Abstract
Human population migration, adaptation, and admixture have a chaotic and mostly undocumented history, but we are at the cusp of an era where we will be able to unlock these records from our genomes. An admixed individual’s genome with ancestors from isolated populations is a mosaic of chromosomal blocks, each following the statistical properties of variation seen in those populations. By analyzing polymorphisms in the admixed individual against those seen in representatives from the populations, we can infer the ancestral source of the individual’s haploblocks. Several methods have emerged recently that use SNPs as a basis for variation to infer the ancestral population composition of admixed individuals.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Author information
Authors and Affiliations
Editor information
Rights and permissions
Copyright information
© 2008 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Sundquist, A., Fratkin, E., Do, C.B., Batzoglou, S. (2008). Effects of Genetic Divergence in Identifying Ancestral Origin Using HAPAA. In: Vingron, M., Wong, L. (eds) Research in Computational Molecular Biology. RECOMB 2008. Lecture Notes in Computer Science(), vol 4955. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-78839-3_36
Download citation
DOI: https://doi.org/10.1007/978-3-540-78839-3_36
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-78838-6
Online ISBN: 978-3-540-78839-3
eBook Packages: Computer ScienceComputer Science (R0)