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Reconstructing an Inversion History in the Anopheles Gambiae Complex

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Comparative Genomics (RECOMB-CG 2007)

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Abstract

The phylogenetic relationships among the members of species complexes can be inferred from the distribution of fixed inversions if outgroup arrangements are known. The Anopheles gambiae complex consists of seven African mosquito species that can be differentiated based on ten fixed inversions. However, the phylogenetic relationships among the members remain unclear. This paper demonstrates that physical maps of the outgroup speciesA. funestus and A. stephensi can be used for determining ancestral chromosome arrangements in the A. gambiae complex. Gene order comparisons have been performed using the Multiple Genome Rearrangements (MGR) and Sorting Permutation by Reversals and block-INterchanGes (SPRING) programs. The analysis has identified the chromosomal arrangements which are likely to be the ancestral in the complex.

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Glenn Tesler Dannie Durand

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© 2007 Springer-Verlag Berlin Heidelberg

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Xia, A., Sharakhova, M.V., Sharakhov, I.V. (2007). Reconstructing an Inversion History in the Anopheles Gambiae Complex. In: Tesler, G., Durand, D. (eds) Comparative Genomics. RECOMB-CG 2007. Lecture Notes in Computer Science(), vol 4751. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74960-8_11

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  • DOI: https://doi.org/10.1007/978-3-540-74960-8_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-74959-2

  • Online ISBN: 978-3-540-74960-8

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