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Thyroid

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Abbreviations

CCSS:

Childhood cancer survivor study

PTU:

Propylthiouracil

RiSK:

Registry for the evaluation of side effects after radiotherapy in childhood and adolescence

SEER:

Surveillance epidemiology end results

TRH:

Thyrotropin-releasing hormone

TSH:

Thyroid-stimulating hormone

References

  • Acharya S, Sarafoglou K, LaQuaglia M et al (2003) Thyroid neoplasms after therapeutic radiation for malignancies during childhood or adolescence. Cancer 97:2397–2403

    Article  PubMed  Google Scholar 

  • Adams MJ, Shore RE, Dozier A et al (2010) Thyroid cancer risk 40 + years after irradiation for an enlarged thymus: an update of the Hempelmann cohort. Radiat Res 174:753–762

    Article  PubMed  CAS  Google Scholar 

  • Alterio D, Jereczek-Fossa BA, Franchi B et al (2007) Thyroid disorders in patients treated with radiotherapy for head-and-neck cancer: a retrospective analysis of seventy-three patients. Int J Radiat Oncol Biol Phys 67:144–150

    Article  PubMed  Google Scholar 

  • American Association of Clinical Endocrinologists and Associazione (2006) Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules. Endocr Pract 12:63–102

    Google Scholar 

  • Bakhshandeh M, Hashemi B, Mahdavi SR et al (2012) Normal tissue complication probability modeling of radiation-induced hypothyroidism after head-and-neck radiation therapy. Int J Radiat Oncol Biol Phys (In press)

    Google Scholar 

  • Bakker B, Massa GG, van Rijn AM et al (1999) Effects of total-body irradiation on growth, thyroid and pituitary gland in rhesus monkeys. Radiother Oncol 51:187–192

    Article  PubMed  CAS  Google Scholar 

  • Beahrs OH (1976) Workshop on late effects of irradiation to the head and neck in infancy and childhood. Radiology 120:733–734

    PubMed  CAS  Google Scholar 

  • Becker FO, Economou SG, Southwick HW et al (1975) Adult thyroid cancer after head and neck irradiation in infancy and childhood. Ann Intern Med 83:347–351

    Article  PubMed  CAS  Google Scholar 

  • Berger C, Le-Gallo B, Donadieu J et al (2005) Late thyroid toxicity in 153 long-term survivors of allogeneic bone marrow transplantation for acute lymphoblastic leukaemia. Bone Marrow Transplant 35:991–995

    Article  PubMed  CAS  Google Scholar 

  • Bethge W, Guggenberger D, Bamberg M et al (2000) Thyroid toxicity of treatment for Hodgkin’s disease. Ann Hematol 79:114–118

    Article  PubMed  CAS  Google Scholar 

  • Bhandare N, Kennedy L, Malyapa RS et al (2007) Primary and central hypothyroidism after radiotherapy for head-and-neck tumors. Int J Radiat Oncol Biol Phys 68:1131–1139

    Article  PubMed  Google Scholar 

  • Bhatia S, Yasui Y, Robison LL et al (2003) High risk of subsequent neoplasms continues with extended follow-up of childhood Hodgkin’s disease: report from the Late Effects Study Group. J Clin Oncol 21:4386–4394

    Article  PubMed  Google Scholar 

  • Bhatti P, Veiga LH, Ronckers CM et al (2010) Risk of second primary thyroid cancer after radiotherapy for a childhood cancer in a large cohort study: an update from the childhood cancer survivor study. Radiat Res 174:741–752

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Blitzer JB, Paolozzi FP, Gottlieb AJ et al (1985) Thyrotoxic thyroiditis after radiotherapy for Hodgkin’s disease. Arch Intern Med 145:1734–1735

    Article  PubMed  CAS  Google Scholar 

  • Bolling T, Geisenheiser A, Pape H et al (2010) Hypothyroidism after head-and-neck radiotherapy in children and adolescents: Preliminary results of the registry for the evaluation of side effects after radiotherapy in childhood and adolescence (RiSK). Int J Radiat Oncol Biol Phys

    Google Scholar 

  • Boomsma MJ, Bijl HP, Christianen ME et al (2012) A prospective cohort study on radiation-induced hypothyroidism: development of an NTCP model. Int J Radiat Oncol Biol Phys (In press)

    Google Scholar 

  • Boomsma MJ, Bijl HP, Langendijk JA (2011) Radiation-induced hypothyroidism in head and neck cancer patients: a systematic review. Radiother Oncol 99:1–5

    Article  PubMed  CAS  Google Scholar 

  • Bower J, Clark J (1923) Resistance of thyroid gland to action of radium x-rays: result of experimental implntation of radium needles in thyroid of dogs. Am J Roentgenol Rad Ther 10:632–643

    Google Scholar 

  • Bryer-Ash M, Lodhi W, Robbins K et al (2001) Early thyrotoxic thyroiditis after radiotherapy for tonsillar carcinoma. Arch Otolaryngol Head Neck Surg 127:209–211

    Article  PubMed  CAS  Google Scholar 

  • Carr RF, LiVolsi VA (1989) Morphologic changes in the thyroid after irradiation for Hodgkin’s and non-Hodgkin’s lymphoma. Cancer 64:825–829

    Article  PubMed  CAS  Google Scholar 

  • Cella L, Conson M, Caterino M et al (2011) Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin’s lymphoma. Int J Radiat Oncol Biol Phys

    Google Scholar 

  • Chow EJ, Friedman DL, Stovall M et al (2009) Risk of thyroid dysfunction and subsequent thyroid cancer among survivors of acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer 53:432–437

    Article  PubMed  PubMed Central  Google Scholar 

  • Colevas AD, Read R, Thornhill J et al (2001) Hypothyroidism incidence after multimodality treatment for stage III and IV squamous cell carcinomas of the head and neck. Int J Radiat Oncol Biol Phys 51:599–604

    Article  PubMed  CAS  Google Scholar 

  • Common Late Effects of Childhood Cancer by Body System: Thyroid Gland (2008). Available. http://www.cancer.gov/cancertopics/pdq/treatment/lateeffects/HealthProfessional/page3#Section_67. Accessed 30 June 2008

  • Constine LS, Donaldson SS, McDougall IR et al (1984) Thyroid dysfunction after radiotherapy in children with Hodgkin’s disease. Cancer 53:878–883

    Article  PubMed  CAS  Google Scholar 

  • Constine LS, Woolf PD, Cann D et al (1993) Hypothalamic-pituitary dysfunction after radiation for brain tumors. N Engl J Med 328:87–94

    Article  PubMed  CAS  Google Scholar 

  • Constine LS, Tarbell N, Hudson MM et al (2008) Subsequent malignancies in children treated for Hodgkin’s disease: association with gender and radiation dose. Int J Radiat Oncol Biol Phys 72:24–33

    Article  PubMed  PubMed Central  Google Scholar 

  • Cooper DS, Doherty GM, Haugen BR et al (2006) Management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 16:109–142

    Article  PubMed  Google Scholar 

  • Daniell HW (2002) Hypothyroidism: a frequent event after radiotherapy for patients with head and neck carcinoma. Cancer 95:673–4. Author reply 674

    Google Scholar 

  • Diaz R, Jaboin JJ, Morales-Paliza M et al (2010) Hypothyroidism as a consequence of intensity-modulated radiotherapy with concurrent taxane-based chemotherapy for locally advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 77:468–476

    Article  PubMed  Google Scholar 

  • Eckert C, Probstein J, Galison S (1937) Radiation of the thyroid. Radiology 29:40–44

    Google Scholar 

  • Einhorn J, Wilkholm G (1967) Hypothyroidism after external irradiation to the thyroid region. Radiology 88:326–328

    PubMed  CAS  Google Scholar 

  • Einhorn J, Fagraeus A, Jonsson J (1965) Thyroid antibodies after 131-I treatment for hyperthyroidism. J Clin Endocrinol Metab 25:1218–1224

    Article  PubMed  CAS  Google Scholar 

  • Fachnie JD, Rao SD (1980) Painless thyroiditis with hyperthyroidism following external irradiation to the neck. Henry Ford Hosp Med J 28:149–151

    PubMed  CAS  Google Scholar 

  • Fajardo L, Berthrong M, Anderson R (2001) Radiation pathology. Oxford University Press, New York, pp 337–343

    Google Scholar 

  • Faraci M, Barra S, Cohen A et al (2005) Very late nonfatal consequences of fractionated TBI in children undergoing bone marrow transplant. Int J Radiat Oncol Biol Phys 63:1568–1575

    Article  PubMed  Google Scholar 

  • Favus MJ, Schneider AB, Stachura ME et al (1056) Thyroid cancer occurring as a late consequence of head-and-neck irradiation. Evaluation of patients. N Engl J Med 294(1019–25):1976

    Google Scholar 

  • Felix H, Dupre N, Drape M et al (1961) Long-term influence of radiotherapy for cancer of larynx on the appearance of myxedema. Lyon Med 93:1043–1050

    PubMed  CAS  Google Scholar 

  • Freedberg AS, Kurland GS, Blumgart HL (1952) The pathologic effects of I131 on the normal thyroid gland of man. J Clin Endocrinol Metab 12:1315–1348

    Article  PubMed  CAS  Google Scholar 

  • Garcia-Serra A, Amdur RJ, Morris CG et al (2005) Thyroid function should be monitored following radiotherapy to the low neck. Am J Clin Oncol 28:255–258

    Article  PubMed  Google Scholar 

  • Garwicz S, Anderson H, Olsen JH et al (2000) Second malignant neoplasms after cancer in childhood and adolescence: a population-based case-control study in the 5 Nordic countries. The nordic society for pediatric hematology and oncology. The association of the nordic cancer Registries. Int J Cancer 88:672–678

    Article  PubMed  CAS  Google Scholar 

  • Glatstein E, McHardy-Young S, Brast N et al (1971) Alterations in serum thyrotropin (TSH) and thyroid function following radiotherapy in patients with malignant lymphoma. J Clin Endocrinol Metab 32:833–841

    Article  PubMed  CAS  Google Scholar 

  • Groover T, Christie A, Merritt E et al (1929) Roentgen radiation in the treatment of hyperthyroidism: a statistical evaluation based on 305 cases. JAMA 92:1730–1734

    Article  Google Scholar 

  • Hancock SL, Cox RS, McDougall IR (1991) Thyroid diseases after treatment of Hodgkin’s disease. N Engl J Med 325:599–605

    Article  PubMed  CAS  Google Scholar 

  • Hancock SL, McDougall IR, Constine LS (1995) Thyroid abnormalities after therapeutic external radiation. Int J Radiat Oncol Biol Phys 31:1165–1170

    Article  PubMed  CAS  Google Scholar 

  • Huang J, Walker R, Groome PG et al (2001) Risk of thyroid carcinoma in a female population after radiotherapy for breast carcinoma. Cancer 92:1411–1418

    Article  PubMed  CAS  Google Scholar 

  • Illes A, Biro E, Miltenyi Z et al (2003) Hypothyroidism and thyroiditis after therapy for Hodgkin’s disease. Acta Haematol 109:11–17

    Article  PubMed  Google Scholar 

  • Jereczek-Fossa BA, Alterio D, Jassem J et al (2004) Radiotherapy-induced thyroid disorders. Cancer Treat Rev 30:369–384

    Article  PubMed  CAS  Google Scholar 

  • Kaplan MM, Garnick MB, Gelber R et al (1983) Risk factors for thyroid abnormalities after neck irradiation for childhood cancer. Am J Med 74:272–280

    Article  PubMed  CAS  Google Scholar 

  • Karmisholt J, Andersen S, Laurberg P (2008) Variation in thyroid function tests in patients with stable untreated subclinical hypothyroidism. Thyroid 18:303–308

    Article  PubMed  Google Scholar 

  • Karmisholt J, Andersen S, Laurberg P (2011) Variation in thyroid function in subclinical hypothyroidism: importance of clinical follow-up and therapy. Eur J Endocrinol 164:317–323

    Article  PubMed  CAS  Google Scholar 

  • Kim YH, Fayos JV, Sisson JC (1980) Thyroid function following neck irradiation for malignant lymphoma. Radiology 134:205–208

    PubMed  CAS  Google Scholar 

  • Kumpulainen EJ, Hirvikoski PP, Virtaniemi JA et al (2000) Hypothyroidism after radiotherapy for laryngeal cancer. Radiother Oncol 57:97–101

    Article  PubMed  CAS  Google Scholar 

  • Kuten A, Lubochitski R, Fishman G et al (1996) Postradiotherapy hypothyroidism: radiation dose response and chemotherapeutic radiosensitization at less than 40 Gy. J Surg Oncol 61:281–283

    Article  PubMed  CAS  Google Scholar 

  • Leon X, Gras JR, Perez A et al (2002) Hypothyroidism in patients treated with total laryngectomy. A multivariate study. Eur Arch Otorhinolaryngol 259:193–196

    Article  PubMed  Google Scholar 

  • Liao Z, Ha CS, Vlachaki MT et al (2001) Mantle irradiation alone for pathologic stage I and II Hodgkin’s disease: long-term follow-up and patterns of failure. Int J Radiat Oncol Biol Phys 50:971–977

    Article  PubMed  CAS  Google Scholar 

  • Liening DA, Duncan NO, Blakeslee DB et al (1990) Hypothyroidism following radiotherapy for head and neck cancer. Otolaryngol Head Neck Surg 103:10–13

    PubMed  CAS  Google Scholar 

  • Markson JL, Flatman GE (1965) Myxoedema after Deep X-Ray Therapy to the Neck. Br Med J 1:1228–1230

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • McDougall IR, Coleman CN, Burke JS et al (1980) Thyroid carcinoma after high-dose external radiotherapy for Hodgkin’s disease: report of three cases. Cancer 45:2056–2060

    Article  PubMed  CAS  Google Scholar 

  • Mercado G, Adelstein DJ, Saxton JP et al (2001) Hypothyroidism: a frequent event after radiotherapy and after radiotherapy with chemotherapy for patients with head and neck carcinoma. Cancer 92:2892–2897

    Article  PubMed  CAS  Google Scholar 

  • Metayer C, Lynch CF, Clarke EA et al (2000) Second cancers among long-term survivors of Hodgkin’s disease diagnosed in childhood and adolescence. J Clin Oncol 18:2435–2443

    PubMed  CAS  Google Scholar 

  • Metzger ML, Hudson MM, Somes GW et al (2006a) White race as a risk factor for hypothyroidism after treatment for pediatric Hodgkin’s lymphoma. J Clin Oncol 24:1516–1521

    Article  PubMed  Google Scholar 

  • Metzger ML, Howard SC, Hudson MM et al (2006b) Natural history of thyroid nodules in survivors of pediatric Hodgkin lymphoma. Pediatr Blood Cancer 46:314–319

    Article  PubMed  Google Scholar 

  • Mihailescu DV, Schneider AB (2008) Size, number and distribution of thyroid nodules and their risk of malignancy in radiation-exposed patients who underwent surgery. J Clin Endocrinol Metab

    Google Scholar 

  • Neglia JP, Friedman DL, Yasui Y et al (2001) Second malignant neoplasms in five-year survivors of childhood cancer: childhood cancer survivor study. J Natl Cancer Inst 93:618–629

    Article  PubMed  CAS  Google Scholar 

  • Nelson DF, Reddy KV, O’Mara RE et al (1978) Thyroid abnormalities following neck irradiation for Hodgkin’s disease. Cancer 42:2553–2562

    Article  PubMed  CAS  Google Scholar 

  • Norris AA, Amdur RJ, Morris CG et al (2006) Hypothyroidism when the thyroid is included only in the low neck field during head and neck radiotherapy. Am J Clin Oncol 29:442–445

    Article  PubMed  Google Scholar 

  • Ozawa H, Saitou H, Mizutari K et al (2007) Hypothyroidism after radiotherapy for patients with head and neck cancer. Am J Otolaryngol 28:46–49

    Article  PubMed  Google Scholar 

  • Petersen M, Keeling CA, McDougall IR (1989) Hyperthyroidism with low radioiodine uptake after head and neck irradiation for Hodgkin’s disease. J Nucl Med 30:255–257

    PubMed  CAS  Google Scholar 

  • Posner MR, Ervin TJ, Miller D et al (1984) Incidence of hypothyroidism following multimodality treatment for advanced squamous cell cancer of the head and neck. Laryngoscope 94:451–454

    Article  PubMed  CAS  Google Scholar 

  • Rogoway WM, Finkelstein S, Rosenberg SA et al (1966) Myxedema developing after lymphangiography and neck radiation. Clin Res 14:133

    Google Scholar 

  • Ron E, Lubin JH, Shore RE et al (1995) Thyroid cancer after exposure to external radiation: a pooled analysis of seven studies. Radiat Res 141:259–277

    Article  PubMed  CAS  Google Scholar 

  • Ronckers CM, Sigurdson AJ, Stovall M et al (2006) Thyroid cancer in childhood cancer survivors: a detailed evaluation of radiation dose response and its modifiers. Radiat Res 166:618–628

    Article  PubMed  CAS  Google Scholar 

  • Rubin P, Cassarett G (1968) Clinical radiation pathology, WB Saunders Co

    Google Scholar 

  • Sankila R, Garwicz S, Olsen JH et al (1996) Risk of subsequent malignant neoplasms among 1,641 Hodgkin’s disease patients diagnosed in childhood and adolescence: a population-based cohort study in the five Nordic countries. Association of the nordic cancer registries and the nordic society of pediatric hematology and oncology. J Clin Oncol 14:1442–1446

    PubMed  CAS  Google Scholar 

  • Schneider AB, Recant W, Pinsky SM et al (1986) Radiation-induced thyroid carcinoma. Clinical course and results of therapy in 296 patients. Ann Intern Med 105:405–412

    Article  PubMed  CAS  Google Scholar 

  • Shafer RB, Nuttall FQ, Pollak K et al (1975) Thyroid function after radiation and surgery for head and neck cancer. Arch Intern Med 135:843–846

    Article  PubMed  CAS  Google Scholar 

  • Sigurdson AJ, Ronckers CM, Mertens AC et al (2005) Primary thyroid cancer after a first tumour in childhood (the childhood cancer survivor study): a nested case-control study. Lancet 365:2014–2023

    Article  PubMed  Google Scholar 

  • Sinard RJ, Tobin EJ, Mazzaferri EL et al (2000) Hypothyroidism after treatment for nonthyroid head and neck cancer. Arch Otolaryngol Head Neck Surg 126:652–657

    Article  PubMed  CAS  Google Scholar 

  • Sklar C, Whitton J, Mertens A et al (2000) Abnormalities of the thyroid in survivors of Hodgkin’s disease: data from the Childhood Cancer Survivor Study. J Clin Endocrinol Metab 85:3227–3232

    Article  PubMed  CAS  Google Scholar 

  • Smith RE Jr, Adler AR, Clark P et al (1981) Thyroid function after mantle irradiation in Hodgkin’s disease. JAMA 245:46–49

    Article  PubMed  Google Scholar 

  • Smith GL, Smith BD, Giordano SH et al (2008) Risk of hypothyroidism in older breast cancer patients treated with radiation. Cancer 112:1371–1379

    Article  PubMed  Google Scholar 

  • Smolarz K, Malke G, Voth E et al (2000) Hypothyroidism after therapy for larynx and pharynx carcinoma. Thyroid 10:425–429

    Article  PubMed  CAS  Google Scholar 

  • Svahn-Tapper G, Garwicz S, Anderson H et al (2006) Radiation dose and relapse are predictors for development of second malignant solid tumors after cancer in childhood and adolescence: a population-based case-control study in the five Nordic countries. Acta Oncol 45:438–448

    Article  PubMed  Google Scholar 

  • Tami TA, Gomez P, Parker GS et al (1992) Thyroid dysfunction after radiation therapy in head and neck cancer patients. Am J Otolaryngol 13:357–362

    Article  PubMed  CAS  Google Scholar 

  • Tamura K, Shimaoka K, Friedman M (1981) Thyroid abnormalities associated with treatment of malignant lymphoma. Cancer 47:2704–2711

    Article  PubMed  CAS  Google Scholar 

  • Taylor AJ, Croft AP, Palace AM et al (2009) Risk of thyroid cancer in survivors of childhood cancer: results from the British Childhood Cancer Survivor Study. Int J Cancer 125:2400–2405

    Article  PubMed  CAS  Google Scholar 

  • Tell R, Sjodin H, Lundell G et al (1997) Hypothyroidism after external radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys 39:303–308

    Article  PubMed  CAS  Google Scholar 

  • Tell R, Lundell G, Nilsson B et al (2004) Long-term incidence of hypothyroidism after radiotherapy in patients with head-and-neck cancer. Int J Radiat Oncol Biol Phys 60:395–400

    Article  PubMed  Google Scholar 

  • Thomas O, Mahe M, Campion L et al (2001) Long-term complications of total body irradiation in adults. Int J Radiat Oncol Biol Phys 49:125–131

    Article  PubMed  Google Scholar 

  • Tillman BN, Elbermani W (2007) (eds) Atlas of human anatomy, clinical edition, 1st edn. Mud Puddle Books Inc, New York, pp. 60

    Google Scholar 

  • Trotti A, Colevas AD, Setser A et al (2003) CTCAE v3.0: development of a comprehensive grading system for the adverse effects of cancer treatment. Semin Radiat Oncol 13:176–181

    Article  PubMed  Google Scholar 

  • Tucker MA, Jones PH, Boice JD Jr et al (1991) Therapeutic radiation at a young age is linked to secondary thyroid cancer. The late effects study group. Cancer Res 51:2885–2888

    PubMed  CAS  Google Scholar 

  • Turner SL, Tiver KW, Boyages SC (1995) Thyroid dysfunction following radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys 31:279–283

    Article  PubMed  CAS  Google Scholar 

  • Vrabec DP, Heffron TJ (1981) Hypothyroidism following treatment for head and neck cancer. Ann Otol Rhinol Laryngol 90:449–453

    PubMed  CAS  Google Scholar 

  • Warren S (1943) Effects of radiation on normal tissues. Pathol Lab Med 35:304–322

    Google Scholar 

  • Weissler MC, Berry BW (1991) Thyroid-stimulating hormone levels after radiotherapy and combined therapy for head and neck cancer. Head Neck 13:420–423

    Article  PubMed  CAS  Google Scholar 

  • Wolden SL, Lamborn KR, Cleary SF et al (1998) Second cancers following pediatric Hodgkin’s disease. J Clin Oncol 16:536–544

    PubMed  CAS  Google Scholar 

  • Wu YH, Wang HM, Chen HH et al (2010) Hypothyroidism after radiotherapy for nasopharyngeal cancer patients. Int J Radiat Oncol Biol Phys 76:1133–1139

    Article  PubMed  Google Scholar 

  • Yoden E, Soejima T, Maruta T et al (2004) Hypothyroidism after radiotherapy to the neck. Nippon Igaku Hoshasen Gakkai Zasshi 64:146–150

    PubMed  Google Scholar 

  • Zhang S (1999) An atlas of histology. Springer, New York

    Book  Google Scholar 

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Milano, M.T., Constine, L.S. (2014). Thyroid. In: Rubin, P., Constine, L., Marks, L. (eds) ALERT • Adverse Late Effects of Cancer Treatment. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-75863-1_8

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