Skip to main content
SpringerLink
Log in

DW-MRI for Disease Characterization in the Abdomen

  • Chapter
Diffusion-Weighted MR Imaging

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Summary

DW-MRI has been widely applied for the evaluation of abdominal malignancies. In the liver, the use of DW-MRI is increasing, both for lesion detection as well as for lesion characterization. However, the potential for using DW-MRI to characterize tumours of the bile duct, pancreas, kidneys and other abdominal organs continues to evolve. Disease characterization relies on comparing the relative signal attenuation of tissues on images obtained at different b-values and also on the quantitative apparent diffusion coefficient of the tissue of interest. In this chapter, we summarize the application of DW-MRI for the purpose of tumour characterization in the abdomen, enabling the differentiation of benign from malignant disease, and providing novel information which may be of diagnostic or prognostic value.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • ACS (2009) Cancer Facts and Figures 2009, American Cancer Society, Atlanta

    Google Scholar 

  • Bakir B, Salmaslioglu A et al (2009) Diffusion weighted MR imaging of pancreatic islet cell tumors. Eur J Radiol

    Google Scholar 

  • Bruegel M, Holzapfel K et al (2008) Characterization of focal liver lesions by ADC measurements using a respiratory triggered diffusion-weighted single-shot echo-planar MR imaging technique. Eur Radiol 18:477–485

    Article  PubMed  Google Scholar 

  • Chan JH, Tsui EY et al (2001a) Diffusion-weighted MR imaging of the liver: distinguishing hepatic abscess from cystic or necrotic tumor. Abdom Imaging 26:161–165

    Article  CAS  PubMed  Google Scholar 

  • Chan JH, Tsui EY et al (2001b) MR diffusion-weighted imaging of kidney: differentiation between hydronephrosis and pyonephrosis. Clin Imaging 25:110–113

    Article  CAS  PubMed  Google Scholar 

  • Chow LC, Bammer R et al (2003) Single breath-hold diffusion-weighted imaging of the abdomen. J Magn Reson Imaging 18:377–382

    Article  PubMed  Google Scholar 

  • Cova M, Squillaci E et al (2004) Diffusion-weighted MRI in the evaluation of renal lesions: preliminary results. Br J Radiol 77:851–857

    Article  CAS  PubMed  Google Scholar 

  • Fattahi R, Balci NC et al (2009) Pancreatic diffusion-weighted imaging (DWI): comparison between mass-forming focal pancreatitis (FP), pancreatic cancer (PC), and normal pancreas. J Magn Reson Imaging 29:350–356

    Article  PubMed  Google Scholar 

  • Filippi CG, Edgar MA et al (2001) Appearance of meningiomas on diffusion-weighted images: correlating diffusion constants with histopathologic findings. AJNR Am J Neuroradiol 22:65–72

    CAS  PubMed  Google Scholar 

  • Goshima S, Kanematsu M et al (2009) Hepatic hemangioma: correlation of enhancement types with diffusion-weighted MR findings and apparent diffusion coefficients. Eur J Radiol 70:325–330

    Article  PubMed  Google Scholar 

  • Gourtsoyianni S, Papanikolaou N et al (2008) Respiratory gated diffusion-weighted imaging of the liver: value of apparent diffusion coefficient measurements in the differentiation between most commonly encountered benign and malignant focal liver lesions. Eur Radiol 18:486–492

    Article  PubMed  Google Scholar 

  • Guo AC, Cummings TJ et al (2002) Lymphomas and highgrade astrocytomas: comparison of water diffusibility and histologic characteristics. Radiology 224:177–183

    Article  PubMed  Google Scholar 

  • Haaga JR, Lanzieri CF et al (2003) MR imaging of the whole body. Mosby, St.Louis, MO

    Google Scholar 

  • Ho CL, Dehdashti F et al (1996) FDG-PET evaluation of indeterminate pancreatic masses. J Comput Assist Tomogr 20: 363–369

    Article  CAS  PubMed  Google Scholar 

  • Holzapfel K, Rummeny E et al (2007) Diffusion-weighted MR imaging of hepatic abscesses: possibility of different apparent diffusion coefficient (ADC)-values in early and mature abscess formation. Abdom Imaging 32:538–539

    Article  PubMed  Google Scholar 

  • Ichikawa T, Erturk SM et al (2006) High-B-value diffusion-weighted MRI in colorectal cancer. AJR Am J Roentgenol 187:181–184

    Article  PubMed  Google Scholar 

  • Ichikawa T, Erturk SM et al (2007) High-b value diffusion-weighted MRI for detecting pancreatic adenocarcinoma: preliminary results. AJR Am J Roentgenol 188:409–414

    Article  PubMed  Google Scholar 

  • Ichikawa T, Haradome H et al (1998) Diffusion-weighted MR imaging with a single-shot echoplanar sequence: detection and characterization of focal hepatic lesions. AJR Am J Roentgenol 170:397–402

    CAS  PubMed  Google Scholar 

  • Ichikawa T, Haradome H et al (1999) Diffusion-weighted MR imaging with single-shot echo-planar imaging in the upper abdomen: preliminary clinical experience in 61 patients. Abdom Imaging 24:456–461

    Article  CAS  PubMed  Google Scholar 

  • Inan N, Arslan A et al (2008) Diffusion-weighted imaging in the differential diagnosis of cystic lesions of the pancreas. AJR Am J Roentgenol 191:1115–1121

    Article  PubMed  Google Scholar 

  • Irie H, Honda H et al (2002) Measurement of the apparent diffusion coefficient in intraductal mucin-producing tumor of the pancreas by diffusion-weighted echo-planar MR imaging. Abdom Imaging 27:82–87

    Article  CAS  PubMed  Google Scholar 

  • Kim S, Jain M et al (2009) T1 Hyperintense renal lesions: characterization with diffusion-weighted MR imaging versus contrast-enhanced MR imaging. Radiology 251:796–807

    Article  PubMed  Google Scholar 

  • Kim T, Murakami T et al (1999) Diffusion-weighted singleshot echoplanar MR imaging for liver disease. AJR Am J Roentgenol 173:393–398

    CAS  PubMed  Google Scholar 

  • Kim T, Murakami T et al (2001) Pancreatic mass due to chronic pancreatitis: correlation of CT and MR imaging features with pathologic findings. AJR Am J Roentgenol 177: 367–371

    CAS  PubMed  Google Scholar 

  • Koh DM, Brown G et al (2008) Detection of colorectal hepatic metastases using MnDPDP MR imaging and diffusion-weighted imaging (DWI) alone and in combination. Eur Radiol 18:903–910

    Article  CAS  PubMed  Google Scholar 

  • Koh DM, Scurr E et al (2006) Colorectal hepatic metastases: quantitative measurements using single-shot echo-planar diffusion-weighted MR imaging. Eur Radiol 16: 1898–1905

    Article  CAS  PubMed  Google Scholar 

  • Koinuma M, Ohashi I et al (2005) Apparent diffusion coefficient measurements with diffusion-weighted magnetic reso-nance imaging for evaluation of hepatic fibrosis. J Magn Reson Imaging 22:80–85

    Article  PubMed  Google Scholar 

  • Lammer J, Herlinger H et al (1985) Pseudotumorous pancreatitis. Gastrointest Radiol 10:59–67

    Article  CAS  PubMed  Google Scholar 

  • Lee SS, Byun JH et al (2008) Quantitative analysis of diffusion-weighted magnetic resonance imaging of the pancreas: usefulness in characterizing solid pancreatic masses. J Magn Reson Imaging 28:928–936

    Article  PubMed  Google Scholar 

  • Lyng H, Haraldseth O et al (2000) Measurement of cell density and necrotic fraction in human melanoma xenografts by diffusion weighted magnetic resonance imaging. Magn Reson Med 43:828–836

    Article  CAS  PubMed  Google Scholar 

  • Manenti G, Di Roma M et al (2008) Malignant renal neoplasms: correlation between ADC values and cellularity in diffusion weighted magnetic resonance imaging at 3 T. Radiol Med 113:199–213

    Article  CAS  PubMed  Google Scholar 

  • Moteki T, Horikoshi H (2006) Evaluation of hepatic lesions and hepatic parenchyma using diffusion-weighted echo-planar MR with three values of gradient b-factor. J Magn Reson Imaging 24:637–645

    Article  PubMed  Google Scholar 

  • Moteki T, Horikoshi H et al (2002) Evaluation of hepatic lesions and hepatic parenchyma using diffusion-weighted reordered turboFLASH magnetic resonance images. J Magn Reson Imaging 15:564–572

    Article  PubMed  Google Scholar 

  • Moteki T, Sekine T (2004) Echo planar MR imaging of the liver: comparison of images with and without motion probing gradients. J Magn Reson Imaging 19:82–90

    Article  PubMed  Google Scholar 

  • Muller MF, Prasad P et al (1994) Abdominal diffusion mapping with use of a whole-body echo-planar system. Radiology 190:475–478

    CAS  PubMed  Google Scholar 

  • Murakami T, Nakamura H et al (1995) Contrast-enhanced MR imaging of intrahepatic cholangiocarcinoma: pathologic correlation study. J Magn Reson Imaging 5:165–170

    Article  CAS  PubMed  Google Scholar 

  • Muraoka N, Uematsu H et al (2008) Apparent diffusion coeffi-cient in pancreatic cancer: characterization and histo-pathological correlations. J Magn Reson Imaging 27: 1302–1308

    Article  PubMed  Google Scholar 

  • Nakashima O, Kojiro M (1987) Hepatocellular carcinoma: an atlas of its pathology. Springer, Tokyo

    Google Scholar 

  • Namimoto T, Yamashita Y et al (1997) Focal liver masses: characterization with diffusion-weighted echo-planar MR imaging. Radiology 204:739–744

    CAS  PubMed  Google Scholar 

  • Nasu K, Kuroki Y et al (2004) Diffusion-weighted single shot echo planar imaging of colorectal cancer using a sensitivity-encoding technique. Jpn J Clin Oncol 34:620–626

    Article  PubMed  Google Scholar 

  • Nasu K, Kuroki Y et al (2006) Hepatic metastases: diffusion-weighted sensitivity-encoding versus SPIO-enhanced MR imaging. Radiology 239:122–130

    Article  PubMed  Google Scholar 

  • Neff CC, Simeone JF et al (1984) Inflammatory pancreatic masses. Problems in differentiating focal pancreatitis from carcinoma. Radiology 150:35–38

    CAS  PubMed  Google Scholar 

  • Niwa T, Ueno M et al (2009) Advanced pancreatic cancer: the use of the apparent diffusion coefficient to predict response to chemotherapy. Br J Radiol 82:28–34

    Article  CAS  PubMed  Google Scholar 

  • Oner AY, Celik H et al (2006) Single breath-hold diffusion-weighted MRI of the liver with parallel imaging: initial experience. Clin Radiol 61:959–965

    Article  CAS  PubMed  Google Scholar 

  • Parikh T, Drew SJ et al (2008) Focal liver lesion detection and characterization with diffusion-weighted MR imaging: comparison with standard breath-hold T2-weighted imaging. Radiology 246:812–822

    Article  PubMed  Google Scholar 

  • Shinya S, Sasaki T et al (2008) Usefulness of diffusion-weighted imaging (DWI) for the detection of pancreatic cancer: 4 case reports. Hepatogastroenterology 55:282–285

    PubMed  Google Scholar 

  • Shinya S, Sasaki T et al (2009) The efficacy of diffusion-weighted imaging for the detection of colorectal cancer. Hepatogastroenterology 56:128–132

    PubMed  Google Scholar 

  • Squillaci E, Manenti G et al (2004a) Correlation of diffusion-weighted MR imaging with cellularity of renal tumours. Anticancer Res 24:4175–4179

    PubMed  Google Scholar 

  • Squillaci E, Manenti G et al (2004b) Diffusion-weighted MR imaging in the evaluation of renal tumours. J Exp Clin Cancer Res 23:39–45

    CAS  PubMed  Google Scholar 

  • Sugahara T, Korogi Y et al (1999) Usefulness of diffusion-weighted MRI with echo-planar technique in the evaluation of cellularity in gliomas. J Magn Reson Imaging 9: 53–60

    Article  CAS  PubMed  Google Scholar 

  • Sun XJ, Quan XY et al (2005) Quantitative evaluation of diffusion-weighted magnetic resonance imaging of focal hepatic lesions. World J Gastroenterol 11:6535–6537

    PubMed  Google Scholar 

  • Takeuchi M, Matsuzaki K et al (2008) High-b-value diffusion-weighted magnetic resonance imaging of pancreatic cancer and mass-forming chronic pancreatitis: preliminary results. Acta Radiol 49:383–386

    Article  CAS  PubMed  Google Scholar 

  • Taouli B, Thakur RK et al (2009) Renal lesions: characterization with diffusion-weighted imaging versus contrast-enhanced MR imaging. Radiology 251:398–407

    Article  PubMed  Google Scholar 

  • Taouli B, Vilgrain V et al (2003) Evaluation of liver diffusion isotropy and characterization of focal hepatic lesions with two single-shot echo-planar MR imaging sequences: prospective study in 66 patients. Radiology 226:71–78

    Article  PubMed  Google Scholar 

  • Vossen JA, Buijs M et al (2008) Receiver operating characteristic analysis of diffusion-weighted magnetic resonance imaging in differentiating hepatic hemangioma from other hypervascular liver lesions. J Comput Assist Tomogr 32: 750–756

    Article  PubMed  Google Scholar 

  • Yamada I, Aung W et al (1999) Diffusion coefficients in abdominal organs and hepatic lesions: evaluation with intravoxel incoherent motion echo-planar MR imaging. Radiology 210: 617–623

    CAS  PubMed  Google Scholar 

  • Yamashita Y, Namimoto T et al (1998) Mucin-producing tumor of the pancreas: diagnostic value of diffusion-weighted echo-planar MR imaging. Radiology 208:605–609

    CAS  PubMed  Google Scholar 

  • Yamashita Y, Ogata I et al (1997) Cavernous hemangioma of the liver: pathologic correlation with dynamic CT findings. Radiology 203:121–125

    CAS  PubMed  Google Scholar 

  • Yoshikawa T, Kawamitsu H et al (2006) ADC measurement of abdominal organs and lesions using parallel imaging technique. AJR Am J Roentgenol 187:1521–1530

    Article  PubMed  Google Scholar 

  • Zhang J, Tehrani YM et al (2008) Renal masses: characterization with diffusion-weighted MR imaging–a preliminary experience. Radiology 247:458–464

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, Yamanashi University, Shimokato, Japan

    Ali Muhi & Tomoaki Ichikawa

Authors
  1. Ali Muhi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tomoaki Ichikawa
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Royal Marsden NHS Foundation Trust, Department of Radiology, Downs Road, Sutton, SM2 5PT, United Kingdom

    D. M. Koh

  2. Department of Diagnostic, Interventional and Paediatric Radiology, Universitätsspital Bern Inselspital, Freiburgstr. 10, Bern, 3010, Switzerland

    H. C. Thoeny

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Muhi, A., Ichikawa, T. (2010). DW-MRI for Disease Characterization in the Abdomen. In: Koh, D.M., Thoeny, H.C. (eds) Diffusion-Weighted MR Imaging. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-78576-7_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-78576-7_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-78575-0

  • Online ISBN: 978-3-540-78576-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation