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Humanized Mice pp 125–131Cite as

Human T Cell Development and HIV Infection in Human Hemato-Lymphoid System Mice

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 324))

Advances in generation of mice that on human hematopoietic stem and progenitor cell transplantation develop and maintain human hemato-lymphoid cells have fueled an already thriving field of research. We focus here on human T cell development and HIV infection in Rag2 -/-γc -/- mice transplanted as newborns with human CD34+ cord blood hematopoietic stem and progenitor cells.

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Author information

Authors and Affiliations

  1. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, 8091, Zurich, Switzerland

    S. Baenziger & R. F. Speck

  2. Institute for Research in Biomedicine, 6500, Bellinzona, Switzerland

    P. Ziegler & M. G. Manz

  3. Institute for Pathology, 6600, Locarno, Switzerland

    L. Mazzucchelli

  4. Department of Obstetrics and Gynecology, Ospedale San Giovanni, 6500, Bellinzona, Switzerland

    L. Bronz

Authors
  1. S. Baenziger
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  2. P. Ziegler
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  3. L. Mazzucchelli
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  4. L. Bronz
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  5. R. F. Speck
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  6. M. G. Manz
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Editor information

Editors and Affiliations

  1. Central Institute for Experimental Animals, 216-0001, Kawasaki, Japan

    Tatsuji Nomura M.D, Ph.D

  2. RIKEN, Yokohama, Japan

    Takeshi Watanabe M.D, Ph.D

  3. Tokai University School of Medicine, Kanagawa, Japan

    Sonoko Habu M.D, Ph.D

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© 2008 Springer-Verlag Berlin Heidelberg

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Baenziger, S., Ziegler, P., Mazzucchelli, L., Bronz, L., Speck, R.F., Manz, M.G. (2008). Human T Cell Development and HIV Infection in Human Hemato-Lymphoid System Mice. In: Nomura, T., Watanabe, T., Habu, S. (eds) Humanized Mice. Current Topics in Microbiology and Immunology, vol 324. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-75647-7_8

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