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Archaeology of Human Pathogens: Palaeopathological Appraisal of Palaeoepidemiology

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Book cover Paleomicrobiology

The recent introduction of the new field of research of palaeomicrobiology has established new links between microbiological and archaeological sciences by using molecular techniques on archaeological material. However, although the material under study appears to be shared by both these fields, some of the methods, concepts, expectations and paradigms are not. The goal of this chapter is to present, from the bioanthropological and palaeopathological point of view, what ancient bones can tell us concerning the reconstruction of past infectious diseases from a palaeoepidemiological perspective.

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References

  • Aufderheide A, Rodriguez-Martin C (1998) The Cambridge encyclopedia of human paleopathology. Cambridge University Press

    Google Scholar 

  • Baker BJ (1999) Early manifestations of tuberculosis in the skeleton. In: Pàlfi Gy, Dutour O, Deak J, Hutas I (eds) Tuberculosis past and present. Golden Book, Budapest-Szeged, pp 301–310

    Google Scholar 

  • Baron H, Hummel S, Herrmann B (1996) Mycobacterium tuberculosis complex DNA in ancient human bones. J Archaeol Sci 23:667–671

    Article  Google Scholar 

  • Bello S (2000) Taphonomie des restes osseux humains. Effet des processus de conservation du squelette sur les paramètres anthropologiques. PhD Université de la Méditerranée, Faculté de Médecine de Marseille Universita’ degli studi di Firenze

    Google Scholar 

  • Bello S, Signoli M, Maczel M, Dutour O (1999) Evolution of mortality due to tuberculosis in France (18th–19th). In: Pàlfi Gy, Dutour O, Deak J, Hutas I (eds) Tuberculosis past and present. Golden Book, Budapest-Szeged, pp 93–104

    Google Scholar 

  • Bello S, Thomann A, Signoli M, Dutour O, Andrews P (2006) Age and sex bias in the reconstruction of past population structures. Am J Phys Anthropol 129:24–38

    Article  PubMed  Google Scholar 

  • Blaizot F, Alix G, Ferber E (2003) Le traitement funéraire des enfants décédés avant un an dans l’Antiquité: études de cas. Bull Mem Soc Anthropol Paris 15:1–2

    Google Scholar 

  • Boldsen JL (2001) Epidemiological approach to the paleopathological diagnosis of leprosy. Am J Phys Anthropol 115:380–387

    Article  PubMed  CAS  Google Scholar 

  • Brothwell D (1961) The palaeopathology of early man: an essay on the problems of diagnosis and analysis. J R Anthropol Inst 91:318–344

    Google Scholar 

  • Clarkson L (1975) Death, disease and famine in pre-industrial England. Gill/Macmillan, Dublin

    Google Scholar 

  • Cohen MN, Crane-Kramer G (2003) The state and future of paleoepidemiology. In: Greenblatt C, Spigelman M (eds) Emerging pathogens. Oxford University Press, Oxford, pp 79–91

    Google Scholar 

  • Combes C (2001) Parasitism ecology and evolution of intimate interactions. Chicago University Press, Chicago, IL

    Google Scholar 

  • Courtaud P, Romon T, Amouric H, Bruzek J, Dutour O, Tatilon C, Vallauri L, Verrand L (2005) Les cimetières d’esclaves. Exemple de l’ensemble d’Anse Sainte-Marguerite (le Moule, Guadeloupe). In: Ardagna Y, Boëtsch G, Dutour O, Lalys L, Signoli M (eds) L’homme et ses images. UMR 6578 Marseille, pp 325–338

    Google Scholar 

  • Cronje G (1984) Tuberculosis mortality decline in England and Wales, 1851–1910. In: Woods R, Woodward J (eds) Urban disease and mortality in 19th century England. Batsford, London, pp 79–101

    Google Scholar 

  • Crubézy LB, Poyeda JD, Clayton J, Crouau-Roy B, Montagnon D (1998) Identification of Mycobacterium DNA in an Egyptian Pott’s disease of 5, 400 years old. C R Acad Sci III 321:941–951

    PubMed  Google Scholar 

  • Darwin C (1859) The origin of species. Murray, London

    Google Scholar 

  • Davies PDO, Humphries MJ, Byfield SP, Nunn AJ, Darbyshire JH, Citron ICM, Fox W (1984) Bone and joint tuberculosis. J Bone Joint Surg 66B:320–330

    Google Scholar 

  • Delpech JM (1816) Précis élémentaire des maladies réputées chirurgicales. Méquignon-Marvis, Paris

    Google Scholar 

  • Donoghue HD, Spigelman M, Zias J, Gernaey-Child AM, Minnikin DE (1998) Mycobacterium tuberculosis complex DNA in calcified pleura from remains 1400 years old. Lett Appl Microbiol 27:265–269

    Article  PubMed  CAS  Google Scholar 

  • Drancourt M, Raoult D (2005) Palaeomicrobiology: current issues and perspectives. Nat Rev Microbiol 3:23–35

    Article  PubMed  CAS  Google Scholar 

  • Dutour O (1989) Hommes fossiles du Sahara. CNRS, Paris

    Google Scholar 

  • Dutour O, Signoli M, Georgeon E, da Silva J (1994) Le charnier de la Grande peste de Marseille (rue Leca): données de la fouille de la partie centrale et premiers résultats anthropologiques. Préhist Anthropol Médit 3:191–203

    Google Scholar 

  • Dutour O, Signoli M, Pàlfi G (1998) How to reconstruct the epidemiology of infectious diseases in the past? In: Greenblatt C (ed) Digging for pathogens. Balaban, Rehovot, pp 241–263

    Google Scholar 

  • Dutour O, Pàlfi Gy, Brun JP, Bérato J, Panuel M, Haas CJ, Zink A, Nerlich AG (1999) Morphological, paleoradiological and paleomicrobiological study of a French medieval case of Tuberculosis spondylitis with cold abscess. In: Pàlfi Gy, Dutour O, Deak J, Hutas I (eds) Tuberculosis past and present. Golden Book, Budapest-Szeged, pp 395–402

    Google Scholar 

  • Dutour O, Ardagna Y, Maczel M, Signoli M (2003) Epidemiology of infectious diseases in the past: Yersin, Koch and the skeletons. In: Greenblatt C, Spigelman M (eds) Emerging pathogens. Oxford University Press, Oxford, pp 151–165

    Google Scholar 

  • Fearman M, Jankauskas R, Gorski A, Bercovier H, Greenblatt CL (1999) Detecting Mycobaterium tuberculosis DNA in medieval skeletal remains from Lithuania: In: Pàlfi Gy, Dutour O, Deak J, Hutas I (eds) Tuberculosis past and present. Golden Book, Budapest-Szeged, pp 371–378

    Google Scholar 

  • Gerstman BB (2003) Epidemiology kept simple: an introduction to traditional and modern epidemiology, 2nd edn. Wiley-Liss, Hoboken, NJ

    Google Scholar 

  • Haas CJ, Zink A, Molnár E, Szeimies U, Reischl U, Marcsik A, Ardagna Y, Dutour O, Pálfi GY, Nerlich AG (2000) Molecular evidence for different stages of tuberculosis in ancient bone samples from Hungary. Am J Phys Anthropol 113:293–304

    Article  PubMed  CAS  Google Scholar 

  • Hershkovitz I, Greenwald CM, Latimer B, Jellema LM, Wish-Baratz S, Eshed V, Dutour O, Rothschild BM (2002) Serpens endocrania symmetrica (SES): a new term and a possible clue for identifying intrathoracic disease in skeletal populations. Am J Phys Anthropol 118:201–216

    Article  PubMed  Google Scholar 

  • Kelley MA, Micozzi MS (1984) Rib lesions in chronic pulmonary tuberculosis. Am J Phys Anthropol 65:381–386

    Article  PubMed  CAS  Google Scholar 

  • Lafond EM (1958) An analysis of adult skeletal tuberculosis. J Bone Joint Surg 40A:346–364

    Google Scholar 

  • Maczel M (2003) Sur les traces de la tuberculose: critères diagnostiques des atteintes infectieuses du squelette humain. PhD Université de la Méditerranée, Faculté de Médecine de Marseille Szeged University

    Google Scholar 

  • Maczel M, Dutour O, Ardagna Y, Panuel M, Zink A, Nerlich AG, Pàlfi G (2005) La série médiévale de l’Abbaye de la Celle, Var: données anthropologiques et paléopathologiques. In: Ardagna Y (ed) L’homme et ses images. UMR, Marseille 6578:393–402

    Google Scholar 

  • Masset C (1973) Influence du sexe et de l’âge sur la conservation des os humains. In: L’Homme, hier et aujourd’hui. Recueil d’études en Hommage à André Leroi-Gouhan. Cujas, Paris, pp 333–343

    Google Scholar 

  • Mays S (1992) Taphonomy factors in a human skeletal assemblage. Circaea 9:54–58

    Google Scholar 

  • Mays S, Taylor GM, Legge AJ, Young DB, Turner-Walker G (2001) Paleopathological and biomolecular study of tuberculosis in a medieval skeletal collection from England. Am J Phys Anthropol 114:298–311

    Article  PubMed  CAS  Google Scholar 

  • Medilexicon (2007) Medical Dictionary. http://www.medilexiconcom/©MediLexicon International

  • Menard V (1888) Tuberculose vertébrale. Asselin and Houzeau, Paris

    Google Scholar 

  • Nathanson E, Cohen W (1941) A statistical and roentgen analysis of two hundred cases of bone and joint tuberculosis. Radiology 36:550–567

    Google Scholar 

  • Nerlich AG, Haas CJ, Zink A, Szeimies U, Hagedorn HG (1997) Molecular evidence for tuberculosis in an ancient Egyptian mummy. Lancet 349:1760–1763

    Article  Google Scholar 

  • Nguyen TA (1988) Epidémiologie tropicale. ACCT

    Google Scholar 

  • Ortner DJ (1999) Paleopathology: implications for the history and evolution of tuberculosis. In: Pàlfi Gy, Dutour O, Deak J, Hutas I (eds) Tuberculosis past and present. Golden Book, Budapest-Szeged, pp 255–262

    Google Scholar 

  • Ortner DJ (2003) Identification of pathological conditions in human skeletal remains. Academic, Amsterdam

    Google Scholar 

  • Pàlfi G (1991) The first osteoarchaeological evidence of leprosy in Hungary. Int J Osteoarchaeol 1:99–102

    Article  Google Scholar 

  • Pàlfi G, Marcsik A (1999) Palaeoepidemiological data of tuberculosis in Hungary. In: Pàlfi Gy, Dutour O, Deak J, Hutas I (eds) Tuberculosis past and present. Golden Book, Budapest-Szeged, pp 533–542

    Google Scholar 

  • Pàlfi G, Ardagna Y, Molnar E, Dutour O, Panuel M, Haas CJ, Zink A, Nerlich AG (1999) Coexistence of tuberculosis and ankylosing spondylitis in a 7–8th century specimen. In: Pàlfi Gy, Dutour O, Deak J, Hutas I (eds) Tuberculosis past and present. Golden Book, Budapest-Szeged, pp 403–413

    Google Scholar 

  • Pap I, Jozsa L, Repa I, Bajzik G, Lakhani SR, Donoghue HD, Spigelman M (1999) 18–19th century tuberculosis in natural mummified individual (Vacs, Hungary). In: Pàlfi Gy, Dutour O, Deak J, Hutas I (eds) Tuberculosis past and present. Golden Book, Budapest-Szeged, pp 421–428

    Google Scholar 

  • Roberts C, Lucy D, Manchester K (1994) Inflammatory lesions of ribs: an analysis of the Terry Collection. Am J Phys Anthropol 95:169–182

    Article  PubMed  CAS  Google Scholar 

  • Salo WL, Aufderheide AC, Buikstra J, Holcomb TA (1994) Identification of Mycobacterium tuberculosis in a pre-Columbian Peruvian mummy. Proc Natl Acad Sci USA 91:2091–2094

    Article  PubMed  CAS  Google Scholar 

  • Santos AL, Roberts CA (2001) A picture of tuberculosis in young Portuguese people in the early 20th century: a multidisciplinary study of the skeletal and historical evidence. Am J Phys Anthropol 115:38–49

    Article  PubMed  CAS  Google Scholar 

  • Santos AL, Roberts CA (2006) Anatomy of a serial killer: differential diagnosis of tuberculosis based on rib lesions of adult individuals from the Coimbra Identified Skeletal Collection. Am J Phys Anthropol 130:38–49

    Article  PubMed  Google Scholar 

  • Schultz M (1999) The role of tuberculosis in infancy and childhood in prehistoric and historic population. In: Pàlfi Gy, Dutour O, Deak J, Hutas I (eds) Tuberculosis past and present. Golden Book, Budapest-Szeged, pp 503–510

    Google Scholar 

  • Sellier P (1996) La mise en évidence d’anomalies démographiques et leur interprétation: population, recrutement et pratiques funéraires du tumulus de Courtesoult. In: Piningre J-F (ed) Nécropoles et société au premier âge du Fer: le tumulus de Courtesoult (Haute-Saône). Documents d’Archéologie Française 54:188–202

    Google Scholar 

  • Sorrel E, Sorrel-Dejerine C (1932) Tuberculose osseuse et ostéo-articulaire. Masson, Paris

    Google Scholar 

  • Spigelman M, Lemma E (1993) The use of the polymerase chain reaction (PCR) to detect Mycobacterium tuberculosis in ancient skeletons. Int J Osteoarcheol 3:137–343

    Article  Google Scholar 

  • Steinbock RT (1976) Paleopathological diagnosis and interpretation. Thomas, Springfield, IL

    Google Scholar 

  • Stirland A, Waldron T (1990) The earliest cases of tuberculosis in Britain. J Archaeolog Sci 17:221–230

    Article  Google Scholar 

  • Taylor GM, Crossey M, Saldhana J, Waldron T (1996) DNA from Mycobacterium tuberculosis identified in mediaeval human skeletal remains using polymerase chain reaction. J Archaeol Sci 23:789–798

    Article  Google Scholar 

  • Taylor GM, Goyal M, Legge AJ, Shaw RJ, Young D (1999) Genotypic analysis of Mycobacterium tuberculosis from mediaeval human remains. Microbiology 145:899–904

    Article  PubMed  CAS  Google Scholar 

  • Ubelaker D (1998) Ancient disease in anthropological context. In: Greenblatt C (ed) Digging for pathogens. Balaban, Rehovot, pp 175–198

    Google Scholar 

  • Van Valen L (1973) A new evolutionary law. Evol Theory 1:1–30

    Google Scholar 

  • Wood JW, Milner GR, Harpending HC, Weiss KM (1992) The osteological paradox. Problems of inferring prehistoric health from skeletal samples. Curr Anthropol 33:343–370

    Article  Google Scholar 

  • Waldron T (1985) DISH at Merton Priory: evidence for a new occupational disease? BMJ 291:1762–1763

    Article  PubMed  CAS  Google Scholar 

  • Waldron T (1994) Counting the dead: the epidemiology of skeletal populations. Wiley, Chichester

    Google Scholar 

  • Waldron T (1999) The paleoepidemiology of tuberculosis: some problems considered. In: Pàlfi Gy, Dutour O, Deak J, Hutas I (eds) Tuberculosis past and present. Golden Book, Budapest-Szeged, pp 471–478

    Google Scholar 

  • Watts DJ (1989) Infant burials and Romano–British christianity. Archaeol J 146:372–383

    Google Scholar 

  • Zink A, Haas C, Reischl U, Szeimes U, Nerlich AG (2001) Molecular analysis of skeletal tuberculosis in an ancient Egyptian population. J Med Microbiol 50:355–366

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Anthropology, University of Toronto, 19 Russel Street, M5S 2S2, Toronto, ON, Canada

    Olivier Dutour

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  1. Olivier Dutour
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  1. Université de la Méditerranée, 27 Boulevard Jean Moulin, 13385, Marseille, France

    Didier Raoult  & Michel Drancourt  & 

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Dutour, O. (2008). Archaeology of Human Pathogens: Palaeopathological Appraisal of Palaeoepidemiology. In: Raoult, D., Drancourt, M. (eds) Paleomicrobiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-75855-6_8

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