Abstract
Recent changes in data management within post-genomic clinical trials have emphasized the need for novel methods and tools to solve semantic and syntactic heterogeneities among distributed sources of information. ACGT is an Integrated Project funded by the European Commission that aims at building a GRID-based platform comprised by a set of tools to support multi-centric post-genomic clinical trials on cancer. The main goal of ACGT is to provide seamless access to heterogeneous sources of information. For this purpose, two core tools were developed and included in the ACGT architecture: the ACGT Semantic Mediator (ACGT-SM), and the Data Access Wrappers (ACGT-DAWs). The ACGT-SM addresses semantics and schema integration, while the ACGT-DAWs cope with syntactic heterogeneities. Once the sources are bridged together, they can be seamlessly accessed using the RDQL query language.We tested our tools using a set of three relational and DICOM based image sources obtaining promising results.
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References
Kimball, R.: The Data Warehouse Toolkit: Practical Techniques for Building Dimensional Data Warehouses. John Wiley, New York (1996)
Sheth, A.P., Larson, J.A.: Federated Database Systems for Managing Distributed, Heterogeneous, and Autonomous Databases. ACM Computing Surveys 22(3), 183–236 (1990)
Wiederhold, G.: Mediators in the Architecture of Future Information Systems. IEEE Computer 25(3), 38–49 (1992)
Cali, A., De Giacomo, G., Lenzerini, M.: Models for information integration: Turning local-as-view into global-as-view. In: Proc. of Int. Workshop on Foundations of Models for Information Integration (10th Workshop in the series Foundations of Models and Languages for Data and Objects) (2001)
Abiteboul, S., Duschka, O.: Complexity of answering queries using materialized views. In: PODS 1998. Proc. of the 17th ACM SIGACT SIGMOD SIGART Symp. on Principles of Database Systems, pp. 254–265. ACM Press, New York (1998)
Ullman, J.D.: Information integration using logical views. In: Afrati, F.N., Kolaitis, P.G. (eds.) ICDT 1997. LNCS, vol. 1186, pp. 19–40. Springer, Heidelberg (1996)
National Electrical Manufacturers Association: Digital Imaging and Communications in Medicine (DICOM) (2004) (last accessed in May 2007), http://medical.nema.org/dicom/2004.html
http://www.w3.org/Submission/RDQL/ (last accessed in May 2007)
http://www.w3.org/2004/OWL/ (last accessed in May 2007)
Prud’hommeaux, E., Seaborne A.: SPARQL Query Language for RDF, W3C Working Draft (March 26, 2007) (last accessed in May 2007), http://www.w3.org/TR/2007/WD-rdf-sparql-query-20070326/
http://www.w3.org/TR/rdf-sparql-XMLres/ (last accessed in May 2007)
http://www.cs.waikato.ac.nz/ml/weka/ (last accessed in May 2007)
Antonioletti, M., et al.: The Design and Implementation of Grid Database Services in OGSA-DAI. Concurrency and Computation: Practice and Experience 17(2-4), 357–376 (2005)
Eisenberg, A., Melton, J., Kulkarni, K., Michels, J., Zemke, F.: SQL:2003 has been published. SIGMOD Rec. 33(1), 119–126 (2004)
Bizer, C., Seaborne, A.: D2RQ - Treating Non-RDF Databases as Virtual RDF Graphs. In: McIlraith, S.A., Plexousakis, D., van Harmelen, F. (eds.) ISWC 2004. LNCS, vol. 3298, Springer, Heidelberg (2004)
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Martín, L. et al. (2007). Data Access and Management in ACGT: Tools to Solve Syntactic and Semantic Heterogeneities Between Clinical and Image Databases. In: Hainaut, JL., et al. Advances in Conceptual Modeling – Foundations and Applications. ER 2007. Lecture Notes in Computer Science, vol 4802. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-76292-8_4
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DOI: https://doi.org/10.1007/978-3-540-76292-8_4
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