The initial cases of DM in German literature were fatal [1–3], but recoveries were soon observed [4, 5]. In the precorticosteroid era, the largest review, of 153 cases with adequate follow-up, determined a mortality rate of 61% [6]. Most surviving patients had permanent sequelae (e.g., muscle atrophy, joint contractures, and calcinosis). Later, in more studies of noncorticosteroid-treated patients, the mortality rate improved to 37%, and 33% of patients had good recoveries [7–9]. However, the prognosis of DM was significantly worse in older patients.
In contrast, case reports of “spontaneous” recoveries are documented in classic DM [4–6] and amyopathic DM [10].
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References
Hepp P. Über Pseudo-trichinose, eine besondere Form von acuter parenchymatose Polymyosi-tis. Berl Klin Wochenschr 1887; 24: 297, 332.
Unverricht H. Über eine eigenthümliche Form von akuter Muskelentzündung mit einem der Trichinose ähnelnden Krankheitsbilde. Müncher Med Wochenschr 1887; 34: 488–492.
Wagner E. Fall einer seltnen Muskelkrankheit. Dtsch Arch Heilk 1863; 4: 282–283.
Lewy B. Zur Lehre von der primären acuten Polymyositis. Berlin Klin Wochenschr 1893; 30: 475–477.
Unverricht H. Dermatomyositis acuta. Dtsch Med Wochenschr 1891; 17: 41–44.
Schuermann H. Zur Klinik und Pathogenese der Dermatomyositis (Polymyositis). Arch Der-mat Syph (Wien) 1939; 178: 414–468.
Wedgwood RJ, Cook CD, Cohen J. Dermatomyositis. Report of 26 cases in children with a discussion of endocrine therapy in 13. Pediatrics 1953; 12: 447–466.
Everett MA, Curtis AC. Dermatomyositis. A review of nineteen cases in adolescents and children. Arch Intern Med 1957; 100: 70–76.
Winkelmann RK, Mulder DW, Lambert EH, et al. Course of dermatomyositis—polymyositis: comparison of untreated and cortisone-treated patients. Mayo Clin Proc 1968; 43: 545–556.
Jordan JR, Paruthi S, Pichardo RO, et al. Spontaneously remitting dermatomyositis. JEADV 2004; 18: 495–498.
Agarwal SK, Monach PA, Docken W P, et al. Characterization of relapses in adult idiopathic inflammatory myopathies. Clin Rheumatol 2006; 25(4): 476–481.
Benbassat J, Geffel D, Larholt K, et al. Prognostic factors in polymyositis/dermatomyositis: a computer-assisted analysis of 92 cases. Arthritis Rheum 1985; 28: 249–255.
Love LA, Leff RL, Fraser DD, et al. A new approach to the classification of idiopathic inflammatory myopathy: myositis-specific autoantibodies define useful homogeneous patient groups. Medicine 1991; 70: 360–374.
Maugars YM, Berthelot JMM, Abbas AA, et al. Long term prognosis of 69 patients with der-matomyositis or polymyositis 1996. Clin Exp Rheumatol 1996; 14: 263–274.
Marie I, Hatron P-Y, Levesque H, et al. Influence of age on characteristics of polymyositis and dermatomyositis in adults. Medicine 1999; 78: 139–147.
Danko K, Ponyi A, Constantin T, et al. Long-term survival of patients with idiopathic inflammatory myopathies according to clinical features. A longitudinal study of 162 cases. Medicine 2004; 83: 35–42.
Falcini F, Trapani S, Ermini M, et al. Systemic vasculitis in juvenile dermatomyositis: a fatal case. Clin Exp Rheumatol 1995; 13: 531–532.
Takeda T, Fujisaku A, Jodo S, et al. Fatal vascular occlusion in juvenile dermatomyositis. Ann Rheum Dis 1998; 57: 172–176.
Mautner GH, Grossman ME, Silvers DN, et al. Epidermal necrosis as a predictive sign of malignancy in adult dermatomyositis. Cutis 1998; 61: 190–194.
Basset-Seguin N, Roujeau JC, Gherardi R, et al. Prognostic factors and predictive signs of malignancy in adult dermatomyositis. A study of 32 cases. Arch Dermatol 1990; 126: 633–637.
Xue L, Chen X, Chen S. Prognostic factors of dermatomyositis: analysis of 119 cases. Chin J Intern Med 1997; 36: 32–35.
Chen YJ, Wu C Y, Shen JL. Predicting factors of malignancy in dermatomyositis and polymy-ositis: a case-control study. Br J Dermatol 2001; 144: 825–831.
Medsger TA, Robinson H, Masi AT. Factors affecting survivorship in polymyositis. A lifetable study of 124 patients. Arthritis Rheum 1971; 14: 249–258.
Hochberg MC, Feldman D, Stevens MB. Adult onset polymyositis—dermatomyositis: an analysis of clinical and laboratory factors and survival in 76 patients with a review of the literature. Semin Arthritis Rheum 1986; 15: 168–191.
Marie I, Hachulla E, Hatron P-Y, et al. Polymyositis and dermatomyositis: short term and long term outcome, and predictive factors of prognosis. J Rheumatol 2001; 28: 2230–2237.
Sultan SM, Ioannou Y, Moss K, et al. Outcome in patients with idiopathic inflammatory myositis: morbidity and mortality. Rheumatology 2002; 41: 22–26.
Huber A, Feldman BM. Long-term outcomes in juvenile dermatomyositis: how did we get here and where are we going? Curr Rheumatol Rep 2005; 7: 441–446.
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(2009). Evolution and prognosis of Dermatomyositis. In: Dermatomyositis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-79313-7_42
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