Comparative Studies of Intracranial Pressure in Patients With and Without Space-Occupying Lesions

  • Lisbeth Krogh
  • Georg E. Cold


Anaesthesia for craniotomy has to be carried out with emphasis on haemodynamic stability, a sufficient cerebral perfusion pressure and avoidance of agents or procedures that increase ICP. The patients presented to a current neuroanaesthesiological practice come with a multitude of intracranial pathologies, ranging from discrete unruptured aneurisms to significantly sized tumours that create a midline shift. It is important to relate the ICP measured in patients with space-occupying lesions to the ICP in patients without lesions. Studies of ICP during craniotomy in patients without space-occupying intracerebral lesions, however, are few. In this chapter data on two populations, one with supratentorial glioblastomas and the other without space-occupying lesions, are presented. Differences between the groups, in ICP and other relevant data obtained, are discussed and the relationship between neuroradiological data and measured ICP correlated.


Intracranial Pressure Cerebral Perfusion Pressure Cerebral Autoregulation Midline Shift Unruptured Cerebral Aneurysm 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Lisbeth Krogh
    • 1
  • Georg E. Cold
    • 2
  1. 1.Department of NeuroanaesthesiaAarhus University HospitalAarhus CDenmark
  2. 2.Aarhus VDenmark

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