Effect of Hyperventilation on Subdural Intracranial Pressure

  • Lise Schlünzen
  • Georg E. Cold


Hyperventilation has been used in the treatment of patients with intracranial pathologies for decades. In the neurointensive care unit the use of hyperventilation is on retreat due to the risk of cerebral ischaemia. During surgery the situation is somewhat different because of the shorter duration of hyperventilation and the close monitoring of physiological parameters. In this chapter the results of three studies regarding the effect of hyperventilation on subdural ICP and cerebral haemodynamics during four anaesthetic regimes are presented. The inhalation agents most often used in western countries, isoflurane and sevoflurane, as well as the total intravenous anaesthetic regimes of propofol-fentanyl and propofol-remifentanil, and the influence on ICP during hyperventilation are discussed.


Cerebral Autoregulation Cerebral Blood Flow Velocity Cerebral Tumour Anaesthetic Regime Mannitol Treatment 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Lise Schlünzen
    • 1
  • Georg E. Cold
    • 2
  1. 1.Department of NeuroanaesthesiaAarhus University HospitalAarhus CDenmark
  2. 2.Aarhus VDenmark

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