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International Conference on Life System Modeling and Simulation

LSMS 2007: Life System Modeling and Simulation pp 354–363Cite as

Predicting Functional Protein-Protein Interactions Based on Computational Methods

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Part of the book series: Lecture Notes in Computer Science ((LNBI,volume 4689))

Abstract

Protein-protein interactions play a crucial role in the cellular process. In recent years, yet new experimental techniques have been developed to discover the protein-protein interaction networks, the accuracy and coverage has still proven to be limited. Computational approaches come into being essential both to assist in the design and validation of experimental studies and for the prediction of interacted proteins. This paper presents a survey of the major computational methods for detecting protein-protein interactions, and expatiates on their key contribution by introducing the experimental methods, the typical computational methods and the improvement over them in turn.

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Authors and Affiliations

  1. School of Computer Science and Technology, Shanghai University, Shanghai, 200072, China

    Luwen Zhang & Wu Zhang

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  1. Luwen Zhang
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  2. Wu Zhang
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Editor information

Kang Li Xin Li George William Irwin Gusen He

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© 2007 Springer-Verlag Berlin Heidelberg

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Zhang, L., Zhang, W. (2007). Predicting Functional Protein-Protein Interactions Based on Computational Methods. In: Li, K., Li, X., Irwin, G.W., He, G. (eds) Life System Modeling and Simulation. LSMS 2007. Lecture Notes in Computer Science(), vol 4689. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74771-0_40

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  • DOI: https://doi.org/10.1007/978-3-540-74771-0_40

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-74770-3

  • Online ISBN: 978-3-540-74771-0

  • eBook Packages: Computer ScienceComputer Science (R0)

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