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Surgical Staging 2: Metastatic Disease

  • Chapter
Imaging of Bone Tumors and Tumor-Like Lesions

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Key Points

• Advances in the treatment of bone sarcomas have increased patient survival.

• Accurate staging of primary bone tumors influences treatment planning, determines patient prognosis, and improves patient outcomes.

• Bone sarcomas metastasize primarily to the lungs and other bones.

• Chest CT is the most sensitive modality for detecting pulmonary metastases.

• MRI of the entire bone containing the primary tumor is the most accurate modality for the detection of skip lesions.

• Tc-99m MDP skeletal scintigraphy is traditionally the modality employed for the detection of distant osseous metastases.

• Newer imaging techniques include FDG-PET and whole body MRI, which show promise for efficient and earlier detection of distant osseous and soft tissue metastases.

• Since FDG-PET and whole body MRI have different strengths and weaknesses, their roles in tumor staging may be complementary.

• Additional studies evaluating their performance on metastases from primary bone tumors, their effect on patient outcome, and their cost-effectiveness are needed.

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Authors and Affiliations

  1. Department of Radiology, Musculoskeletal Division, Massachusetts General Hospital, 55 Fruit Street, Yawkey 6E, 02114, Boston, MA, USA

    Ambrose J. Huang, Marc H. Willis, Susan V. Kattapuram & Miriam A. Bredella

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  1. Ambrose J. Huang
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  2. Marc H. Willis
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  3. Susan V. Kattapuram
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  4. Miriam A. Bredella
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Editor information

Editors and Affiliations

  1. MRI Department, Royal Orthopaedic Hospital, NHS Foundation Trust, Bristol Road South, Northfield, B31 2AP, Birmingham, UK

    A. Mark Davies

  2. Section of Musculoskeletal Radiology, Imaging Institute, Diagnostic Radiology/A21, School of Medicine of Case Western Reserve University, Cleveland Clinic Foundation, 9500 Euclid Ave., 44195, Cleveland, OH, USA

    Murali Sundaram

  3. Imaging Department, Royal Orthopaedic Hospital, NHS Foundation Trust, Bristol Road South, Northfield, B31 2AP, Birmingham, UK

    Steven L. J. James

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© 2009 Springer-Verlag Berlin Heidelberg

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Huang, A., Willis, M., Kattapuram, S., Bredella, M. (2009). Surgical Staging 2: Metastatic Disease. In: Davies, A., Sundaram, M., James, S. (eds) Imaging of Bone Tumors and Tumor-Like Lesions. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77984-1_10

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  • DOI: https://doi.org/10.1007/978-3-540-77984-1_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-77982-7

  • Online ISBN: 978-3-540-77984-1

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