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Hypercapnia: Permissive, Therapeutic, or Not at All?

  • Conference paper
Yearbook of Intensive Care and Emergency Medicine

Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 2008))

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Abstract

In the past, hypercapnia and its concomitant hypercapnic acidosis, have been considered to be adverse, and were strictly avoided in the critically ill. Support for this approach derived from concerns regarding the link between hypercapnia and/or acidosis and adverse outcome in diverse clinical contexts, including cardiac arrest, sepsis, and neonatal asphyxia [1]. However, accumulating evidence from experimental and clinical studies demonstrates the potential for mechanical ventilation to directly injure the lungs — a phenomenon termed ‘ventilator-induced lung injury (VILI)’ — and has mandated a rethink of our approaches to hypercapnia.

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Authors and Affiliations

  1. Department of Anesthesia, Clinical Sciences Institute, National University of Ireland, Galway, Ireland

    P. Hassett, M. Contreras & J. G. Laffey

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  1. P. Hassett
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  2. M. Contreras
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  3. J. G. Laffey
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Hassett, P., Contreras, M., Laffey, J.G. (2008). Hypercapnia: Permissive, Therapeutic, or Not at All?. In: Yearbook of Intensive Care and Emergency Medicine. Yearbook of Intensive Care and Emergency Medicine, vol 2008. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77290-3_25

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  • DOI: https://doi.org/10.1007/978-3-540-77290-3_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-77289-7

  • Online ISBN: 978-3-540-77290-3

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