Abstract
Porous β-tricalcium phosphate (β-TCP) ceramic scaffolds with axially oriented macropore and random micropore were produced by selective laser sintering (SLS) process. Microstructure parameters including pore size, pore size distribution and interconnectivity were quantified by microcomputed tomography. Compressive mechanical properties were tested. The porosity of sintered scaffolds was over 60%. The range of average compressive modulus and ultimate strength was 24.38∼30.64MPa and 1.64∼2.35MPa, respectively. Dog bone marrow stromal cells (BMSCs) were seeded in the prepared scaffolds. Cell proliferation and osteogenic differentiation on the scaffolds were evaluated with the alkaline phosphatase (ALP) activity and osteocalcin (OCN) content.
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© 2008 Springer-Verlag Berlin Heidelberg
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Lin, L., Zhang, J., Zhao, L., Tong, A., Sun, J., Hu, Q. (2008). Effect of microstructure on the mechanical properties and biology performance of bone tissue scaffolds using selective laser sintering. In: Peng, Y., Weng, X. (eds) 7th Asian-Pacific Conference on Medical and Biological Engineering. IFMBE Proceedings, vol 19. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-79039-6_23
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DOI: https://doi.org/10.1007/978-3-540-79039-6_23
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-79038-9
Online ISBN: 978-3-540-79039-6
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