Extramucosal Colon Biopsy

Abstract

Serial biopsies of the colon may be necessary in order to diagnose etiology of chronic constipation when rectal suction biopsy results are inconclusive. Laparoscopy provides an excellent minimal invasive option in obtaining multiple biopsies of the colon for histological evaluation. Laparoscopic extramucosal biopsies can be obtained using a simple 3 port technique and no prior bowel preparation is mandatory. When compared to full thickness biopsies, extramucosal colon biopsies offer the advantages of obtaining biopsy specimens without breaching the integrity of the colon mucosa. In case the mucosa is opened, simple intracorporeal suturing of the biopsy site can be performed laparoscopically. Laparoscopic extramucosal colon biopsies can be performed as a days care procedure and is associated with a low morbidity. The technique is well suited for the pediatric age group.