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Clinical Presentation

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Primary Optic Nerve Sheath Meningioma

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

ONSM typically affects middle aged women. Ophthalmologic presentation in the vast majority of patients consists in the classical features of optic neuropathy. The vast majority of patients exhibit a variable loss of vision and/or visual field, almost always accompanied by funduscopic evidence of optic nerve pathology. Optic nerve involvement presents in one half of those affected either as a disc swelling or optic atrophy. Careful examination will virtually always reveal a reduced amplitude and velocity of pupillary light reaction, a so-called relative afferent pupillary defect. Proptosis and motility impairment may develop; however they usually are only of moderate degree. Disease progression is slow, but in many cases results in blindness if left untreated. While in the adult patient population, prognosis quo ad vitam is excellent, childhood ONSM runs a more aggressive course and may be a sign of neurofibromatosis.

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Author information

Authors and Affiliations

  1. University Eye Hospital, Langenbeckstrasse 1, 55101, Mainz, Germany

    Susanne Pitz

  2. University Eye Hospital, Schleichstrasse 12–16, 72016, Tübingen, Germany

    Helmut Wilhelm

Authors
  1. Susanne Pitz
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  2. Helmut Wilhelm
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Editor information

Editors and Affiliations

  1. International Atomic Energy Agency, Wagramer Strasse 5, P.O. Box 100, 1400, Vienna, Austria

    Branislav Jeremic

  2. University Eye Hospital, Langenbeckstrasse 1, 55101, Mainz, Germany

    Susanne Pitz

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© 2008 Springer-Verlag Berlin Heidelberg

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Pitz, S., Wilhelm, H. (2008). Clinical Presentation. In: Jeremic, B., Pitz, S. (eds) Primary Optic Nerve Sheath Meningioma. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77558-4_2

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  • DOI: https://doi.org/10.1007/978-3-540-77558-4_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-77557-7

  • Online ISBN: 978-3-540-77558-4

  • eBook Packages: MedicineMedicine (R0)

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