Abstract
In the 19 years since the first CB transplantation was reported in the New England Journal of Medicine [9], the fields of CB research, banking and transplantation have flourished [2]. Umbilical CB has made allogeneic hematopoietic stem cell transplantation available to patients who do not have an HLA-identical sibling or an unrelated donor [20]. CB transplantation has been used to successfully treat leukemia, lymphoma, myelodysplasia, aplastic anemia, hemoglobinopathies, metabolic storage diseases, and immunodeficiencies. There are more than 300,000 unrelated CB units stored in 40 banks, and more than 10,000 CB transplants have been performed [20].
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Kögler, G. (2009). The Unrestricted Somatic Stem Cell (USSC) From Cord Blood For Regenerative Medicine. In: Meyer, U., Handschel, J., Wiesmann, H., Meyer, T. (eds) Fundamentals of Tissue Engineering and Regenerative Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77755-7_14
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