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A Stochastic Model of the Interleukin (IL)-1β Network

  • Johnny Kelsey
  • Brian Henderson
  • Rob Seymour
  • Andy Hone
Part of the Lecture Notes in Computer Science book series (LNCS, volume 5132)

Abstract

The interleukin-1β network is a primary mediator of the inflammatory response and plays an important role in many immunological processes. A Markov chain model of the network is presented, along with results from iteration over the stochastic matrix. The stationary distribution of the model is analysed.

Keywords

IL-1β interleukin-1β Markov process cytokine network stochastic matrix 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Johnny Kelsey
    • 1
  • Brian Henderson
    • 2
  • Rob Seymour
    • 3
  • Andy Hone
    • 4
  1. 1.CoMPLEXUniversity College London 
  2. 2.Division of Microbial DiseasesUniversity College London 
  3. 3.CoMPLEX/Department of MathematicsUniversity College London 
  4. 4.IMSASUniversity of Kent 

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