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Treatment of Bone and Soft Tissue Sarcomas pp 25–36Cite as

Sentinel Node Biopsy in Soft Tissue Sarcome

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Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 179))

Abstract

While regional lymphatic spread develops in only 3%–4% of all patients with soft tissue sarcoma, there are several histological subtypes associated with a significantly higher propensity for regional lymph node metastasis. These include clear cell sarcoma, synovial sarcoma, rhabdomy-osarcoma, and epithelioid sarcoma. To date there is no validated, noninvasive method to assess regional lymph node status. A potentially useful diagnostic tool is lymphatic mapping with sentinel lymph node biopsy, a concept that has revolutionized the treatment of patients with intermediate thickness melanoma and early stage breast cancer. The purpose of this study is to provide an overview of the procedure of sentinel lymph node biopsy and the data available on its application in patients with soft tissue sarcomas.

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Authors and Affiliations

  1. Department of Orthopedic Oncology Sarkomzentrum Berlin-Brandenburg, Helios Klinikum Berlin-Buch, Schwanebecker Chaussee 50, Berlin, 13125, Germany

    Dimosthenis Andreou MD

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  1. Dimosthenis Andreou MD
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  2. Per-Ulf Tunn MD
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  1. Leiter Department Tumororthopädie Klinik für Orthopädie und Orthopädische Rheumatologie, HELIOS-Klinikum Berlin, Schwanebecker Chaussee 50, Berlin, 13125

    Per-Ulf Tunn

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Andreou, D., Tunn, PU. (2009). Sentinel Node Biopsy in Soft Tissue Sarcome. In: Tunn, PU. (eds) Treatment of Bone and Soft Tissue Sarcomas. Recent Results in Cancer Research, vol 179. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77960-5_3

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  • DOI: https://doi.org/10.1007/978-3-540-77960-5_3

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