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Organic Semiconductors in Sensor Applications pp 39–60Cite as

Polyelectrolyte-Based Fluorescent Sensors

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Part of the book series: Materials Science ((SSMATERIALS,volume 107))

Chemo- and biosensors based on fluorescent polyelectrolytes are discussed. The amplified quenching of conjugated polyelectrolytes by oppositely charged quenchers can be used in bioassays to monitor activities of protease, phospholipase A2, and phospholipase C by varying substrates. Enhanced fluorescence yields from cyanine dye J aggregates formed by supramolecular self-assembly between the dyes and polysaccharides can be utilized in assays to monitor glycosidase activity. In addition solution based polyelectrolyte sensors, amplified quenching properties of surface grafted conjugated polyelectrolytes by energy transfer and electron transfer type quenchers are compared.

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References

  1. L.H. Chen, D.W. McBranch, H.L. Wang, R. Helgeson, F. Wudl, D.G. Whitten, Proc. Natl. Acad. Sci. USA 96(22), 12287 (1999)

    Article  ADS  Google Scholar 

  2. J.C. Russell, D.G. Whitten, A.M. Braun, J. Am. Chem. Soc. 103(11), 3219 (1981)

    Article  Google Scholar 

  3. R.M. Jones, T.S. Bergstedt, D.W. McBranch, D.G. Whitten, J. Am. Chem. Soc. 123(27), 6726 (2001)

    Article  Google Scholar 

  4. R.M. Jones, T.S. Bergstedt, C.T. Buscher, D. McBranch, D. Whitten, Langmuir 17(9), 2568 (2001)

    Article  Google Scholar 

  5. L.D. Lu, R. Helgeson, R.M. Jones, D. McBranch, D. Whitten, J. Am. Chem. Soc. 124(3), 483 (2002)

    Article  Google Scholar 

  6. R.M. Jones, L.D. Lu, R. Helgeson, T.S. Bergstedt, D.W. McBranch, D.G. Whitten, Proc. Natl. Acad. Sci. USA 98(26), 14769 (2001)

    Article  ADS  Google Scholar 

  7. L.D. Lu, R.M. Jones, D. McBranch, D. Whitten, Langmuir 18(20), 7706 (2002)

    Article  Google Scholar 

  8. D.G. Whitten, K.E. Achyuthan, G.P. Lopez, O.K. Kim, Pure Appl. Chem. 78(12), 2313 (2006)

    Article  Google Scholar 

  9. M.R. Pinto, C. Tan, M.B. Ramey, J.R.Pinto, T.S. Bergstedt, D.G. Whitten, K.S. Schanze, Res. Chem. Intermed. 33(1, 2), 79 (2007)

    Article  Google Scholar 

  10. B.S. Harrison, M.B. Ramey, J.R. Reynolds, K.S. Schanze, J. Am. Chem. Soc. 122(35), 8561 (2000)

    Article  Google Scholar 

  11. M.R. Pinto, K.S. Schanze, Proc. Natl. Acad. Sci. USA. 101(20), 7505 (2004)

    Article  ADS  Google Scholar 

  12. K.E. Achyuthan, T.S. Bergstedt, L. Chen, R.M. Jones, S. Kumaraswamy, S.A. Kushon, K.D. Ley, L. Lu, D. McBranch, H. Mukundan, F. Rininsland, X. Shi, W. Xia, D.G. Whitten, J. Mater. Chem. 15(27, 28), 2648 (2005)

    Article  Google Scholar 

  13. S.A. Kushon, K.D. Ley, K. Bradford, R.M. Jones, D. McBranch, D. Whitten, Langmuir 18(20), 7245 (2002)

    Article  Google Scholar 

  14. S.A. Kushon, K. Bradford, V. Marin, C. Suhrada, B.A. Armitage, D. McBranch, D. Whitten, Langmuir 19(16), 6456 (2003)

    Article  Google Scholar 

  15. S. Kumaraswamy, T. Bergstedt, X.B. Shi, F. Rininsland, S. Kushon, W.S. Xia, K. Ley, K. Achyuthan, D. McBranch, D. Whitten, Proc. Natl. Acad. Sci. USA 101(20), 7511 (2004)

    Article  ADS  Google Scholar 

  16. F. Rininsland, W.S. Xia, S. Wittenburg, X.B. Shi, C. Stankewicz, K. Achyuthan, D. McBranch, D. Whitten, Proc. Natl. Acad. Sci. USA 101(43), 15295 (2004)

    Article  ADS  Google Scholar 

  17. R. Zeineldin, M.E. Piyasena, T.S. Bergstedt, L.A. Sklar, D. Whitten, G.P. Lopez, Cytom Part A, 69A(5), 335 (2006)

    Article  Google Scholar 

  18. O.K. Kim, J. Je, G. Jernigan, L. Buckley, D. Whitten, J. Am. Chem. Soc. 128(2), 510 (2006)

    Article  Google Scholar 

  19. K.E. Achyuthan, L.D. Lu, G.P. Lopez, D.G. Whitten, Photochem. Photobiol. Sci. 5(10), 931 (2006)

    Article  Google Scholar 

  20. J.A. Nicholson, T.J. Peters, Anal. Biochem. 87(2), 418 (1978)

    Article  Google Scholar 

  21. D.H. Porter, H.E. Swaisgood, G.L. Catignani, Anal. Biochem. 123(1), 41 (1982)

    Article  Google Scholar 

  22. J. Dalvi-Malhotra, L.H. Chen, J. Phys. Chem. B 109(9), 3873 (2005)

    Article  Google Scholar 

  23. L.H. Chen, D. McBranch, R. Wang, D. Whitten, Chem. Phys. Lett. 330(1, 2), 27 (2000)

    Article  ADS  Google Scholar 

  24. L.H. Chen, S. Xu, D. McBranch, D. Whitten, J. Am. Chem. Soc. 122(38), 9302 (2000)

    Article  Google Scholar 

  25. J.H. Exton, J. Biol. Chem. 265(1), 1 (1990)

    Google Scholar 

  26. J.J. Schrijen, A. Omachi, W.A.H.M. Vangroningenluyben, J.J.H.H.M. Depont, S.L. Bonting, Biochim. Biophys. Acta 649(1), 1 (1981)

    Article  Google Scholar 

  27. T. Takahashi, T. Sugahara, A. Ohsaka, Methods Enzymol. 71 (Lipids, Pt. C), 710 (1981)

    Article  Google Scholar 

  28. S. Zhang, Y. Xu, B. Wang, W. Qiao, D. Liu, Z. Li, J. Contr. Release 100(2), 165 (2004)

    Article  Google Scholar 

  29. R.I. Zhdanov, O.V. Podobed, V.V. Vlassov, Bioelectrochemistry 58(1), 53 (2002)

    Article  Google Scholar 

  30. K. Kugiyama, Y. Ota, K. Takazoe, Y. Moriyama, H. Kawano, Y. Miyao, T. Sakamoto, H. Soejima, H. Ogawa, H. Doi, S. Sugiyama, H. Yasue, Circulation 100(12), 1280 (1999)

    Google Scholar 

  31. M. Rigoni, G. Schiavo, A.E. Weston, P. Caccin, F. Allegrini, M. Pennuto, F. Valtorta, C. Montecucco, O. Rossetto, J. Cell Sci. 117(16), 3561 (2004)

    Article  Google Scholar 

  32. T.M. Rose, G.D. Prestwich, Acs Chem. Biol. 1(2), 83 (2006)

    Article  Google Scholar 

  33. J.U. Eskola, T.J. Nevalainen, T.N.E. Lovgren, Clin. Chem. 29(10), 1777 (1983)

    Google Scholar 

  34. M. Jimenez, J. Cabanes, F. Gandia-Herrero, J. Escribano, F. Garcia-Carmona, M. Perez-Gilabert, Anal. Biochem. 319(1), 131 (2003)

    Article  Google Scholar 

  35. M. Bednarz, J. Knoester, J. Phys. Chem. B 105(51), 12913 (2001)

    Article  Google Scholar 

  36. C. Spitz, J. Knoester, A. Ouart, S. Daehne, Chem. Phys. 275(1–3), 271 (2002)

    Article  Google Scholar 

  37. J. Moll, W.J. Harrison, D.V. Brumbaugh, A.A. Muenter, J. Phys. Chem. A, 104(39), 8847 (2000)

    Article  Google Scholar 

  38. G.D. Scholes, Annu. Rev. Phys. Chem. 54(57), (2003)

    Article  ADS  Google Scholar 

  39. T. Kobayashi (ed.), J-Aggregates (World Scientific, Singapore, 1996)

    Google Scholar 

  40. X.D. Song, C. Geiger, M. Farahat, J. Perlstein, D.G. Whitten, J. Am. Chem. Soc. 119(51), 12481 (1997)

    Article  Google Scholar 

  41. D.G. Whitten, L.H. Chen, H.C. Geiger, J. Perlstein, X.D. Song, J. Phys. Chem. B 102(50), 10098 (1998)

    Article  Google Scholar 

  42. M. Reers, T.W. Smith, L.B. Chen, Biochemistry 30(18), 4480 (1991)

    Article  Google Scholar 

  43. C. McCullough, M. Heywood, H. Samha, Am. J. Undergrad. Res. 4(3), 1 (2005)

    Google Scholar 

  44. N. Kato, J. Prime, K. Katagiri, F. Caruso, Langmuir 20(14), 5718 (2004)

    Article  Google Scholar 

  45. I. Place, J. Perlstein, T.L. Penner, D.G. Whitten, Langmuir 16(23), 9042 (2000)

    Article  Google Scholar 

  46. A. Mishra, R.K. Behera, P.K. Behera, B.K. Mishra, G.B. Behera, Chem. Rev. 100(6), 1973 (2000)

    Article  Google Scholar 

  47. R. Stern, M.J. Jedrzejas, Chem. Rev. 106(3), 818 (2006)

    Article  Google Scholar 

  48. K. Sakurai, S. Shinkai, J. Inclusion Phenom. Macrocyclic Chem. 41(1–4), 173 (2001)

    Article  Google Scholar 

  49. T. Sagawa, H. Tobata, H. Ihara, Chem. Commun. 39(18), 2090 (2004)

    Article  Google Scholar 

  50. M.M. Wang, G.L. Silva, B.A. Armitage, J. Am. Chem. Soc. 122(41), 9977 (2000)

    Article  Google Scholar 

  51. K.M. Sovenyhazy, J.A. Bordelon, J.T. Petty, Nucleic Acids Res. 31(10), 2561 (2003)

    Article  Google Scholar 

  52. K.L. Vedvik, H.C. Eliason, R.L. Hoffman, J.R. Gibson, K.R. Kupcho, R.L. Somberg, K.W. Vogel, Assay Drug Dev. Technol. 2(2), 193 (2004)

    Article  Google Scholar 

  53. D.M. Olive, Expert Rev. Proteomics 1(3), 327 (2004)

    Article  MathSciNet  Google Scholar 

  54. J.J. Davis, Chem. Commun. 40(28), 3509 (2005)

    Article  Google Scholar 

  55. K. Ogawa, S. Chemburu, G.P. Lopez, D.G. Whitten, K.S. Schanze, Langmuir 23(8), 4541 (2007)

    Article  Google Scholar 

  56. M. Beinhoff, A.T. Appapillai, L.D. Underwood, J.E. Frommer, K.R. Carter, Langmuir 22(6), 2411 (2006)

    Article  Google Scholar 

  57. S.S. Lehrer, Biochemistry 10(17), 3254 (1971)

    Article  Google Scholar 

  58. Y.K. Gong, T. Miyamoto, K. Nakashima, S. Hashimoto, J. Phys. Chem. B, 104(24), 5772 (2000)

    Article  Google Scholar 

  59. J.R. Lakowicz, Principles of Fluorescent Spectroscopy, 2nd edn. (Plenum Publishers, New York, 1999)

    Google Scholar 

  60. Y. Liu, K. Ogawa, K.S. Schanze, Anal. Chem. Web ASAP, (2007), DOI: 10.1021/ac 701672a.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Chemistry, University of Florida, 32611, Gainesville, FL, USA

    K. Ogawa, E. Ji, Y. Liu & S. Schanze

  2. Department of Biosensors and Nanomaterials, Sandia National Laboratories, 87123, Albuquerque, NM, USA

    K. E. Achyuthan

  3. Center for Biomedical Engineering, University of New Mexico, 87131, Albuquerque, NM, USA

    S. Chemburu, G. P. Lopez & D. G. Whitten

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  1. K. Ogawa
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  2. K. E. Achyuthan
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Editor information

Editors and Affiliations

  1. Department of Materials Science and Engineering, Cornell University, 327 Bard Hall, 14853, Ithaca, NY, USA

    Daniel A. Bernards  & George G. Malliaras  & 

  2. Department of Biomedical Engineering, Cornell University, Hungerford Hill Road, 14853, Ithaca, NY, USA

    Róisín M. Owens

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Ogawa, K. et al. (2008). Polyelectrolyte-Based Fluorescent Sensors. In: Bernards, D.A., Malliaras, G.G., Owens, R.M. (eds) Organic Semiconductors in Sensor Applications. Materials Science, vol 107. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-76314-7_2

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