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Posttransplantation Lymphoproliferative Disorder

  • Chapter
Intraocular Inflammation

Abstract

Transplantation in children leads to various ocular impairment in 16 % of patients after 1 year, and posttransplantation lymphoproliferative disorder (PTLD) is a serious complication after solid organ transplantation. The lymphoproliferation is found rarely in the eye, and the ocular involvement was first described in 1991 by Brodsky et al. Epstein-Barr virus (EBV) seems to play a major role in induction of the proliferative process and subsequent development of lymphoma. The incidence of PTLD is approx 2–3 %. The highest incidence is seen in the first year after transplantation.

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Authors and Affiliations

  1. Centre of Ophthalmology, University of Tuebingen, Schleichstr. 12, Tuebingen, 72076, Germany

    Manfred Zierhut MD, PhD & Jens Martin Rohrbach

Authors
  1. Manfred Zierhut MD, PhD
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  2. Jens Martin Rohrbach
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Corresponding author

Correspondence to Manfred Zierhut MD, PhD .

Editor information

Editors and Affiliations

  1. Centre of Ophthalmology, University of Tuebingen, Tuebingen, Germany

    Manfred Zierhut

  2. Biomedical Research Centre, Institute of Ophthalmology, Moorfields Eyes Hospital, Department of Medical Retina, UCL, London, United Kingdom

    Carlos Pavesio

  3. School of Medicine, Department of Ophthalmology, Hokkaido University Graduate, Sapporo, Hokkaido, Japan

    Shigeaki Ohno

  4. University of Belo Horizonte, Belo Horizonte, Brazil

    Fernando Orefice

  5. USC Eye Institute, University of Southern California, Los Angeles, California, USA

    Narsing A. Rao

1 Electronic Supplementary Material

Below is the link to the electronic supplementary material.

Case Report 72

Unusual anterior uveitis in a child (PPT 9438 kb)

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Zierhut, M., Rohrbach, J.M. (2016). Posttransplantation Lymphoproliferative Disorder. In: Zierhut, M., Pavesio, C., Ohno, S., Orefice, F., Rao, N. (eds) Intraocular Inflammation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-75387-2_152

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  • DOI: https://doi.org/10.1007/978-3-540-75387-2_152

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-75385-8

  • Online ISBN: 978-3-540-75387-2

  • eBook Packages: MedicineMedicine (R0)

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