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Großzellige und aggressive B-Zell Lymphome

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Pathologie

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Zusammenfassung

Diffuse großzellige B-Zell Lymphome (DLBCL) sind seit ihrer ursprünglichen Klassifikation als heterogene Gruppe mehrerer Entitäten definiert worden. Seither wurden nach morphologischen, klinischen und molekularen Kriterien in der WHO Klassifikation verschiedene Entitäten abgegrenzt und auch in der Gruppe der nach Entitäten nicht weiter unterscheidbaren Formen des Lymphknotenbefalls unterschiedliche molekulare Ableitungen von Keimzentrumszellen oder aktivierten B-Zellen definiert. In diesem Kapitel sind alle Entitäten des DLBCL mit primärem Lymphknotenbefall, die Burkitt Lymphome, sowie Varianten mit intermediären morphologischen oder molekulargenetischen Befunden und nicht organtypische Entitäten der DLBCL behandelt und in ihrer Abgrenzung dargestellt, sodass eine klinisch und therapeutisch relevante Differenzialdiagnose ermöglicht wird.

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Authors and Affiliations

  1. Pathologisches Institut der Ludwig-Maximilians-Universität München, München, Deutschland

    Prof. Dr. Andreas Rosenwald & Prof. Dr. Martina Rudelius

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  1. Prof. Dr. Andreas Rosenwald
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  2. Prof. Dr. Martina Rudelius
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Correspondence to Andreas Rosenwald .

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  1. der Universität Würzburg, Pathologisches Institut der Universität Würzburg, Würzburg, Bayern, Germany

    Hans Konrad Müller-Hermelink

  2. Medizinische Hochschule Hannover (MHH) Inst. Pathologie, Hannover, Germany

    Hans H. Kreipe

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Rosenwald, A., Rudelius, M. (2019). Großzellige und aggressive B-Zell Lymphome. In: Müller-Hermelink, H., Kreipe, H. (eds) Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-85184-4_23

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  • DOI: https://doi.org/10.1007/978-3-540-85184-4_23

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