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Hepatology Textbook and Atlas pp 737–772Cite as

Liver cirrhosis

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Abstract

Aretaeus (2nd century AD) coined the term “skirros”, because he thought that inflammation of the liver led to its hardening (=skirros). • In 1543 A. Vesal described the granulation of the liver surface as being responsible for the compression of the small hepatic vessels. Even at that time, he associated these changes, which were thought to accompany a shrinking of the liver, with alcohol consumption. • When J. Posthius (1590) described ascites, he said that the changed liver was “all granulated inside”. A drawing by J. Brown (1685) shows coarse nodular liver cirrhosis. G. B. Morgagni (1761) also wrote a treatise on cirrhosis, in which he described the small vessels as being compressed due to a shrinking and hardened liver. M. Baillie (1818) wrote an excellent description of the morphology of liver cirrhosis and, like A. Vesal, also postulated a causal connection with excessive alcohol consumption. The first accurate report on atrophic, portal cirrhosis was given by R.T.H. Laennec (1819) an incidental inclusion in his book “Traité ďauscultation”.

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© 2008 Springer Medizin Verlag Heidelberg

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(2008). Liver cirrhosis. In: Hepatology Textbook and Atlas. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-76839-5_35

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  • DOI: https://doi.org/10.1007/978-3-540-76839-5_35

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