That which is understood of virulence phenotypes in the picornaviruses derives in large part from studies of artificially attenuating phenotypes rather than through examination of naturally occurring virus strains. The CVB replicate well in a variety of different murine and human cell cultures, making them excellent viruses with which to engage the problem of how the host environment interacts with specific viral genetics to promote varying efficiencies of viral replication. It is not known how highly virulent CVB strains may arise but evidence suggests such strains are not the norm.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2008 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Tracy, S., Gauntt, C. (2008). Group B Coxsackievirus Virulence. In: Tracy, S., Oberste, M.S., Drescher, K.M. (eds) Group B Coxsackieviruses. Current Topics in Microbiology and Immunology, vol 323. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-75546-3_3
Download citation
DOI: https://doi.org/10.1007/978-3-540-75546-3_3
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-75545-6
Online ISBN: 978-3-540-75546-3
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)