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Identifying Human MicroRNAs

  • Isaac Bentwich
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 320)

Abstract

MicroRNAs are a recently discovered group of short, non-coding RNA regulatory genes found in many species including humans. Originally viewed as a rare curiosity, over a thousand peer-reviewed publications have now established their major role in health and disease. MicroRNA discovery approaches, both biological and computational, have played an important role in this enfolding drama, and have led to the discovery of many hundreds of novel microRNAs. These different discovery and validation approaches are briefly reviewed here, as are the challenges and questions that lie ahead.

Keywords

Massively Parallel Signature Sequencing Entire Human Genome microRNA Precursor microRNA Sequence Human microRNAs 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Isaac Bentwich
    • 1
  1. 1.Rosetta Genomics Ltd.RehovotIsrael

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