campbell R Jr, Smith M, Allen W et al (1980) The treatment of secondary thoracic insufficiency syndrome of myelomeningocele by a hybrid VEPTR“Eiffel Tower” construct with s-hook iliac crest pedestal fixation. Pediatric Orthopaedic Society of North America Annual Meeting, Albuquerque, NM

    Google Scholar 

  24. Carrillo T, Cuevas M, Munoz T et al (1986) Contact urticaria and rhinitis from latex surgical gloves. Contact Dermatitis 15:69–72

    Article  PubMed  CAS  Google Scholar 

  25. Carstens C, Paul K, Niethard FU et al (1991) Effect of scoliosis surgery on pulmonary function in patients with myelomeningocele. J Pediatr Orthop 11:459–464

    Article  PubMed  CAS  Google Scholar 

  26. Carstens C, Koch H, Brocai DR et al (1996). Development of pathological lumbar kyphosis in myelomeningocele. J Bone Joint Surg Am 78: 945–950

    Article  CAS  Google Scholar 

  27. Carter CO, Roberts JA (1967) The risk of recurrence after two children with central-nervous-system malformations. Lancet 1:306–308

    Article  PubMed  CAS  Google Scholar 

  28. Cochrane DD, Finley C, Kestle J et al (2000) The patterns of late deterioration in patients with transitional lipomyelomeningocele. Eur J Pediatr Surg 10(Suppl 1):13–17

    Article  PubMed  Google Scholar 

  29. Copp AJ (1993) Neural tube defects. Trends Neurosci 16: 381–383

    Article  PubMed  CAS  Google Scholar 

  30. Cotter AM, Daly SF (2005) Neural tube defects: is a decreasing prevalence associated with a decrease in severity? Eur J Obstet Gynecol Reprod Biol 119:161–163

    Article  PubMed  Google Scholar 

  31. Cremer R, Hoppe A, Kleine-Diepenbruck U et al (1998) Longitudinal study on latex sensitization in children with spina bifida. Pediatr Allergy Immunol 9:40–43

    Article  PubMed  CAS  Google Scholar 

  32. Cuckle H (1994) Screening for neural tube defects. In: Brock G, Marsh J (eds) Neural tube defects, CIBA Foundatiion Symposium. Wiley, Chichester, pp 253–269

    Google Scholar 

  33. De Wals P, Tairou F, Van Allen M et al (2007) Reduction in neural-tube defects after folic acid fortification in Canada. N Engl J Med 357:135–142

    Article  PubMed  Google Scholar 

  34. DeWald RL, Faut MM (1979) Anterior and posterior spinal fusion for paralytic scoliosis. Spine 4:401–409

    Article  PubMed  CAS  Google Scholar 

  35. Di Rocco C, Rende M (1989) Chiari malformations. In: Raimondi AJ, Choux M, DiRocco C (eds) The pediatric spine: developmental anomalies. Springer, New York, pp 57–90

    Chapter  Google Scholar 

  36. Dirks PB (1995) The genetic basis of neurosurgical disorders. In: Youmans JR (ed) Neurological surgery. WB Saunders, Philadelphia, pp 811–828

    Google Scholar 

  37. Dormans JP, Templeton J, Schreiner MS et al (1997) Intraoperative latex anaphylaxis in children: classification and prophylaxis of patients at risk. J Pediatr Orthop 17:622–625

    PubMed  CAS  Google Scholar 

  38. Drummond D, Guadagni J, Keene JS et al (1984) Interspinous process segmental spinal instrumentation. J Pediatr Orthop 4:397–404

    Article  PubMed  CAS  Google Scholar 

  39. Drummond D, Breed AL, Narechania R (1985) Relationship of spine deformity and pelvic obliquity on sitting pressure distributions and decubitus ulceration. J Pediatr Orthop 5:396–402

    Article  PubMed  CAS  Google Scholar 

  40. Eberle C (1988) Failure of fixation after segmental spinal instrumentation without arthrodesis in the management of paralytic scoliosis. J Bone Joint Surg Am 70: 696–703

    PubMed  CAS  Google Scholar 

  41. Ferguson RL, Allen BL Jr (1983) Staged correction of neuromuscular scoliosis. J Pediatr Orthop 3:555–562

    Article  PubMed  CAS  Google Scholar 

  42. Flippin MA, Canale S, Akbarnia BA (2008) Spinal deformity in myelomeningocele. In: Kim D, Betz R (eds) Surgery of the pediatric spine. Thieme, New York, pp 467–477

    Google Scholar 

  43. Furman L, Mortimer JC (1994) Menarche and menstrual function in patients with myelomeningocele. Dev Med Child Neurol 36:910–917

    Article  PubMed  CAS  Google Scholar 

  44. Gau YL, Lonstein JE, Winter RB et al (1991) Luque– Galveston procedure for correction and stabilization of neuromuscular scoliosis and pelvic obliquity: a review of 68 patients. J Spinal Disord 4:399–410

    Article  PubMed  CAS  Google Scholar 

  45. Geiger F, Parsch D, Carstens C (1999) Complications of scoliosis surgery in children with myelomeningocele. Eur Spine J 8:22–26

    Article  PubMed  CAS  Google Scholar 

  46. Gentili A, Lima M, Ricci G et al (2006) Secondary prevention of latex allergy in children: analysis of results. Pediatr Med Chir 28:83–90 20 Myelodysplasia 265

    PubMed  CAS  Google Scholar 

  47. Gerber AC, Jorg W, Zbinden S et al (1989) Severe intraoperative anaphylaxis to surgical gloves: latex allergy, an unfamiliar condition. Anesthesiology 71:800–802

    Article  PubMed  CAS  Google Scholar 

  48. Gold M, Swartz JS, Braude BM et al (1991) Intraoperative anaphylaxis: an association with latex sensitivity. J Allergy Clin Immunol 87:662–666

    Article  PubMed  CAS  Google Scholar 

  49. Green N (2002) Folic acid supplementation and prevention of birth defects. J Nutr 132 (8 Suppl):2356S–2360S

    PubMed  CAS  Google Scholar 

  50. Guille JT, Sarwark JF, Sherk HH et al (2006) Congenital and developmental deformities of the spine in children with myelomeningocele. J Am Acad Orthop Surg 14:294–302

    PubMed  Google Scholar 

  51. Gullestad HP, Bretteville G, Lundar T et al (1993) Tissue expansion for the treatment of myelomeningocele. Case report. Scand J Plast Reconstr Surg Hand Surg 27: 149–151

    Article  PubMed  CAS  Google Scholar 

  52. Herman JM, McLone DG, Storrs BB et al (1993) Analysis of 153 patients with myelomeningocele or spinal lipoma reoperated upon for a tethered cord. Presentation, management and outcome. Pediatr Neurosurg 19: 243–249

    Article  PubMed  CAS  Google Scholar 

  53. Hoffer MM, Feiwell E, Perry R et al (1973) Functional ambulation in patients with myelomeningocele. J Bone Joint Surg Am 55:137–148

    PubMed  CAS  Google Scholar 

  54. Holmes NM, Nguyen HT, Harrison MR et al (2001) Fetal intervention for myelomeningocele: effect on postnatal bladder function. J Urol 166:2383–2386

    Article  PubMed  CAS  Google Scholar 

  55. Holzman R S, Sockin S (1990) Hypotension, flushing, and bronchospasm in myelodysplasia patients (abstract). Anesthesiology 73:1123

    Google Scholar 

  56. Holzman RS (1993) Latex allergy: an emerging operating room problem. Anesth Analg 76:635–641

    Article  PubMed  CAS  Google Scholar 

  57. Hoppenfield S (1967) Congenital kyphosis in myelomeningocele. J Bone Joint Surg 49:276

    Google Scholar 

  58. Johnson MP, Gerdes M, Rintoul N et al (2006) Maternalfetal surgery for myelomeningocele: neurodevelopmental outcomes at 2 years of age. Am J Obstet Gynecol 194: 1145–1150; discussion 1150–1142

    Article  PubMed  Google Scholar 

  59. Kahanovitz N, Duncan JW (1981) The role of scoliosis and pelvic obliquity on functional disability in myelomeningocele. Spine 6:494–497

    Article  PubMed  CAS  Google Scholar 

  60. Karlin L, Zimbler S (1990) The association of spondylolisthesis and myelomeningocele. The Pediatric Orthopaedic Society of North America, Annual Meeting, San Francisco, CA

    Google Scholar 

  61. Karol LA, Richards BS, Prejean E et al (1993) Hemodynamic instability of myelomeningocele patients during anterior spinal surgery. Dev Med Child Neurol 35:261–267

    Article  PubMed  CAS  Google Scholar 

  62. Kelly KJ, Kurup V, Zacharisen M et al (1993) Skin and serologic testing in the diagnosis of latex allergy. J Allergy Clin Immunol 91:1140–1145

    Article  PubMed  CAS  Google Scholar 

  63. Kennedy D, Koren G (1998) Valproic acid use in psychiatry: issues in treating women of reproductive age. J Psychiatry Neurosci 23:223–228

    PubMed  CAS  Google Scholar 

  64. Korenromp MJ, van Gool JD, Bruinese HW et al (1986) Early fetal leg movements in myelomeningocele. Lancet 1: 917–918

    Article  PubMed  CAS  Google Scholar 

  65. Kwittken PL, Becker J, Oyefara B et al (1992) Latex hypersensitivity reactions despite prophylaxis. Allergy Proc 13: 123–127

    Article  PubMed  CAS  Google Scholar 

  66. Lawrence K (1967) Clinical and ethical considerations of alpha-fetoprotein for early prenatal diagnosis of neural tube malformations. Dev Med Child Neurol 16 (Suppl 32): 117

    Google Scholar 

  67. Letts M, Rathbone D, Yamashita T et al (1992) Soft Boston orthosis in management of neuromuscular scoliosis: a preliminary report. J Pediatr Orthop 12:470–474

    Article  PubMed  CAS  Google Scholar 

  68. Leynadier F, Pecquet C, Dry J (1989) Anaphylaxis to latex during surgery. Anaesthesia 44:547–550

    Article  PubMed  CAS  Google Scholar 

  69. Lindseth RE GG (1988) One stage anterior transpedicu lar and unilateral fusion for congenital scoliosis. Orthop Trans 12:184

    Google Scholar 

  70. Lindseth RE (1994) Myelomeningocele spine. In: Weinstein W (ed) The pediatric spine: principles and practice. Raven, New York, pp 1043–1067

    Google Scholar 

  71. Lindseth R (2001) Myelomeningocele. In: Morrissy RT, Weinstein SL (eds) Lovell and Winter’s pediatric orthopaedics. Lippincott Williams & Wilkins, Philadelphia, pp 601–632

    Google Scholar 

  72. Locke MD, Sarwark JF (1996) Orthopaedic aspects of myelodysplasia in children. Curr Opin Pediatr 8:65–67

    Article  PubMed  CAS  Google Scholar 

  73. Luciano R, Velardi F (1989) Epidemiology and clues to the etiology of neural tube defects. In: Raimondi A, Choux M, DiRocco C (eds) The pediatric spine I: development and the dysraphic state. Springer, New York, pp 126–147

    Chapter  Google Scholar 

  74. Luque ER (1982) Segmental spinal instrumentation for correction of scoliosis. Clin Orthop Relat Res 163: 192–198

    PubMed  Google Scholar 

  75. Lyons A, Petrucelli, RJ (1978) Medicine, an illustrated history. Harry N. Abrams, New York

    Google Scholar 

  76. Mackel JL Lindseth RE (1975) Scoliosis and myelodysplasia. J Bone Joint Surg Am 57:1031

    Google Scholar 

  77. Mayfield JK (1981) Severe spine deformity in myelodysplasia and sacral agenesis: an aggressive surgical approach. Spine 6:498–509

    Article  PubMed  CAS  Google Scholar 

  78. Mazon A, Nieto A, Estornell F et al (1997) Factors that influence the presence of symptoms caused by latex allergy in children with spina bifida. J Allergy Clin Immunol 99: 600–604

    Article  PubMed  CAS  Google Scholar 

  79. Mazur J, Menelaus MB, Dickens DR et al (1986) Efficacy of surgical management for scoliosis in myelomeningocele: correction of deformity and alteration of functional status. J Pediatr Orthop 6:568–575

    Article  PubMed  CAS  Google Scholar 

  80. McLone DG, Herman JM, Gabrieli AP et al (1990) Tethered cord as a cause of scoliosis in children with a myelomeningocele. Pediatr Neurosurg 16:8–13

    Article  PubMed  Google Scholar 

  81. McLone DG (2003) Tethered cord in spina bifida. In: Lipotak G (ed) Evidence-based practice in spina bifida: developing a research agenda. Spina Bifida Association of America, Washington, D.C

    Google Scholar 

  82. McMaster MJ (1987) Anterior and posterior instrumentation and fusion of thoracolumbar scoliosis due to myelomeningocele. J Bone Joint Surg Am 69:20–25

    CAS  Google Scholar 

  83. Meeropol E, Kelleher R, Bell S et al (1990) Allergic reactions to rubber in patients with myelodysplasia. N Engl J Med 323:1072

    PubMed  CAS  Google Scholar 

  84. Meuli M, Meuli-Simmen C, Hutchins GM et al (1997) The spinal cord lesion in human fetuses with myelomeningocele: implications for fetal surgery. J Pediatr Surg 32: 448–452

    Article  PubMed  CAS  Google Scholar 

  85. Miladi LT, Ghanem IB, Draoui MM et al (1997) Iliosacral screw fixation for pelvic obliquity in neuromuscular scoliosis. A long-term follow-up study. Spine 22:1722–1729

    Article  PubMed  CAS  Google Scholar 

  86. Mish M (ed) (1997) Merriam webster’s collegiate dictionary. Merriam-Webster, Springfield 266 L. I. Karlin

    Google Scholar 

  87. Moneret-Vautrin DA, Laxenaire MC, Bavoux F (1990) Allergic shock to latex and ethylene oxide during surgery for spinal bifida. Anesthesiology 73:556–558

    Article  PubMed  CAS  Google Scholar 

  88. Muller EB, Nordwall A (1992) Prevalence of scoliosis in children with myelomeningocele in western Sweden. Spine 17:1097–1102

    Article  PubMed  CAS  Google Scholar 

  89. Muller EB, Nordwall A, von Wendt L (1992) Influence of surgical treatment of scoliosis in children with spina bifida on ambulation and motoric skills. Acta Paediatr 81:173–176

    Article  PubMed  CAS  Google Scholar 

  90. Muller EB, Nordwall A (1994) Brace treatment of scoliosis in children with myelomeningocele. Spine 19:151–155

    Article  PubMed  CAS  Google Scholar 

  91. Muller EB, Nordwall A, Oden A (1994) Progression of scoliosis in children with myelomeningocele. Spine 19: 147–150

    Article  PubMed  CAS  Google Scholar 

  92. Nguyen DH, Burns MW, Shapiro GG et al (1991) Intraoperative cardiovascular collapse secondary to latex allergy. J Urol 146:571–574

    PubMed  CAS  Google Scholar 

  93. Nieto A, Mazon A, Pamies R et al (2002) Efficacy of latex avoidance for primary prevention of latex sensitization in children with spina bifida. J Pediatr 140:370–372

    Article  PubMed  Google Scholar 

  94. Nolden MT, Sarwark JF, Vora A et al (2002) A kyphectomy technique with reduced perioperative morbidity for myelomeningocele kyphosis. Spine 27:1807–1813

    Article  PubMed  Google Scholar 

  95. Noonan K (2006) Myelominingocele. In: Morrissy RT, Weinstein SL (eds) Lovell and Winter’s pediatric orthopaedics. Lippincott Williams and Wilkins, Philadelphia, pp 605–647

    Google Scholar 

  96. Okamoto GA, Lamers JV, Shurtleff DB (1983) Skin breakdown in patients with myelomeningocele. Arch Phys Med Rehabil 64:20–23

    PubMed  CAS  Google Scholar 

  97. Osebold WR, Mayfield JK, Winter RB et al (1982) Surgical treatment of paralytic scoliosis associated with myelomeningocele. J Bone Joint Surg Am 64:841–856

    PubMed  CAS  Google Scholar 

  98. Pang D, Wilberger JE Jr (1982) Tethered cord syndrome in adults. J Neurosurg 57:32–47

    Article  PubMed  CAS  Google Scholar 

  99. Paonessa KJ, Zide B, Errico T, Engler GL (1991) Using tissue expanders in spinal surgery for deficient soft tissue or postirradiation cases. Spine 16:S324–S327

    Article  PubMed  CAS  Google Scholar 

  100. Parasini P, Greggi T, DiSilvestre M (eds) (2002) Surgical treatment of scoliosis in myelomingocele. IOS Press, Amsterdam

    Google Scholar 

  101. Parisini P, Greggi T, DiSilvestre M et al (2002) Surgical treatment of scoliosis in myelomeningocele. In: Griv TB (ed) Research into spinal deformities 4. IOS Press, Amsterdam

    Google Scholar 

  102. Parsch D, Geiger F, Brocai DR et al (2001) Surgical management of paralytic scoliosis in myelomeningocele. J Pediatr Orthop 10:10–17

    CAS  Google Scholar 

  103. Pecquet C, Leynadier F, Dry J (1990) Contact urticaria and anaphylaxis to natural latex. J Am Acad Dermatol 22:631–633

    Article  PubMed  CAS  Google Scholar 

  104. Peelle MW, Lenke LG, Bridwell KH et al (2006) Comparison of pelvic fixation techniques in neuromuscular spinal deformity correction: Galveston rod versus iliac and lumbosacral screws. Spine 31:2392–2398; discussion 2399

    Article  PubMed  Google Scholar 

  105. Pierz K, Banta J, Thomson J et al (2000) The effect of tethered cord release on scoliosis in myelomeningocele. J Pediatr Orthop 20:362–365

    PubMed  CAS  Google Scholar 

  106. Piggott H (1980) The natural history of scoliosis in myelodysplasia. J Bone Joint Surg Am 62-B:54–58

    CAS  Google Scholar 

  107. Proos LA, Dahl M, Ahlsten G et al (1996) Increased perinatal intracranial pressure and prediction of early puberty in girls with myelomeningocele. Arch Dis Child 75:42–45

    Article  PubMed  CAS  Google Scholar 

  108. Rang M (2000) The story of orthopaedics. W.B. Saunders, Philadelphia

    Google Scholar 

  109. Raycroft JF, Curtis B (1972) Spinal curvature in myelomeningocele: natural history and etiology. Symposium on myelomeningocele. C.V. Mosby, Hartford

    Google Scholar 

  110. Reigel D (1982) Spina bifida. In: Section of Pediatric Neurosurgery of the American Association of Neurological Surgeons (ed) Pediatric neurosurgery: surgery of the developing nervous system. Grune and Stratton, New York, pp 23–47

    Google Scholar 

  111. Reigel D (1983) Tethered spinal cord. In: Humphrey R (ed) Concepts in pediatric neurosurgery. Karger, Basil, p 142

    Google Scholar 

  112. Rodgers WB, Frim DM, Emans JB (1997) Surgery of the spine in myelodysplasia. An overview. Clin Orthop Relat Res:19–35

    Google Scholar 

  113. Rodgers WB, Williams MS, Schwend RM et al (1997) Spinal deformity in myelodysplasia. Correction with posterior pedicle screw instrumentation. Spine 22:2435–2443

    Article  PubMed  CAS  Google Scholar 

  114. Rotenstein D, Reigel DH (1996) Growth hormone treatment of children with neural tube defects: results from 6 months to 6 years. J Pediatr 128:184–189

    Article  PubMed  CAS  Google Scholar 

  115. Samuelsson L, Eklof O (1988) Scoliosis in myelomeningocele. Acta Orthop 59:122–127

    CAS  Google Scholar 

  116. Samuelsson L, Skoog M (1988) Ambulation in patients with myelomeningocele: a multivariate statistical analysis. J Pediatr Orthop 8:569–575

    Article  PubMed  CAS  Google Scholar 

  117. Sarwark JF (1996) Spina bifida. Pediatr Clin North Am 43:1151–1158

    Article  PubMed  CAS  Google Scholar 

  118. Schoenmakers MA, Gulmans VA, Gooskens RH et al (2005) Spinal fusion in children with spina bifida: influence on ambulation level and functional abilities. Eur Spine J 14:415–422

    Article  PubMed  CAS  Google Scholar 

  119. Schut L, Bruce DA, Sutton LN (1983) The management of the child with a lipomyelomeningocele. Clin neurosurg 30:464–476

    PubMed  CAS  Google Scholar 

  120. Setlock MA, Cotter TP, Rosner D (1993) Latex allergy: failure of prophylaxis to prevent severe reaction. Anesth Analg 76:650–652

    Article  PubMed  CAS  Google Scholar 

  121. Shurtleff DB, Goiney R, Gordon LH et al (1976) Myelodysplasia: the natural history of kyphosis and scoliosis. A preliminary report. Dev Med Child Neurol Suppl: 126–133

    Google Scholar 

  122. Shurtleff DB, Lemire RJ (1995) Epidemiology, etiologic factors, and prenatal diagnosis of open spinal dysraphism. Neurosurg Clin N Am 6:183–193

    PubMed  CAS  Google Scholar 

  123. Slater JE (1989) Rubber anaphylaxis. N Engl J Med 320:1126–1130

    Article  PubMed  CAS  Google Scholar 

  124. Slater JE, Mostello LA, Shaer C et al (1990) Type I hypersensitivity to rubber. Ann Allergy 65:411–414

    PubMed  CAS  Google Scholar 

  125. Slater JE (1992) Allergic reactions to natural rubber. Ann Allergy 68:203–209

    PubMed  CAS  Google Scholar 

  126. Smithells RW, Nevin NC, Seller MJ et al (1983) Further experience of vitamin supplementation for prevention of neural tube defect recurrences. Lancet 1:1027–1031

    Article  PubMed  CAS  Google Scholar 

  127. Sockin SM, Young MC (1991) Preoperative prophylaxis of latex anaphylaxis (Abstract). J Allergy Clin Immunol 87: 269 20 Myelodysplasia 267

    Article  Google Scholar 

  128. Sponseller PD, Young AT, Sarwark JF et al (1999) Anterior only fusion for scoliosis in patients with myelomeningocele. Clin Orthop Relat Res 364:117–124

    Article  PubMed  Google Scholar 

  129. Stanitski CL, Stanitski DF, LaMont RL (1994) Spon dylolisthesis in myelomeningocele. J Pediatr Orthop 14: 586–591

    Article  PubMed  CAS  Google Scholar 

  130. Stark A, Saraste H (1993) Anterior fusion insufficient for scoliosis in myelomeningocele: 8 children 2–6 years after the Zielke operation. Acta Orthop Scand 64:22–24

    Article  PubMed  CAS  Google Scholar 

  131. Steinbok P, Irvine B, Cochrane DD et al (1992) Long-term outcome and complications of children born with meningomyelocele. Childs Nerv Syst 8:92–96

    Article  PubMed  CAS  Google Scholar 

  132. Stevens DB, Beard C (1989) Segmental spinal instrumentation for neuromuscular spinal deformity. Clin Orthop Relat Res:164–168

    Google Scholar 

  133. Stoll C, Alembik Y, Dott B (2006) Are the recommendations on the prevention of neural tube defects working? Eur J Med Gen 49:461–465

    Article  CAS  Google Scholar 

  134. Sussman GL, Tarlo S, Dolovich J (1991) The spectrum of IgE-mediated responses to latex. JAMA 265:2844–2847

    Article  PubMed  CAS  Google Scholar 

  135. Sutton LN, Adzick NS, Bilaniuk LT et al (1999) Improvement in hindbrain herniation demonstrated by serial fetal magnetic resonance imaging following fetal surgery for myelomeningocele. JAMA 282:1826–1831

    Article  PubMed  CAS  Google Scholar 

  136. Swank M, Dias L (1992) Myelomeningocele: a review of the orthopaedic aspects of 206 patients treated from birth with no selection criteria. Dev Med Child Neurol 34:1047–1052

    Article  PubMed  CAS  Google Scholar 

  137. Toriello HV, Higgins JV (1983) Occurrence of neural tube defects among first-, second-, and third-degree relatives of probands: results of a United States study. Am J Med Genet 15:601–606

    Article  PubMed  CAS  Google Scholar 

  138. Tosi LL, Slater JE, Shaer C et al (1993) Latex allergy in spina bifida patients: prevalence and surgical implications. J Pediatr Orthop 13:709–712

    Article  PubMed  CAS  Google Scholar 

  139. Trivedi J, Thomson JD, Slakey JB et al (2002) Clinical and radiographic predictors of scoliosis in patients with myelomeningocele. J Bone Joint Surg Am 84-A:1389–1394

    PubMed  Google Scholar 

  140. Trollmann R, Dorr HG, Strehl E et al (1996) Growth and pubertal development in patients with meningomyelocele: a retrospective analysis. Acta Paediatr 85:76–80

    Article  PubMed  CAS  Google Scholar 

  141. Trollmann R, Strehl E, Wenzel D et al (1998) Arm span, serum IGF-1 and IGFBP-3 levels as screening parameters for the diagnosis of growth hormone deficiency in patients with myelomeningocele - preliminary data. Eur J Pediatr 157:451–455

    Article  PubMed  CAS  Google Scholar 

  142. Trollmann R, Strehl E, Wenzel D et al (2000) Does growth hormone (GH) enhance growth in GH-deficient children with myelomeningocele? J Clin Endocrinol Metab 85:2740–2743

    Article  PubMed  CAS  Google Scholar 

  143. Trollmann R, Langhans B, Strehl E et al (2001) A crosssectional study of dehydroepiandrosterone sulfate in prepubertal children with myelomeningocele. Horm Res 56:19–24

    Article  PubMed  CAS  Google Scholar 

  144. Tulipan N, Sutton LN, Bruner JP et al (2003) The effect of intrauterine myelomeningocele repair on the incidence of shunt-dependent hydrocephalus. Pediatr Neurosurg 38:27–33

    Article  PubMed  Google Scholar 

  145. Turjanmaa K, Reunala T, Rasanen L (1988) Comparison of diagnostic methods in latex surgical glove contact urticaria. Contact Derm 19:241–247

    Article  PubMed  CAS  Google Scholar 

  146. Wai EK, Young NL, Feldman BM et al (2005) The relationship between function, self-perception, and spinal deformity: Implications for treatment of scoliosis in children with spina bifida. J Pediatr Orthop 25: 64–69

    PubMed  Google Scholar 

  147. Wald NJ, Cuckle H, Brock JH et al (1977) Report of UK collaborative study of alpha-fetoprotein in relation to neural tube defects: maternal serum-alpha-fetoprotein measurement in antenatal screening for anencephaly and spina bifida in early pregnancy. Lancet 1:1323–1332

    PubMed  CAS  Google Scholar 

  148. Ward WT, Wenger DR, Roach JW (1989) Surgical correction of myelomeningocele scoliosis: a critical appraisal of various spinal instrumentation systems. J Pediatr Orthop 9: 262–268

    Article  PubMed  CAS  Google Scholar 

  149. Wild A, Haak H, Kumar M et al (2001) Is sacral instrumentation mandatory to address pelvic obliquity in neuromuscular thoracolumbar scoliosis due to myelomeningocele? Spine 26:E325–E329

    Article  PubMed  CAS  Google Scholar 

  150. Winston K, Hall J, Johnson D et al (1977) Acute elevation of intracranial pressure following transection of non-functional spinal cord. Clin Orthop Relat Res:41–44

    Google Scholar 

  151. Yazici M, Asher MA, Hardacker JW (2000) The safety and efficacy of Isola–Galveston instrumentation and arthrodesis in the treatment of neuromuscular spinal deformities. J Bone Joint Surg Am 82:524–543

    PubMed  CAS  Google Scholar 

  152. Yen IH, Khoury MJ, Erickson JD et al (1992) The changing epidemiology of neural tube defects. United States, 1968–1989. Am J Dis Child 146:857–861

    PubMed  CAS  Google Scholar 

  153. Zerin JM, McLaughlin K, Kerchner S (1996) Latex allergy in patients with myelomeningocele presenting for imaging studies of the urinary tract. Pediatr Radiol 26:450–454

    Article  PubMed  CAS  Google Scholar 

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Karlin, L.I. (2011). Myelodysplasia. In: Akbarnia, B.A., Yazici, M., Thompson, G.H. (eds) The Growing Spine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-85207-0_20

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